DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ lunde-2010-1 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. DIP original experiment: DIP-218347X Nature structural & molecular biology 2010 IMEx Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. Only protein-protein interactions imex curation lunde-2010-2 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. DIP original experiment: DIP-218345X Nature structural & molecular biology 2010 IMEx Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. Only protein-protein interactions imex curation lunde-2010-3 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. DIP original experiment: DIP-218346X Nature structural & molecular biology 2010 IMEx Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. Only protein-protein interactions imex curation lunde-2010-4 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. DIP original experiment: DIP-218348X Nature structural & molecular biology 2010 IMEx Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Lunde BM., Reichow SL., Kim M., Suh H., Leeper TC., Yang F., Mutschler H., Buratowski S., Meinhart A., Varani G. Only protein-protein interactions imex curation pcf11_yeast Protein PCF11 PCF11 YDR228C YD9934.13C protein 1 of CF I protein protein yeast Saccharomyces cerevisiae Baker's yeast MDHDTEVIVKDFNSILEELTFNSRPIITTLTKLAEENISCAQYFVDAIESRIEKCMPKQKLYAFYALDSICKNVGSPYTIYFSRNLFNLYKRTYLLVDNTTRTKLINMFKLWLNPNDTGLPLFEGSALEKIEQFLIKASALHQKNLQAMLPTPTVPLLLRDIDKLTCLTSERLKNQPNDEKLKMKLLVLSQLKQELKREKLTLNALKQVQMQLRQVFSQDQQVLQERMRYHELQQQQQQQQQQQQQQQQQQQQYHETKDMVGSYTQNSNSAIPLFGNNSDTTNQQNSLSSSLFGNISGVESFQEIEKKKSLNKINNLYASLKAEGLIYTPPKESIVTLYKKLNGHSNYSLDSHEKQLMKNLPKIPLLNDILSDCKAYFATVNIDVLNNPSLQLSEQTLLQENPIVQNNLIHLLYRSKPNKCSVCGKRFGNSESEKLLQNEHLDWHFRINTRIKGSQNTANTGISNSNLNTTTTRKNIQSRNWYLSDSQWAAFKDDEITSTKHKNDYTDPHANKNIDKSALNIHADENDEGSVDNTLGSDRSNELEIRGKYVVVPETSQDMAFKCPICKETVTGVYDEESGEWVWKNTIEVNGKYFHSTCYHETSQNSSKSNSGKVGLDDLKKLVTK 66F91BA9577E82F1 ctd-1 C-terminal domain peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) YSPTSPSYSPTSPS rt103_yeast Regulator of Ty1 transposition protein 103 RTT103 YDR289C protein protein yeast Saccharomyces cerevisiae Baker's yeast MPFSSEQFTTKLNTLEDSQESISSASKWLLLQYRDAPKVAEMWKEYMLRPSVNTRRKLLGLYLMNHVVQQAKGQKIIQFQDSFGKVAAEVLGRINQEFPRDLKKKLSRVVNILKERNIFSKQVVNDIERSLKTESSPVEALVLPQKLKDFAKDYEKLVKMHHNVCAMKMRFDKSSDELDPSSSVYEENFKTISKIGNMAKDIINESILKRESGIHKLQSTLDDEKRHLDEEQNMLSEIEFVLSAKDPSRLNKNVDEDNIIPTYEVGDGDDDDDDGDNDDDDDDDDDDKNYDDRSNDSNYGVTNISTTDKKNEVVEKTDSEHKNSTHNPSDNQFGMKRTHDMIGHDDANDIPEKKVHLDSKTSEDGTFNSEDGHYELDIEGHVGAQTDEGVENSGGVSSSIQDLLSKLAN 08D37739466E3010 ctd-pcf11-1 3213967 N/A 3213971 unspecified role unspecified role unspecified role unspecified role CTD-interacting domain Region 1-140 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3213972 unspecified role unspecified role unspecified role unspecified role in vitro In vitro direct interaction direct interaction false false false ctd-rtt103-2 3213968 N/A 3213972 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3213973 unspecified role unspecified role unspecified role unspecified role CTD-interacting domain Region 1-131 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ctd-rtt103-3 3213969 N/A 3213972 unspecified role unspecified role unspecified role unspecified role Fluorescein-label Fluorescein-label fluorescein fluorescein label fluorescein n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false in vitro In vitro N/A 3213973 unspecified role unspecified role unspecified role unspecified role CTD-interacting domain Region 1-131 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q05543:p.Arg108Asn R108N mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ctd-pcf11-2 3213970 N/A 3213971 unspecified role unspecified role unspecified role unspecified role CTD-interacting domain Region 1-140 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3213972 unspecified role unspecified role unspecified role unspecified role Fluorescein-label Fluorescein-label fluorescein fluorescein label fluorescein n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false in vitro In vitro direct interaction direct interaction false false false