DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ holloway-2010-1 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254611X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-2 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254603X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-3 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254606X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-4 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254604X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-5 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254609X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-6 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254607X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254605X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-8 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254608X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation holloway-2010-9 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. DIP original experiment: DIP-254610X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Holloway KR., Calhoun TN., Saxena M., Metoyer CF., Kandler EF., Rivera CA., Pruitt K. Only protein-protein interactions imex curation dvl3_human Segment polarity protein dishevelled homolog DVL-3 DVL3 KIAA0208 DSH homolog 3 protein protein human Homo sapiens Human MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM sir1_human NAD-dependent protein deacetylase sirtuin-1 NAD-dependent protein deacylase sirtuin-1 SIRT1 SIR2L1 SIR2-like protein 1 Regulatory protein SIR2 homolog 1 protein protein human Homo sapiens Human MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS dvl1_human Segment polarity protein dishevelled homolog DVL-1 DVL1 DSH homolog 1 protein protein human Homo sapiens Human MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM q86th3_human DVL1 protein protein human Homo sapiens Human MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLTRKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM csk21_human Casein kinase II subunit alpha CSNK2A1 CK2A1 protein protein human Homo sapiens Human MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ ctnb1_human Catenin beta-1 Beta-catenin OK/SW-cl.35 PRO2286 CTNNB1 CTNNB protein protein human Homo sapiens Human MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL dvl2_human Segment polarity protein dishevelled homolog DVL-2 DSH homolog 2 DVL2 protein protein human Homo sapiens Human MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM sirt1-dvl3-1 3208287 N/A 3208296 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human physical association physical association false false false sirt1-dvl1-1 3208288 N/A 3208298 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false dvl3-sirt1-1 3208289 N/A 3208296 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3208297 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false sirt1-dvl1-2 3208290 N/A 3208298 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false sirt1-dvl1-3 3208291 N/A 3208299 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human physical association physical association false false false sirt1-csnk2a1-2 3208292 N/A 3208300 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false sirt1-dvl3-2 3208293 N/A 3208296 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false ctnnb1-sirt1-1 3208294 N/A 3208301 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3208297 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false sirt1-dvl2-1 3208295 N/A 3208302 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3208297 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human physical association physical association false false false