DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ seiradake-2010-1 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Seiradake E., Harlos K., Sutton G., Aricescu AR., Jones EY. DIP original experiment: DIP-217043X Nature structural & molecular biology 2010 IMEx An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Seiradake E., Harlos K., Sutton G., Aricescu AR., Jones EY. Only protein-protein interactions imex curation seiradake-2010-2 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Seiradake E., Harlos K., Sutton G., Aricescu AR., Jones EY. DIP original experiment: DIP-217041X Nature structural & molecular biology 2010 IMEx An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Seiradake E., Harlos K., Sutton G., Aricescu AR., Jones EY. Only protein-protein interactions imex curation seiradake-2010-3 in vitro In vitro light scattering light scattering predetermined predetermined participant predetermined Seiradake E., Harlos K., Sutton G., Aricescu AR., Jones EY. DIP original experiment: DIP-217042X Nature structural & molecular biology 2010 IMEx An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Seiradake E., Harlos K., Sutton G., Aricescu AR., Jones EY. Only protein-protein interactions imex curation efna5_human Ephrin-A5 EFNA5 EPLG7 LERK7 EPH-related receptor tyrosine kinase ligand 7 AL-1 protein protein human Homo sapiens Human MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL epha2_human Ephrin type-A receptor 2 Tyrosine-protein kinase receptor ECK Epithelial cell kinase EPHA2 ECK protein protein human Homo sapiens Human MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI efna5-epha2-1 3206035 N/A 3206038 unspecified role unspecified role unspecified role unspecified role RBD domain Region 27-166 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3206039 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 27-534 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false efna5-epha2-2 3206036 N/A 3206038 unspecified role unspecified role unspecified role unspecified role RBD domain Region 27-166 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3206039 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 27-534 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false efna5-epha2-3 3206037 N/A 3206038 unspecified role unspecified role unspecified role unspecified role RBD domain Region 27-166 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3206039 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 27-534 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false