DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ ciatto-2010-1 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217037X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions imex curation ciatto-2010-2 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217034X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions imex curation ciatto-2010-3 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217035X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions imex curation ciatto-2010-4 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217036X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions imex curation ciatto-2010-5 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217038X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions imex curation q8vdk4_mouse Cadherin-13 Cdh13 protein protein mouse Mus musculus Mouse MQPRTPLTLCVLLSQVLLVTSADDLECTPGFQQKVLHIHQPAEFIEDQPVLNLTFSDCKGNEKLHYEVSSPHFKVNSDGTLVALRNITAVGRTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPEGSKFRLTGKGVDQDPKGTFRINENTGSVSVTRTLDRETIATYQLYVETTDASGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIVIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTKQENISVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLSINPINGTVDTTAVLDRESPFVHNSVYTALFLAIDSGNPPATGTGTLLITLEDINDNAPVIYPTVAEVCDDARNLSVVILGASDKDLHPNTDPFKFEIHKQTVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCKNSKVDCNGAGALHLSLSLLLLFSLLSLLSGL mint cad13_chick Cadherin-13 CDH13 Truncated cadherin protein protein chick Gallus gallus (Chicken) Chicken MQHKTQLTLSFLLSQVLLLACAEDLECTPGFQQKVFYIEQPFEFTEDQPILNLVFDDCKGNNKLNFEVSNPDFKVEHDGSLVALKNVSEAGRALFVHARSEHAEDMAEILIVGADEKHDALKEIFKIEGNLGIPRQKRAILATPILIPENQRPPFPRSVGKVIRSEGTEGAKFRLSGKGVDQDPKGIFRINEISGDVSVTRPLDREAIANYELEVEVTDLSGKIIDGPVRLDISVIDQNDNRPMFKEGPYVGHVMEGSPTGTTVMRMTAFDADDPSTDNALLRYNILKQTPTKPSPNMFYIDPEKGDIVTVVSPVLLDRETMETPKYELVIEAKDMGGHDVGLTGTATATILIDDKNDHPPEFTKKEFQATVKEGVTGVIVNLTVGDRDDPATGAWRAVYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLIPDIAYGPSSTATVQITVEDVNEGPVFHPNPMTVTKQENIPIGSIVLTVNATDPDTLQHQTIRYSVYKDPASWLEINPTNGTVATTAVLDRESPHVQDNKYTALFLAIDSGNPPATGTGTLHITLEDVNDNVPSLYPTLAKVCDDAKDLRVVVLGASDKDLHPNTDPFKFELSKQSGPEKLWRINKLNNTHAQVVLLQNLKKANYNIPISVTDSGKPPLTNNTELKLQVCSCKKSRMDCSASDALHISMTLILLSLFSLFCL cadh1_mouse Cadherin-1 Epithelial cadherin Uvomorulin ARC-1 Cdh1 protein protein mouse Mus musculus Mouse MGARCRSFSALLLLLQVSSWLCQELEPESCSPGFSSEVYTFPVPERHLERGHVLGRVRFEGCTGRPRTAFFSEDSRFKVATDGTITVKRHLKLHKLETSFLVRARDSSHRELSTKVTLKSMGHHHHRHHHRDPASESNPELLMFPSVYPGLRRQKRDWVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPVFNPSTYQGQVPENEVNARIATLKVTDDDAPNTPAWKAVYTVVNDPDQQFVVVTDPTTNDGILKTAKGLDFEAKQQYILHVRVENEEPFEGSLVPSTATVTVDVVDVNEAPIFMPAERRVEVPEDFGVGQEITSYTAREPDTFMDQKITYRIWRDTANWLEINPETGAIFTRAEMDREDAEHVKNSTYVALIIATDDGSPIATGTGTLLLVLLDVNDNAPIPEPRNMQFCQRNPQPHIITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAAQESLILQPRKDLEIGEYKIHLKLADNQNKDQVTTLDVHVCDCEGTVNNCMKAGIVAAGLQVPAILGILGGILALLILILLLLLFLRRRTVVKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD cdh13-cdh13-1 3205260 N/A 3205265 unspecified role unspecified role bait bait EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3205265 unspecified role unspecified role prey prey EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q8VDK4:p.Arg152Glu R152E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false Q8VDK4:p.[Arg152Glu;Asp278Ser] R152E/D278S mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Q8VDK4:p.Arg152Ser R152S mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false Q8VDK4:p.[Arg152Ser;Asp278Ser] R152S/D278S mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh13-1 3205261 N/A 3205266 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh13-2 3205262 N/A 3205265 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q8VDK4:p.Arg152Glu R152E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh13-3 3205263 N/A 3205265 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh1-10 3205264 N/A 3205267 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false