DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ harrison-2010-2 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217026X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-3 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217023X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-4 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217030X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-5 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217028X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-6 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217031X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-7 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217024X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-8 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217029X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-9 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217027X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-10 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217025X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-11 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217032X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation harrison-2010-12 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. DIP original experiment: DIP-217033X Nature structural & molecular biology 2010 IMEx Two-step adhesive binding by classical cadherins. Harrison OJ., Bahna F., Katsamba PS., Jin X., Brasch J., Vendome J., Ahlsen G., Carroll KJ., Price SR., Honig B., Shapiro L. Only protein-protein interactions imex curation cadh1_mouse Cadherin-1 Epithelial cadherin Uvomorulin ARC-1 Cdh1 protein protein mouse Mus musculus Mouse MGARCRSFSALLLLLQVSSWLCQELEPESCSPGFSSEVYTFPVPERHLERGHVLGRVRFEGCTGRPRTAFFSEDSRFKVATDGTITVKRHLKLHKLETSFLVRARDSSHRELSTKVTLKSMGHHHHRHHHRDPASESNPELLMFPSVYPGLRRQKRDWVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPVFNPSTYQGQVPENEVNARIATLKVTDDDAPNTPAWKAVYTVVNDPDQQFVVVTDPTTNDGILKTAKGLDFEAKQQYILHVRVENEEPFEGSLVPSTATVTVDVVDVNEAPIFMPAERRVEVPEDFGVGQEITSYTAREPDTFMDQKITYRIWRDTANWLEINPETGAIFTRAEMDREDAEHVKNSTYVALIIATDDGSPIATGTGTLLLVLLDVNDNAPIPEPRNMQFCQRNPQPHIITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAAQESLILQPRKDLEIGEYKIHLKLADNQNKDQVTTLDVHVCDCEGTVNNCMKAGIVAAGLQVPAILGILGGILALLILILLLLLFLRRRTVVKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD q3knz1_mouse Cdh6 protein protein mouse Mus musculus Mouse MRTYRYFLLLFWVGQPYPTFSNPLSKRTSGFPAKRKALELSANSRNELSRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAVNRRTGRPVEPESEFIIKIHDINDNEPIFTKDVYTATVPEMADVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGHEMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPHVEPRFLYLGPFKDSATVRIVVDDVDEPPVFSKLAYILQIREDARINTTIGSVAAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLRAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAMEDSKSRRDIVPEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDGDQDYDYLSDWGPRFKKLADMYGGMDSDKDS cadh2_mouse Cadherin-2 Cdh2 Neural cadherin protein protein mouse Mus musculus Mouse MCRIAGAPRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLPKDVHEGQPLLNVKFSNCNRKRKVQYESSEPADFKVDEDGTVYAVRSFPLTAEQAKFLIYAQDKETQEKWQVAVNLSREPTLTEEPMKEPHEIEEIVFPRQLAKHSGALQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPEPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTINRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRLDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGDQDYDYLNDWGPRFKKLADMYGGGDD cdh1-cdh1-1 3205196 N/A 3205207 unspecified role unspecified role prey prey EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3205207 unspecified role unspecified role bait bait EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false P09803:p.Lys170Glu K170E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false P09803:p.Tyr298Arg Y298R mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh1-7 3205197 N/A 3205207 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh6-1 3205198 N/A 3205208 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q3KNZ1:p.[Trp57Ala;Met241Asp] M241D/W57A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh6-2 3205199 N/A 3205208 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh6-cdh6-1 3205200 N/A 3205208 unspecified role unspecified role prey prey EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3205208 unspecified role unspecified role bait bait EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q3KNZ1:p.Met241Asp M241D mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh1-8 3205201 N/A 3205207 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false P09803:p.[Trp158Ala;Lys170Glu] K170E/W158A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh6-3 3205202 N/A 3205208 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh1-cdh1-2 3205203 N/A 3205207 unspecified role unspecified role prey prey EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false P09803:p.Lys170Glu K170E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false P09803:p.Tyr298Arg Y298R mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false P09803:p.Lys170Ser K170S mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3205207 unspecified role unspecified role bait bait EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh1-9 3205204 N/A 3205207 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh6-cdh6-2 3205205 N/A 3205208 unspecified role unspecified role prey prey EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q3KNZ1:p.Met241Asp M241D mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3205208 unspecified role unspecified role bait bait EC1-EC2 domain Region 54-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cdh2-4 3205206 N/A 3205209 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 160-374 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false