DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ carafoli-2009-1 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Carafoli F., Bihan D., Stathopoulos S., Konitsiotis AD., Kvansakul M., Farndale RW., Leitinger B., Hohenester E. DIP original experiment: DIP-132337X Structure (London, England : 1993) 2009 IMEx Crystallographic insight into collagen recognition by discoidin domain receptor 2. Carafoli F., Bihan D., Stathopoulos S., Konitsiotis AD., Kvansakul M., Farndale RW., Leitinger B., Hohenester E. Only protein-protein interactions imex curation carafoli-2009-2 in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Carafoli F., Bihan D., Stathopoulos S., Konitsiotis AD., Kvansakul M., Farndale RW., Leitinger B., Hohenester E. DIP original experiment: DIP-132339X Structure (London, England : 1993) 2009 IMEx Crystallographic insight into collagen recognition by discoidin domain receptor 2. Carafoli F., Bihan D., Stathopoulos S., Konitsiotis AD., Kvansakul M., Farndale RW., Leitinger B., Hohenester E. Only protein-protein interactions imex curation carafoli-2009-3 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Carafoli F., Bihan D., Stathopoulos S., Konitsiotis AD., Kvansakul M., Farndale RW., Leitinger B., Hohenester E. DIP original experiment: DIP-132338X Structure (London, England : 1993) 2009 IMEx Crystallographic insight into collagen recognition by discoidin domain receptor 2. Carafoli F., Bihan D., Stathopoulos S., Konitsiotis AD., Kvansakul M., Farndale RW., Leitinger B., Hohenester E. Only protein-protein interactions imex curation collagenpeptide3 Collagen peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) GPPGPPGPPGPRGQPGVMGFPGPPGPPG ddr2_human Discoidin domain-containing receptor 2 Discoidin domain-containing receptor tyrosine kinase 2 DDR2 NTRKR3 TKT TYRO10 Receptor protein-tyrosine kinase TKT Tyrosine-protein kinase TYRO10 Neurotrophic tyrosine kinase, receptor-related 3 CD167 antigen-like family member B protein protein human Homo sapiens Human MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE collagenpeptide5 Collagen peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) GPCGPPGPPGPPGPPGPPGPRGQPGVMGFPGPPGPPGPPGPPGPPGPC collagenpeptide3-ddr2-1 3200793 N/A 3200796 unspecified role unspecified role unspecified role unspecified role Hydroxyproline Hydroxyproline 4hypro 4-hydroxy-L-proline (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid 4-hydroxy-L-proline 4-hydroxylated L-proline 4-hydroxyproline 4-trans-hydroxy-L-proline L-threo-4-hydroxyproline MOD_RES 4-hydroxyproline gamma-hydroxypyrrolidine-alpha-carboxylic acid 4HyPro certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Norleucine Norleucine modres protein modification ModRes certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3200797 unspecified role unspecified role unspecified role unspecified role Discoidin Domain Region 26-190 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false collagenpeptide5-ddr2-1 3200794 N/A 3200798 unspecified role unspecified role bait bait Hydroxyproline Hydroxyproline 4hypro 4-hydroxy-L-proline (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid 4-hydroxy-L-proline 4-hydroxylated L-proline 4-hydroxyproline 4-trans-hydroxy-L-proline L-threo-4-hydroxyproline MOD_RES 4-hydroxyproline gamma-hydroxypyrrolidine-alpha-carboxylic acid 4HyPro certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3200797 unspecified role unspecified role prey prey Extracellular domain Region 22-398 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false collagenpeptide3-ddr2-2 3200795 N/A 3200796 unspecified role unspecified role unspecified role unspecified role Hydroxyproline Hydroxyproline 4hypro 4-hydroxy-L-proline (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid 4-hydroxy-L-proline 4-hydroxylated L-proline 4-hydroxyproline 4-trans-hydroxy-L-proline L-threo-4-hydroxyproline MOD_RES 4-hydroxyproline gamma-hydroxypyrrolidine-alpha-carboxylic acid 4HyPro certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Norleucine Norleucine modres protein modification ModRes certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3200797 unspecified role unspecified role unspecified role unspecified role Discoidin Domain Region 26-190 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false