DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dang-2009-1 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Dang L., White DW., Gross S., Bennett BD., Bittinger MA., Driggers EM., Fantin VR., Jang HG., Jin S., Keenan MC., Marks KM., Prins RM., Ward PS., Yen KE., Liau LM., Rabinowitz JD., Cantley LC., Thompson CB., Vander Heiden MG., Su SM. DIP original experiment: DIP-219672X Nature 2009 IMEx Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Dang L., White DW., Gross S., Bennett BD., Bittinger MA., Driggers EM., Fantin VR., Jang HG., Jin S., Keenan MC., Marks KM., Prins RM., Ward PS., Yen KE., Liau LM., Rabinowitz JD., Cantley LC., Thompson CB., Vander Heiden MG., Su SM. Only protein-protein interactions imex curation dang-2009-2 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Dang L., White DW., Gross S., Bennett BD., Bittinger MA., Driggers EM., Fantin VR., Jang HG., Jin S., Keenan MC., Marks KM., Prins RM., Ward PS., Yen KE., Liau LM., Rabinowitz JD., Cantley LC., Thompson CB., Vander Heiden MG., Su SM. DIP original experiment: DIP-219673X Nature 2009 IMEx Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Dang L., White DW., Gross S., Bennett BD., Bittinger MA., Driggers EM., Fantin VR., Jang HG., Jin S., Keenan MC., Marks KM., Prins RM., Ward PS., Yen KE., Liau LM., Rabinowitz JD., Cantley LC., Thompson CB., Vander Heiden MG., Su SM. Only protein-protein interactions imex curation idhc_human Isocitrate dehydrogenase [NADP] cytoplasmic Cytosolic NADP-isocitrate dehydrogenase Oxalosuccinate decarboxylase NADP(+)-specific ICDH IDP IDH1 PICD protein protein human Homo sapiens Human MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL idh1-1 3199299 N/A 3199301 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false idh1-2 3199300 N/A 3199301 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false