DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ lovejoy-2009-1 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134753X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-2 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134744X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-3 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134751X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-4 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134747X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-5 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134749X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-6 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134745X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134750X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-8 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134752X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-9 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134748X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation lovejoy-2009-10 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. DIP original experiment: DIP-134746X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Functional genomic screens identify CINP as a genome maintenance protein. Lovejoy CA., Xu X., Bansbach CE., Glick GG., Zhao R., Ye F., Sirbu BM., Titus LC., Shyr Y., Cortez D. Only protein-protein interactions imex curation atrip_human ATR-interacting protein ATM and Rad3-related-interacting protein ATRIP AGS1 protein protein human Homo sapiens Human MAGTSAPGSKRRSEPPAPRPGPPPGTGHPPSKRARGFSAAAAPDPDDPFGAHGDFTADDLEELDTLASQALSQCPAAARDVSSDHKVHRLLDGMSKNPSGKNRETVPIKDNFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVVRALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG cinp_human Cyclin-dependent kinase 2-interacting protein CINP protein protein human Homo sapiens Human MEAKTLGTVTPRKPVLSVSARKIKDNAADWHNLILKWETLNDAGFTTANNIANLKISLLNKDKIELDSSSPASKENEEKVCLEYNEELEKLCEELQATLDGLTKIQVKMEKLSSTTKGICELENYHYGEESKRPPLFHTWPTTHFYEVSHKLLEMYRKELLLKRTVAKELAHTGDPDLTLSYLSMWLHQPYVESDSRLHLESMLLETGHRAL atr_human Serine/threonine-protein kinase ATR ATR FRP1 Ataxia telangiectasia and Rad3-related protein FRAP-related protein 1 protein protein human Homo sapiens Human MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSHEAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLSQLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAGYESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYSGLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFYTKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHGMFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKSASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYATDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGHQLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITKVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQHTINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTKAYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM cinp-atrip-2 3198415 N/A 3198425 unspecified role unspecified role prey prey Region 118-156 Region 118-156 sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3198426 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction false false false atrip-cinp-1 3198416 N/A 3198426 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3198425 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction false false false atr-atrip-2 3198417 N/A 3198425 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3198427 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3198426 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false cinp-atrip-3 3198418 N/A 3198425 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3198426 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false cinp-atr-1 3198419 N/A 3198427 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3198426 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false atrip-cinp-2 3198420 N/A 3198426 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3198425 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false cinp-atr-2 3198421 N/A 3198425 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3198427 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3198426 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false cinp-atrip-4 3198422 N/A 3198426 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3198425 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 118-156 Region 118-156 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human physical association physical association false false false cinp-atr-3 3198423 N/A 3198427 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3198426 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false atr-cinp-1 3198424 N/A 3198427 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3198426 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false