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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3196906">
                <names>
                    <shortLabel>alterio-2009-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="19805286" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3IAI" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14823" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15806663" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-134542X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0908301106" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="7108">
                        <names>
                            <shortLabel>spofr</shortLabel>
                            <fullName>Spodoptera frugiperda (Fall armyworm)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Fall armyworm</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Alterio V., Hilvo M., Di Fiore A., Supuran CT., Pan P., Parkkila S., Scaloni A., Pastorek J., Pastorekova S., Pedone C., Scozzafava A., Monti SM., De Simone G.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-134542X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2009</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Alterio V.,  Hilvo M.,  Di Fiore A.,  Supuran CT.,  Pan P.,  Parkkila S.,  Scaloni A.,  Pastorek J.,  Pastorekova S.,  Pedone C.,  Scozzafava A.,  Monti SM.,  De Simone G.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3196907">
                <names>
                    <shortLabel>cah9_human</shortLabel>
                    <fullName>Carbonic anhydrase 9</fullName>
                    <alias typeAc="MI:0301" type="gene name">CA9</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Carbonate dehydratase IX</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Carbonic anhydrase IX</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">G250</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MN</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Membrane antigen MN</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">P54/58N</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Renal cell carcinoma-associated antigen G250</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">pMW1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q16790" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3IAI" version="SP_197"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-12259996" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000107159" version="SP_197" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016836" secondary="hydro-lyase activity" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TL5" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2HKF" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FL5" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FL4" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RQN" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QUT" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y74" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023561" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TL6" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004089" secondary="carbonate dehydratase activity" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QN2" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031528" secondary="microvillus membrane" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RQW" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006730" secondary="one-carbon metabolic process" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RQQ" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G98" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002009" secondary="morphogenesis of an epithelium" version="SP_197"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48973N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000378357" version="SP_197" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FE2" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QN5" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_197"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001207.2"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FE1" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QN6" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018429" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FE0" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1475029" version="SP_197"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000367608" version="SP_197" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033574" secondary="response to testosterone" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001148" version="SP_197"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1234158" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_197"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046903" secondary="secretion" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6RQU" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018338" version="SP_197"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036398" version="SP_197"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5T4R1" version="SP_159" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DVX" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6G9U" version="SP_197"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FL6" version="SP_197"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLVPVHPQRLPRMQEDSPLGGGSSGEDDPLGEEDLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-14823-1" id="3196908">
                <names>
                    <shortLabel>ca9-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-104063E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14823-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15806675" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3196906</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3196909">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15806679" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3196907</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3196910">
                                <names>
                                    <shortLabel>Region 137-391</shortLabel>
                                    <fullName>Region 137-391</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15806680" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="137"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="391"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="7108">
                                <names>
                                    <shortLabel>spofr</shortLabel>
                                    <fullName>Spodoptera frugiperda (Fall armyworm)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Fall armyworm</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
