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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
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            <attributeList>
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                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
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                <names>
                    <shortLabel>matrone-2009-1</shortLabel>
                </names>
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                        <primaryRef db="pubmed" dbAc="MI:0446" id="19549834" refType="primary-reference" refTypeAc="MI:0358"/>
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                            <shortLabel>rat</shortLabel>
                            <fullName>Rattus norvegicus (Rat)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
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                <interactionDetectionMethod>
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                <participantIdentificationMethod>
                    <names>
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                        <fullName>western blot</fullName>
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                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                    <attribute name="author-list" nameAc="MI:0636">Matrone C., Marolda R., Ciafrè S., Ciotti MT., Mercanti D., Calissano P.</attribute>
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                    <attribute name="publication year" nameAc="MI:0886">2009</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation.</attribute>
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                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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            </experimentDescription>
            <experimentDescription id="3193216">
                <names>
                    <shortLabel>matrone-2009-2</shortLabel>
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                        <names>
                            <shortLabel>rat</shortLabel>
                            <fullName>Rattus norvegicus (Rat)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
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                    <names>
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                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
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                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                    <attribute name="author-list" nameAc="MI:0636">Matrone C., Marolda R., Ciafrè S., Ciotti MT., Mercanti D., Calissano P.</attribute>
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                    <attribute name="imex curation" nameAc="MI:0959"/>
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                    <shortLabel>matrone-2009-3</shortLabel>
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                            <shortLabel>rat</shortLabel>
                            <fullName>Rattus norvegicus (Rat)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
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                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
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                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                    <xref>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Matrone C., Marolda R., Ciafrè S., Ciotti MT., Mercanti D., Calissano P.</attribute>
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                    <attribute name="publication year" nameAc="MI:0886">2009</attribute>
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                    <attribute name="title" nameAc="MI:1091">Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation.</attribute>
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                    <attribute name="imex curation" nameAc="MI:0959"/>
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                    <shortLabel>matrone-2009-4</shortLabel>
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                            <shortLabel>rat</shortLabel>
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                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
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                        <shortLabel>anti bait coip</shortLabel>
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                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                    <attribute name="author-list" nameAc="MI:0636">Matrone C., Marolda R., Ciafrè S., Ciotti MT., Mercanti D., Calissano P.</attribute>
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                    <attribute name="publication year" nameAc="MI:0886">2009</attribute>
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                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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        <interactorList>
            <interactor id="3193219">
                <names>
                    <shortLabel>tnr16_rat</shortLabel>
                    <fullName>Tumor necrosis factor receptor superfamily member 16</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ngfr</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Tnfrsf16</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Low-affinity nerve growth factor receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Gp80-LNGFR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p75 ICD</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Low affinity neurotrophin receptor p75NTR</alias>
                </names>
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                    <secondaryRef db="rgd" dbAc="MI:0483" id="3177"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_198"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-205025" version="SP_198"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-193692" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000463" secondary="positive regulation of excitatory postsynaptic potential" version="SP_198"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2MIC" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005168" secondary="neurotrophin TRKA receptor binding" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007411" secondary="axon guidance" version="SP_198"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-209560" version="SP_198"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-205017" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000179" secondary="positive regulation of neural precursor cell proliferation" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" secondary="amyloid-beta binding" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" secondary="nuclear envelope" version="SP_198"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-205043" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005035" secondary="death receptor activity" version="SP_198"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_036742.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900182" secondary="positive regulation of protein localization to nucleus" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042488" secondary="positive regulation of odontogenesis of dentin-containing tooth" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010977" secondary="negative regulation of neuron projection development" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030336" secondary="negative regulation of cell migration" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016525" secondary="negative regulation of angiogenesis" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021675" secondary="nerve development" version="SP_198"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P07174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000377" secondary="regulation of reactive oxygen species metabolic process" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001235" secondary="positive regulation of apoptotic signaling pathway" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031643" secondary="positive regulation of myelination" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070678" secondary="preprotein binding" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_198"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BUK" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901216" secondary="positive regulation of neuron death" version="SP_198"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SG1" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016048" secondary="detection of temperature stimulus" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009611" secondary="response to wounding" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031069" secondary="hair follicle morphogenesis" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045334" secondary="clathrin-coated endocytic vesicle" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005911" secondary="cell-cell junction" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030426" secondary="growth cone" version="SP_198"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001368" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035025" secondary="positive regulation of Rho protein signal transduction" version="SP_198"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-209563" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0040037" secondary="negative regulation of fibroblast growth factor receptor signaling pathway" version="SP_198"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000488" version="SP_198"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_198"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045666" secondary="positive regulation of neuron differentiation" version="SP_198"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MRRAGAACSAMDRLRLLLLLILGVSSGGAKETCSTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDNVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCAYGYYQDEETGHCEACSVCEVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECEEIPGRWIPRSTPPEGSDSTAPSTQEPEVPPEQDLVPSTVADMVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEKLHSDSGISVDSQSLHDQQTHTQTASGQALKGDGNLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCSESTATSPV</sequence>
            </interactor>
            <interactor id="3193220">
                <names>
                    <shortLabel>ntrk1_rat</shortLabel>
                    <fullName>High affinity nerve growth factor receptor</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Neurotrophic tyrosine kinase receptor type 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p140-TrkA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Slow nerve growth factor receptor</alias>
                    <alias typeAc="MI:0301" type="gene name">Ntrk1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Trk</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Trka</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P35739" version="SP_77" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060384" secondary="innervation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_205"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-5716N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032675" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-177504" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048485" secondary="sympathetic nervous system development" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000139" secondary="Golgi membrane" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031901" secondary="early endosome membrane" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010465" secondary="nerve growth factor receptor activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038180" secondary="nerve growth factor signaling pathway" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" secondary="neuronal cell body" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" secondary="aging" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004675" secondary="transmembrane receptor protein serine/threonine kinase activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009314" secondary="response to radiation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050965" secondary="detection of temperature stimulus involved in sensory perception of pain" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990090" secondary="cellular response to nerve growth factor stimulus" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020461" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005166" secondary="neurotrophin p75 receptor binding" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030183" secondary="B cell differentiation" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008266" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046579" secondary="positive regulation of Ras protein signal transduction" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002011" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048678" secondary="response to axon injury" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060385" secondary="axonogenesis involved in innervation" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050966" secondary="detection of mechanical stimulus involved in sensory perception of pain" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014068" secondary="positive regulation of phosphatidylinositol 3-kinase signaling" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051602" secondary="response to electrical stimulus" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071316" secondary="cellular response to nicotine" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010976" secondary="positive regulation of neuron projection development" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001611" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-198203" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007611" secondary="learning or memory" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018108" secondary="peptidyl-tyrosine phosphorylation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051965" secondary="positive regulation of synapse assembly" version="SP_205"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_067600.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048011" secondary="neurotrophin TRK receptor signaling pathway" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019233" secondary="sensory perception of pain" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010623" secondary="programmed cell death involved in cell development" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004713" secondary="protein tyrosine kinase activity" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020635" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031902" secondary="late endosome membrane" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001245" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043547" secondary="positive regulation of GTPase activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005004" secondary="GPI-linked ephrin receptor activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048406" secondary="nerve growth factor binding" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007169" secondary="transmembrane receptor protein tyrosine kinase signaling pathway" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007399" secondary="nervous system development" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055038" secondary="recycling endosome membrane" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046777" secondary="protein autophosphorylation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021553" secondary="olfactory nerve development" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000018961" version="SP_205" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031410" secondary="cytoplasmic vesicle" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061368" secondary="behavioral response to formalin induced pain" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-170984" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051599" secondary="response to hydrostatic pressure" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020777" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043068" secondary="positive regulation of programmed cell death" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019900" secondary="kinase binding" version="SP_205"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P35739" version="SP_205"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976667" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071363" secondary="cellular response to growth factor stimulus" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038083" secondary="peptidyl-tyrosine autophosphorylation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043524" secondary="negative regulation of neuron apoptotic process" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031635" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055037" secondary="recycling endosome" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-170968" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005770" secondary="late endosome" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007623" secondary="circadian rhythm" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" secondary="early endosome" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000018961" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007411" secondary="axon guidance" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030425" secondary="dendrite" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042490" secondary="mechanoreceptor differentiation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043121" secondary="neurotrophin binding" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035094" secondary="response to nicotine" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051896" secondary="regulation of protein kinase B signaling" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051968" secondary="positive regulation of synaptic transmission, glutamatergic" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000013953" version="SP_205" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004714" secondary="transmembrane receptor protein tyrosine kinase activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901215" secondary="negative regulation of neuron death" version="SP_205"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="620144"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031667" secondary="response to nutrient levels" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060009" secondary="Sertoli cell development" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005030" secondary="neurotrophin receptor activity" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-187042" version="SP_205"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MLRGQRHGQLGWHRPAAGLGGLVTSLMLACACAASCRETCCPVGPSGLRCTRAGTLNTLRGLRGAGNLTELYVENQRDLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFHFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALLWLQRWEQEDLCGVYTQKLQGSGSGDQFLPLGHNNSCGVPSVKIQMPNDSVEVGDDVFLQCQVEGQALQQADWILTELEGTATMKKSGDLPSLGLTLVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGKAVEQHHWCIPFSVDGQPAPSLRWFFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG</sequence>
            </interactor>
            <interactor id="3193221">
                <names>
                    <shortLabel>psn1_rat</shortLabel>
                    <fullName>Presenilin-1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Psen1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Psnl1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein S182</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P97887" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" secondary="early endosome" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005640" secondary="nuclear outer membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050808" secondary="synapse organization" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060075" secondary="regulation of resting membrane potential" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045296" secondary="cadherin binding" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099056" secondary="integral component of presynaptic membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001756" secondary="somitogenesis" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060828" secondary="regulation of canonical Wnt signaling pathway" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098712" secondary="L-glutamate import across plasma membrane" version="SP_183"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-3928665" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097060" secondary="synaptic membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043005" secondary="neuron projection" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001568" secondary="blood vessel development" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010467" secondary="gene expression" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005765" secondary="lysosomal membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050852" secondary="T cell receptor signaling pathway" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032469" secondary="endoplasmic reticulum calcium ion homeostasis" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044267" secondary="cellular protein metabolic process" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002038" secondary="positive regulation of L-glutamate import across plasma membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042982" secondary="amyloid precursor protein metabolic process" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006914" secondary="autophagy" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015031" secondary="protein transport" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051208" secondary="sequestering of calcium ion" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021870" secondary="Cajal-Retzius cell differentiation" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" secondary="beta-catenin binding" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003407" secondary="neural retina development" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010975" secondary="regulation of neuron projection development" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000186" secondary="activation of MAPKK activity" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016080" secondary="synaptic vesicle targeting" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043011" secondary="myeloid dendritic cell differentiation" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048167" secondary="regulation of synaptic plasticity" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016235" secondary="aggresome" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070851" secondary="growth factor receptor binding" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022008" secondary="neurogenesis" version="SP_183"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48909N"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009791" secondary="post-embryonic development" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000139" secondary="Golgi membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050435" secondary="amyloid-beta metabolic process" version="SP_183"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="3425"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070765" secondary="gamma-secretase complex" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000045" secondary="autophagosome assembly" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031901" secondary="early endosome membrane" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031594" secondary="neuromuscular junction" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001708" secondary="cell fate specification" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048538" secondary="thymus development" version="SP_183"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-193692" version="SP_183"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000012495" version="SP_183" refType="transcript"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007613" secondary="memory" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042462" secondary="eye photoreceptor cell development" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051966" secondary="regulation of synaptic transmission, glutamatergic" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" secondary="positive regulation of tumor necrosis factor production" version="SP_183"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MTEIPAPLSYFQNAQMSEDSHSSSVRSQNDNQERQQHHDRQRLDNPESISNGRPQSNFTRQVIEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIVSSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVPKNPKYSTQGTEREETQDTGTGSDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSGSILTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATDYLVQPFMDQLAFHQFYI</sequence>
            </interactor>
            <interactor id="3193222">
                <names>
                    <shortLabel>a4_rat</shortLabel>
                    <fullName>Amyloid-beta precursor protein</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Alzheimer disease amyloid A4 protein homolog</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ABPP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloidogenic glycoprotein</alias>
                    <alias typeAc="MI:0301" type="gene name">App</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloid precursor protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">A4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">AD1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Alzheimer disease amyloid protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloid-beta (A4) precursor protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloid-beta A4 protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P08592" version="SP_105" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_238"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_238"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030134" secondary="COPII-coated ER to Golgi transport vesicle" version="SP_238"/>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
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        <interactionList>
            <interaction imexId="IM-14756-1" id="3193223">
                <names>
                    <shortLabel>ntrk1-ngfr-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-9790E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14756-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15790489" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3193215</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3193224">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790494" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3193225">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790493" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193220</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-14756-2" id="3193226">
                <names>
                    <shortLabel>ngfr-psen1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-103969E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15790506" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14756-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3193216</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3193227">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790511" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193221</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="3193228">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790510" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-14756-3" id="3193229">
                <names>
                    <shortLabel>ngfr-ntrk1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-9790E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14756-3" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15790523" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3193217</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3193230">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790528" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193220</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3193231">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790527" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-14756-4" id="3193232">
                <names>
                    <shortLabel>app-ngfr-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-103968E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15790540" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14756-4" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3193218</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3193233">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790545" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3193234">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15790544" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3193222</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
