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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3190495">
                <names>
                    <shortLabel>ito-2009-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="19429709" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-134225X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14729" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0900064106" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15779679" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse</shortLabel>
                            <fullName>Mus musculus</fullName>
                            <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ito K., Akazawa H., Tamagawa M., Furukawa K., Ogawa W., Yasuda N., Kudo Y., Liao CH., Yamamoto R., Sato T., Molkentin JD., Kasuga M., Noda T., Nakaya H., Komuro I.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-134225X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2009</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">PDK1 coordinates survival pathways and beta-adrenergic response in the heart.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Ito K.,  Akazawa H.,  Tamagawa M.,  Furukawa K.,  Ogawa W.,  Yasuda N.,  Kudo Y.,  Liao CH.,  Yamamoto R.,  Sato T.,  Molkentin JD.,  Kasuga M.,  Noda T.,  Nakaya H.,  Komuro I.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3190496">
                <names>
                    <shortLabel>pk3cg_mouse</shortLabel>
                    <fullName>Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">p120-PI3K</alias>
                    <alias typeAc="MI:0301" type="gene name">Pik3cg</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Pi3kg1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Phosphoinositide-3-kinase catalytic gamma polypeptide</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Serine/threonine protein kinase PIK3CG</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9JHG7" version="SP_56" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000270" secondary="negative regulation of fibroblast apoptotic process" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035022" secondary="positive regulation of Rac protein signal transduction" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003376" secondary="sphingosine-1-phosphate receptor signaling pathway" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097284" secondary="hepatocyte apoptotic process" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000062864" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000085469" version="SP_179" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036940" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106310" secondary="protein serine kinase activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043085" secondary="positive regulation of catalytic activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0052812" secondary="phosphatidylinositol-3,4-bisphosphate 5-kinase activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010897" secondary="negative regulation of triglyceride catabolic process" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006515175.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016310" secondary="phosphorylation" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016303" secondary="1-phosphatidylinositol-3-kinase activity" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000082596" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0052742" secondary="phosphatidylinositol kinase activity" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000020573" version="SP_179" refType="gene"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-41862N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006897" secondary="endocytosis" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032252" secondary="secretory granule localization" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001139673.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002376" secondary="immune system process" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007186" secondary="G protein-coupled receptor signaling pathway" version="SP_179"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9027276" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000220366" version="SP_179" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016024" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048015" secondary="phosphatidylinositol-mediated signaling" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016301" secondary="kinase activity" version="SP_179"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q80V09" version="SP_87" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001263" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903169" secondary="regulation of calcium ion transmembrane transport" version="SP_179"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-644372" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035005" secondary="1-phosphatidylinositol-4-phosphate 3-kinase activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007204" secondary="positive regulation of cytosolic calcium ion concentration" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR042236" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043406" secondary="positive regulation of MAP kinase activity" version="SP_179"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-392451" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002420" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000053215" version="SP_179" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-114604" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051897" secondary="positive regulation of protein kinase B signaling" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000403" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015433" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106311" secondary="protein threonine kinase activity" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005943" secondary="phosphatidylinositol 3-kinase complex, class IA" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029071" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005942" secondary="phosphatidylinositol 3-kinase complex" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000341" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046934" secondary="phosphatidylinositol-4,5-bisphosphate 3-kinase activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071320" secondary="cellular response to cAMP" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010595" secondary="positive regulation of endothelial cell migration" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000123539" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005944" secondary="phosphatidylinositol 3-kinase complex, class IB" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035892" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" secondary="angiogenesis" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046854" secondary="phosphatidylinositol phosphate biosynthetic process" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014065" secondary="phosphatidylinositol 3-kinase signaling" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000151400" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003113" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006935" secondary="chemotaxis" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036092" secondary="phosphatidylinositol-3-phosphate biosynthetic process" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000156904" version="SP_179" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002675" secondary="positive regulation of acute inflammatory response" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018936" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_064668.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046875" secondary="ephrin receptor binding" version="SP_179"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1660499" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001932" secondary="regulation of protein phosphorylation" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001139672.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLHVAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLDCLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRLVTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNGDEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKIKDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDYVLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLPESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA</sequence>
            </interactor>
            <interactor id="3190497">
                <names>
                    <shortLabel>arbk1_mouse</shortLabel>
                    <fullName>Beta-adrenergic receptor kinase 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Grk2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Adrbk1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">G-protein-coupled receptor kinase 2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q99MK8" version="SP_52" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001277747.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011993" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000239" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008271" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007507" secondary="heart development" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018105" secondary="peptidyl-serine phosphorylation" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036305" version="SP_175"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-32413N"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001849" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043198" secondary="dendritic shaft" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045907" secondary="positive regulation of vasoconstriction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045744" secondary="negative regulation of G protein-coupled receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046718" secondary="viral entry into host cell" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048709" secondary="oligodendrocyte differentiation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" secondary="protein kinase activity" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016137" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010661" secondary="positive regulation of muscle cell apoptotic process" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019079" secondary="viral genome replication" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901081" secondary="negative regulation of relaxation of smooth muscle" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010801" secondary="negative regulation of peptidyl-threonine phosphorylation" version="SP_175"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q99MK8" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-418555" version="SP_175"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031850" secondary="delta-type opioid receptor binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007186" secondary="G protein-coupled receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018107" secondary="peptidyl-threonine phosphorylation" version="SP_175"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000024858" version="SP_175" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990869" secondary="cellular response to chemokine" version="SP_175"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000086114" version="SP_175" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000088737" version="SP_175" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002026" secondary="regulation of the force of heart contraction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047696" secondary="beta-adrenergic receptor kinase activity" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005929" secondary="cilium" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048146" secondary="positive regulation of fibroblast proliferation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002029" secondary="desensitization of G protein-coupled receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009966" secondary="regulation of signal transduction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071364" secondary="cellular response to epidermal growth factor stimulus" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004703" secondary="G protein-coupled receptor kinase activity" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007217" secondary="tachykinin receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046325" secondary="negative regulation of glucose import" version="SP_175"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-771762" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071333" secondary="cellular response to glucose stimulus" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051457" secondary="maintenance of protein location in nucleus" version="SP_175"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q99LL8" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001664" secondary="G protein-coupled receptor binding" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8856825" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043197" secondary="dendritic spine" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031755" secondary="Edg-2 lysophosphatidic acid receptor binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000463" secondary="positive regulation of excitatory postsynaptic potential" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904058" secondary="positive regulation of sensory perception of pain" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-416476" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5635838" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006979" secondary="response to oxidative stress" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904707" secondary="positive regulation of vascular associated smooth muscle cell proliferation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003108" secondary="negative regulation of the force of heart contraction by chemical signal" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014070" secondary="response to organic cyclic compound" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060048" secondary="cardiac muscle contraction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042699" secondary="follicle-stimulating hormone signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031851" secondary="kappa-type opioid receptor binding" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000961" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106072" secondary="negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900077" secondary="negative regulation of cellular response to insulin stimulus" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033605" secondary="positive regulation of catecholamine secretion" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042311" secondary="vasodilation" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005901" secondary="caveola" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031623" secondary="receptor internalization" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045988" secondary="negative regulation of striated muscle contraction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674" secondary="protein serine/threonine kinase activity" version="SP_175"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLETEEERVVRSREIFDSYIMKELLACSHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIVHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLIQRGSANGL</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-14729-1" id="3190498">
                <names>
                    <shortLabel>grk2-pik3cg-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-103826E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14729-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15779690" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3190495</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3190499">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15779695" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3190496</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3190500">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15779694" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3190497</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
