DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ kim-2008-19 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113203X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation kim-2008-20 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113208X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation kim-2008-21 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113206X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation kim-2008-22 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113204X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation kim-2008-23 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113209X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation kim-2008-24 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113207X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation kim-2008-25 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. DIP original experiment: DIP-113205X Structure (London, England : 1993) 2008 IMEx Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Kim EY., Rumpf CH., Fujiwara Y., Cooley ES., Van Petegem F., Minor DL. Only protein-protein interactions imex curation calm_human Calmodulin CALM1 CALM CAM CAM1 CALM2 CAMB CALM3 CAM3 CAMC CAMIII CAM2 CALML2 protein protein human Homo sapiens Human MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK cac1a_rabit Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A CACH4 CACN3 CACNL1A4 Brain calcium channel I Calcium channel, L type, alpha-1 polypeptide isoform 4 Voltage-gated calcium channel subunit alpha Cav2.1 protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MARFGDEMPARYGGGGAGAAAGVVVGAAGGRGAGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTRCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDVEQRHPFDGALRRATIKKSKTDLLHPEEAEDQLADIASVGSPFARASIKSAKLENSSFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAVNQKLALQKAKEVAEVSPLSAANMSIAMKEQQKNQKPAKSVWEQRTSEMRKQNLLASREALYSEMDPEERWKASYARHLRPDMKTHLDRPLVVDPQENRNNNTNKSRVAEPTVDQRLGQQRAEDFLRKQARHHDRARDPSAHAAAGLDARRPWAGSQEAELSREGPYGRESDHQAREGGLEPPGFWEGEAERGKAGDPHRRHAHRQGVGGSGGSRSGSPRTGTADGEPRRHRVHRRPGEDGPDDKAERRGRHREGSRPARSGEGEAEGPDGGGGGGGERRRRHRHGPPPAYDPDARRDDRERRHRRRKDTQGSGVPVSGPNLSTTRPIQQDLSRQEPPLAEDMDNLKNSRLATAEPVSPHENLSHAGLPQSPAKMGSSTDPAGPTPATAANPQNSTASRRTPNNPGNPSNPGPPKTPENSLIVTNPSTAQTNSAKTARKPDHTTVEIPPACPPPLNHTVVQVNKNANPDPLPKKEDEKKEEVDEGPGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMPQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYDNALKVFNIVFTSLFSLECLLKVLAFGILNYFRDAWNIFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDMEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGILTPECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAAWGRMLYRDMYAMLRHMPPPLGLGKNCPARVAYKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAMREEQNRTPLMFQRMEPPPDEGGAGQNALPSTQLDPAGGLMAHEDGLKDSPSWVTQRAQEMFQKTGTWSPERAPPADMADSQPKPQSVEMREMSQDGYSDSEHCLPMEGQARAASMPRLPAENQRRRGRPRGSDLSTICDTSPMKRSASVLGPKASRRLDDYSLERVPPEENQRHHPRRRERAHRTSERSLGRYTDVDTGLGTDLSMTTQSGDLPSREREQERGRPKDRKHRPHHHHHHHHHPGRGPGRVSPGVSARRRRRGPVARVRPARAPALAHARARARAPARLLPELRLRRARRPRPRQRRRPRRRRGGGGRALRRAPGPREPLAQDSPGRGPSVCLARAARPAGPQRLLPGPRTGQAPRARLPQKPARSVQRERRGLVLSPPPPPPGELAPRAHPARTPRPGPGDSRSRRGGRRWTASAGKGGGGPRASAPSP cac1e_rat Voltage-dependent R-type calcium channel subunit alpha-1E Cacna1e Cach6 Cacnl1a6 BII Brain calcium channel II Calcium channel, L type, alpha-1 polypeptide, isoform 6 RBE-II RBE2 Voltage-gated calcium channel subunit alpha Cav2.3 protein protein rat Rattus norvegicus (Rat) Rat MALYNPIPVRQNCFTVNRSLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNSGTSALEVLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSTKVDGASYFRHKERLLRISIRHMVKSQVFYWIVLSVVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRFNFNDGTPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAFNQKHALQKAKEVSPMSAPNMPSIERDRRRRHHMSMWEPRSSHLRERRRRHHMSVWEQRTSQLRRHMQMSSQEALNKEEAPPMNPLNPLNPLSPLNPLNAHPSLYRRPRPIEGLALGLGLEKCEEERISRGGSLKGDIGGLTSVLDNQRSPLSLGKREPPWLPRSCHGNCDPTQQETGGGETVVTFEDRARHRQSQRRSRHRRVRTEGKESASASRSRSASQERSLDEGVSIDGEKEHEPQSSHRSKEPTIHEEERTQDLRRTNSLMVPRGSGLVGALDEAETPLVQPQPELEVGKDAALTEQEAEGSSEQALLADVQLDVGRGISQSEPDLSCMTTNMDKATTESTSVTVAIPDVDPLVDSTVVNISNKTDGEASPLKEAETKEEEEEVEKKKQKKEKRETGKAMVPHSSMFIFSTTNPIRKACHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDTEKECIGNYVDHEKNKMEVKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKNERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSAPWTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILTDSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGCEPDTTAPSGQNESERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRVWAEYDRAACGRIHYTEMYEMLTLMSPPLGLGKRCPSKVAYKRLVLMNMPVAEDMTVHFTSTLMALIRTALDIKIAKGGADRQQLDSELQKETLAIWPHLSQKMLDLLVPMPKASDLTVGKIYAAMMIMDYYKQSKVKKQRQQLEEQKNAPMFQRMEPSSLPQEIISNAKALPYLQQDPVSGLSGRSGYPSMSPLSPQEIFQLACMDPADDGQFQEQQSLVVTDPSSMRRSFSTIRDKRSNSSWLEEFSMERSSENTYKSRRRSYHSSLRLSAHRLNSDSGHKSDTHRSGGRERGRSKERKHLLSPDVSRCNSEERGTQADWESPERRQSRSPSEGRSQTPNRQGTGSLSESSIPSISDTSTPRRSRRQLPPVPPKPRPLLSYSSLMRHTGGISPPPDGSEGGSPLASQALESNSACLTESSNSLHPQQGQHPSPQHYISEPYLALHEDSHASDCGEEETLTFEAAVATSLGRSNTIGSAPPLRHSWQMPNGHYRRRRLGGLGLAMMCGAVSDLLSDTEEDDKC cac1b_rabit Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B CACH5 CACNL1A5 Brain calcium channel III Calcium channel, L type, alpha-1 polypeptide isoform 5 Voltage-gated calcium channel subunit alpha Cav2.2 protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MVRFGDELGGRYGGAGGAERARGGGAGGAGGPGPGGLPPGQRVLYKQSIAQRARTMALYNPIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKILALGFVLHKGSYLRNGWNVMDFVVVLTGILATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDPDPVGDFPCGKEAPARLCEGDTECREYWAGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRAAAKKSRSDLIQAEEGEGRLTGLCAPGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVKAQSFYWTVLCVVALNTLCVAMVHYNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSIFEVVWAAVKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFKDETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVSRGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRYATARHLRPDVKTHLDRPLVVEPGRDAPRGPPGGKSRPDGSEAPEGADPPRRHHRHRDKDKAPATVPSAGEQDRAEALRAEGGELGPREERGRPRRSRSKEAPGAPEVRSDRGRGPCPEGGRRHHRRGSPEEAAEREPRRHRAHRHGPDPGKEGPASGTRGERRARHRTGPRACPREAESSEEPARRHRARHKAPPTQETAEKDKEAAEKGGEATEAEKDKEARNHQPKELPCDLEAIGMLGVGAVHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDTSTTVHIPVTLTGPPGETTVVPSGNVDLESQAEGKKEVETSDVMRSGPRPIVPYSSMFCLSPTNLLRRCCHYIVTMRYFEMVILVVIALSSIALAAEDPVRTDSPRNNALKYMDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDISTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISARPLTRYMPQNKQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIANNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSSRACDEHSNASECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYSDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISSEDMTVHFTSTLMALIRTALDIKLAPAGTKQHQCDAELRKEISCVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTSRDQTQQAPGGLSQLGPVSLFHPLKATLEQTQPALRGARAFLRQKSSASLSNGGAVQTQESGIKESVSWGTQRTQDVLCEARAPLERGHSAEIPVGQPGTLAVDVQMQNMTLSGPDAEPQPGLESQGRAASMPRLAAETQPAPDASPMKRSISTLAPRPHTARLGSTALDRPAPSQAPHHHHHRCHRRRDRKQRSLEKGPSLSADTDGAPDSTVGPGLPTGEGPPGCRRERERRQERGRSQERRQPSSSSSEKHRFYSCDRFGGREPPQPKPSLSSHPTSPTAGQEPGPHPQGSGSVHGSPLLSTSGASTPGRGRRQLPQTPLTPRPSVTYKTANSSPVHFAGAPSGLPAFSPGRLSRGLSEHNALLQRDPLSRPLAPGSRIGSDPYLGQRLDSEAPARALPEDAPAFEETAASNSGRSSRTSYVSSLTSQPPPLRRVPNGYHCTLGLGGGGRARRGCHHPDRDRRC cacna1a-calm1-1 3178643 N/A 3178650 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3178651 unspecified role unspecified role unspecified role unspecified role Region 1963-1984 Region 1963-1984 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cacna1e-calm1-1 3178644 N/A 3178652 unspecified role unspecified role unspecified role unspecified role Region 1818-1839 Region 1818-1839 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3178650 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false cacna1b-calm1-1 3178645 N/A 3178653 unspecified role unspecified role unspecified role unspecified role Region 1855-1876 Region 1855-1876 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3178650 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false cacna1a-calm1-2 3178646 N/A 3178650 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3178651 unspecified role unspecified role unspecified role unspecified role Region 1963-1984 Region 1963-1984 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cacna1a-calm1-3 3178647 N/A 3178650 unspecified role unspecified role unspecified role unspecified role Region 2-79 Region 2-79 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Region 80-149 Region 80-149 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3178651 unspecified role unspecified role unspecified role unspecified role Region 1961-1987 Region 1961-1987 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false P27884:p.Tyr1974Ala Y1974A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false P27884:p.Met1970Ala M1970A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cacna1e-calm1-2 3178648 N/A 3178652 unspecified role unspecified role unspecified role unspecified role Region 1818-1839 Region 1818-1839 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3178650 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false cacna1b-calm1-2 3178649 N/A 3178653 unspecified role unspecified role unspecified role unspecified role Region 1855-1876 Region 1855-1876 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3178650 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false