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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3178353">
                <names>
                    <shortLabel>niizuma-2008-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18845684" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-133404X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14341" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0806222105" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732788" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10116">
                        <names>
                            <shortLabel>rat</shortLabel>
                            <fullName>Rattus norvegicus (Rat)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Niizuma K., Endo H., Nito C., Myer DJ., Kim GS., Chan PH.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-133404X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">The PIDDosome mediates delayed death of hippocampal CA1 neurons after transient global cerebral ischemia in rats.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Niizuma K.,  Endo H.,  Nito C.,  Myer DJ.,  Kim GS.,  Chan PH.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3178354">
                <names>
                    <shortLabel>niizuma-2008-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18845684" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-133405X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14341" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0806222105" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732907" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10116">
                        <names>
                            <shortLabel>rat</shortLabel>
                            <fullName>Rattus norvegicus (Rat)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Niizuma K., Endo H., Nito C., Myer DJ., Kim GS., Chan PH.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-133405X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">The PIDDosome mediates delayed death of hippocampal CA1 neurons after transient global cerebral ischemia in rats.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Niizuma K.,  Endo H.,  Nito C.,  Myer DJ.,  Kim GS.,  Chan PH.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3178355">
                <names>
                    <shortLabel>casp2_rat</shortLabel>
                    <fullName>Caspase-2</fullName>
                    <alias typeAc="MI:0301" type="gene name">Casp2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ich1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protease ICH-1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P55215" version="93" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" secondary="cellular response to mechanical stimulus" version="SP_178"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9WUI6" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732853" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015917" version="SP_178"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000016707" version="SP_178" refType="gene"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48602N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000022672" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" secondary="aging" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043525" secondary="positive regulation of neuron apoptotic process" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016129" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016485" secondary="protein processing" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" secondary="proteolysis" version="SP_178"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_071967.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004197" secondary="cysteine-type endopeptidase activity" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001309" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006977" secondary="DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_178"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-6803207" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029030" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001554" secondary="luteolysis" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097199" secondary="cysteine-type endopeptidase activity involved in apoptotic signaling pathway" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035702" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" secondary="apoptotic signaling pathway" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033139" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_178"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-168638" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0012501" secondary="programmed cell death" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002138" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_178"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000022672" version="SP_178" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-205025" version="SP_178"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001315" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007420" secondary="brain development" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003407" secondary="neural retina development" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097153" secondary="cysteine-type endopeptidase activity involved in apoptotic process" version="SP_178"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O35398" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002398" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001235" secondary="positive regulation of apoptotic signaling pathway" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008630" secondary="intrinsic apoptotic signaling pathway in response to DNA damage" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097192" secondary="extrinsic apoptotic signaling pathway in absence of ligand" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097200" secondary="cysteine-type endopeptidase activity involved in execution phase of apoptosis" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035234" secondary="ectopic germ cell programmed cell death" version="SP_178"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O55194" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="69274"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MAASSGRSQSSLHRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTTLSDIQHILPPLSCDYDSSLPFSVCESCPPHKQSRLSTDTMEHSLDNGDGPPCLQVKPCTPEFYQAHYQLAYRLQSQPRGLALVMSNVHFTGEKDLEFRSGGDVDHTTLVTLFKLLGYNVHVLYDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGGIYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAQSPGCEESDAGKEELMKMRLPTRSDMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTEFHRCKEMSEYCSTLCQQLYLFPGYPPT</sequence>
            </interactor>
            <interactor id="3178356">
                <names>
                    <shortLabel>d3zb14_rat</shortLabel>
                    <alias typeAc="MI:0301" type="gene name">Cradd</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cradd_predicted</alias>
                    <alias typeAc="MI:0306" type="orf name">rCG_48999</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="D3ZB14" version="4" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000008507" version="TrEMBL_79" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="TrEMBL_79"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001315" version="TrEMBL_79"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="TrEMBL_79"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-6803207" version="TrEMBL_79"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48601N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006977" secondary="DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest" version="TrEMBL_79"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030674" secondary="protein-macromolecule adaptor activity" version="TrEMBL_79"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="TrEMBL_79"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" secondary="apoptotic signaling pathway" version="TrEMBL_79"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000063946" version="TrEMBL_79" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" secondary="cellular response to mechanical stimulus" version="TrEMBL_79"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="TrEMBL_79"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR042148" version="TrEMBL_79"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="1311010"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="TrEMBL_79"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001101555.1"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732828" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037939" version="TrEMBL_79"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" secondary="protease binding" version="TrEMBL_79"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070513" secondary="death domain binding" version="TrEMBL_79"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000062865" version="TrEMBL_79" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001235" secondary="positive regulation of apoptotic signaling pathway" version="TrEMBL_79"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MDARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEIKAQTTGLRKTMLLLDILPSRGPKAFDTFLDSLQEFPWVREKLEKAREEATAELPTAQPRKDHLPEKPFIIRLITAAPREAAPESLSPVAETAQSGQKGRLDQSNSCPSAPVAATEACLDQS</sequence>
            </interactor>
            <interactor id="3178357">
                <names>
                    <shortLabel>d3zzy5_rat</shortLabel>
                    <alias typeAc="MI:0301" type="gene name">Pidd1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">LOC100911519</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="D3ZZY5" version="4" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000025291" version="TrEMBL_97" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097191" secondary="extrinsic apoptotic signaling pathway" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="TrEMBL_97"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732799" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043122" secondary="regulation of I-kappaB kinase/NF-kappaB signaling" version="TrEMBL_97"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032675" version="TrEMBL_97"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_008772966.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000018710" version="TrEMBL_97" refType="gene"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_003749059.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001611" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016540" secondary="protein autoprocessing" version="TrEMBL_97"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001099788.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" secondary="cellular response to DNA damage stimulus" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="TrEMBL_97"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-6803207" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006977" secondary="DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="TrEMBL_97"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48600N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008625" secondary="extrinsic apoptotic signaling pathway via death domain receptors" version="TrEMBL_97"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="TrEMBL_97"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="6492303"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019502" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" secondary="apoptotic signaling pathway" version="TrEMBL_97"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003591" version="TrEMBL_97"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004175" secondary="endopeptidase activity" version="TrEMBL_97"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000065320" version="TrEMBL_97" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000025290" version="TrEMBL_97" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000488" version="TrEMBL_97"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000049179" version="TrEMBL_97" refType="gene"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="1311792"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000906" version="TrEMBL_97"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000072774" version="TrEMBL_97" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MAAVLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLAGNQLNLDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLLSHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEIGDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLRDNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHGVAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKRRWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGLELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVPEEAEAARRRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQPGAVGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPESAQA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-14341-1" id="3178358">
                <names>
                    <shortLabel>pidd1-casp2-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-103272E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732900" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14341-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3178353</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3178359">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732906" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178355</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3178360">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732905" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178356</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3178361">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732904" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178357</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-14341-2" id="3178362">
                <names>
                    <shortLabel>casp2-cradd-9</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-103272E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732918" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-14341-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3178354</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3178363">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732924" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178355</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3178364">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732923" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178356</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3178365">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732922" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178357</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10116">
                                <names>
                                    <shortLabel>rat</shortLabel>
                                    <fullName>Rattus norvegicus (Rat)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rat</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
