DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ penna-2008-1 drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249965X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation penna-2008-2 drome Drosophila melanogaster (Fruit fly) Fruit fly crosslink cross-linking study crosslink anti tag western anti tag western blot anti tag western Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249967X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation penna-2008-3 drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249963X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation penna-2008-4 drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249964X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation penna-2008-5 drome Drosophila melanogaster (Fruit fly) Fruit fly crosslink cross-linking study crosslink anti tag western anti tag western blot anti tag western Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249968X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation penna-2008-6 drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249966X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation penna-2008-7 drome Drosophila melanogaster (Fruit fly) Fruit fly crosslink cross-linking study crosslink anti tag western anti tag western blot anti tag western Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. DIP original experiment: DIP-249969X Nature 2008 IMEx The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Penna A., Demuro A., Yeromin AV., Zhang SL., Safrina O., Parker I., Cahalan MD. Only protein-protein interactions imex curation stim_drome Stromal interaction molecule homolog Stim CG9126 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MRKNTIWNYSLIFFCCVLKSISTLDHGPHTVSVDSNRHNTQHQYKQNPNVASQRHSSHESGQSLHNSQSEHVTHIAASHAGSGGEHSTHLAQNLHRSSYNLLSEAMSQAVSNEFSSMGSGSADGACAADDFDCYSGSVQDRFGMEAIASLHRQLDDDDNGNIDLSESDDFLREELKYDSGYEKRQKAFHFNDDMHISVKELWEAWLRSEVHNWTIEQTTDWLAQSVQLPQYVDLFKLHKVTGAALPRLAVNNLQYVGNVLGIKDPIHKQKISLKAMDVVLFGPPRETGTRWKDYILVTLLLSAIIGCWYAYQQNKNAKRHLRRMAQDMEGLQRAEQSLQEMQKELERARMEQENVATEKLDLERRLKEAPTLSSSNSDLEVQQLKKEIEMLRNELSRAEFELVDNCWSPPPQLQSWLQYTYELESKNHQKKRTSAEKQLQSAREACEKLRKKRSSLVGAFVSTHGKSIDDVDRSIVEARNALGDVTNELQERLHRWKQIETCLGLNIVNNNGLPYLENVLYGRNGGLQSSMGMSSTKGSRARITNSTEDLDDESIQGKLNFENFSLLATE crcm1_drome Calcium release-activated calcium channel protein 1 Orai CRACM1 Protein orai olf186-F CG11430 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSVWTTANNSGLETPTKSPITSSVPRAARSSAVITTGNHQQHHFQHVVAAAVAAATSVATGHQFQQQFPLHAHPHPQHHSNSPTGSGSNSNNSAGFQRTSISNSLLQFPPPPPPSSQNQAKPRGHHRTASSSMSQSGEDLHSPTYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAICTTLLVAVHMLALMISTCILPNIETVCNLHSISLVHESPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSPPAAWSACVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHHNNIRNNGMNYGASGDIV olf186_f-stim-2 3177939 N/A 3177946 unspecified role unspecified role prey prey Region 315-570 Region 315-570 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false drome Drosophila melanogaster (Fruit fly) Fruit fly N/A 3177947 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association false false false olf186_f-1 3177940 N/A 3177947 unspecified role unspecified role unspecified role unspecified role HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly direct interaction direct interaction false false false olf186_f-olf186_f-1 3177941 N/A 3177947 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly N/A 3177947 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association false false false olf186_f-olf186_f-2 3177942 N/A 3177947 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly N/A 3177947 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association false false false stim-1 3177943 N/A 3177946 unspecified role unspecified role unspecified role unspecified role Region 315-570 Region 315-570 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false drome Drosophila melanogaster (Fruit fly) Fruit fly direct interaction direct interaction false false false stim-olf186_f-2 3177944 N/A 3177946 unspecified role unspecified role bait bait Region 315-570 Region 315-570 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false drome Drosophila melanogaster (Fruit fly) Fruit fly N/A 3177947 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly physical association physical association false false false olf186_f-2 3177945 N/A 3177947 unspecified role unspecified role unspecified role unspecified role Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false drome Drosophila melanogaster (Fruit fly) Fruit fly direct interaction direct interaction false false false