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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3175500">
                <names>
                    <shortLabel>cisneros-2008-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18682222" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-110809X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9291" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15719523" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1016/j.str.2008.04.014" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>atomic force microsc</shortLabel>
                        <fullName>atomic force microscopy</fullName>
                        <alias typeAc="MI:0303" type="go synonym">AFM</alias>
                        <alias typeAc="MI:1041" type="synonym">AFM</alias>
                        <alias typeAc="MI:1041" type="synonym">atomic force microsc</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0872" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="17502105" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1372321" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Cisneros DA., Oberbarnscheidt L., Pannier A., Klare JP., Helenius J., Engelhard M., Oesterhelt F., Muller DJ.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-110809X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Transducer binding establishes localized interactions to tune sensory rhodopsin II.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Cisneros DA.,  Oberbarnscheidt L.,  Pannier A.,  Klare JP.,  Helenius J.,  Engelhard M.,  Oesterhelt F.,  Muller DJ.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3175501">
                <names>
                    <shortLabel>htr2_natph</shortLabel>
                    <fullName>Sensory rhodopsin II transducer</fullName>
                    <alias typeAc="MI:0301" type="gene name">htr2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">htrII</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HTR-II</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Methyl-accepting phototaxis protein II</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P42259" version="SP_61" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_121"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_121"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003660" version="SP_121"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1034515" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_121"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009881" secondary="photoreceptor activity" version="SP_121"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004089" version="SP_121"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006935" secondary="chemotaxis" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H2S" version="SP_121"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004090" version="SP_121"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P42259"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RM8" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2F95" version="SP_121"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_121"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040913" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2F93" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJF" version="SP_121"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GYC" version="SP_121"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-35283N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018298" secondary="protein-chromophore linkage" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJE" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJJ" version="SP_121"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJN" version="SP_121"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="2257">
                    <names>
                        <shortLabel>natph</shortLabel>
                        <fullName>Natronomonas pharaonis (Natronobacterium pharaonis)</fullName>
                    </names>
                </organism>
                <sequence>MSLNVSRLLLPSRVRHSYTGKMGAVFIFVGALTVLFGAIAYGEVTAAAATGDAAAVQEAAVSAILGLIILLGINLGLVAATLGGDTAASLSTLAAKASRMGDGDLDVELETRREDEIGDLYAAFDEMRQSVRTSLEDAKNAREDAEQAQKRAEEINTELQAEAERFGEVMDRCADGDFTQRLDAETDNEAMQSIEGSFNEMMDGIEALVGRIERFADAVSEDAEAVRANAESVMEASEDVNRAVQNISDAAGDQTETVQQIALEMDDVSATTEEVAASADDIAKTARQAAETGEAGRETAETAITEMNEVESRTEQAVASMEELNEDVREIGEVSEMIADIAEQTNILALNASIEAARADGNSEGFAVVADEVKALAEETKAATEEIDDLIGTVQDRTQTTVDDIRETSDQVSEGVETVEDTVDALERIVDSVERTNDGIQEINQSTDAQADAAQKATTMVEDMAATSEQTASDAETAAETTETQAESVKEVFDLIDGLSEQADSLSETLSRTDTEEASAADLDDQPTLAAGDD</sequence>
            </interactor>
            <interactor id="3175502">
                <names>
                    <shortLabel>bacs2_natph</shortLabel>
                    <fullName>Sensory rhodopsin-2</fullName>
                    <alias typeAc="MI:0301" type="gene name">sop2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">sopII</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Sensory rhodopsin II</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P42196" version="SP_59" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018298" secondary="protein-chromophore linkage" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QAP" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H2S" version="SP_119"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018229" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007602" secondary="phototransduction" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJF" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJJ" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJE" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005216" secondary="ion channel activity" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2F93" version="SP_119"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-35282N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001425" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QDC" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JJN" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009881" secondary="photoreceptor activity" version="SP_119"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1034509" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JGJ" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GYC" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GUE" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GU8" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H68" version="SP_119"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2F95" version="SP_119"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="2257">
                    <names>
                        <shortLabel>natph</shortLabel>
                        <fullName>Natronomonas pharaonis (Natronobacterium pharaonis)</fullName>
                    </names>
                </organism>
                <sequence>MVGLTTLFWLGAIGMLVGTLAFAWAGRDAGSGERRYYVTLVGISGIAAVAYVVMALGVGWVPVAERTVFAPRYIDWILTTPLIVYFLGLLAGLDSREFGIVITLNTVVMLAGFAGAMVPGIERYALFGMGAVAFLGLVYYLVGPMTESASQRSSGIKSLYVRLRNLTVILWAIYPFIWLLGPPGVALLTPTVDVALIVYLDLVTKVGFGFIALDAAATLRAEHGESLAGVDTDAPAVAD</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-9291-1" id="3175503">
                <names>
                    <shortLabel>htr2-sop2-4</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-64056E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15719534" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9291-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3175500</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3175504">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15719539" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3175501</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3175505">
                                <names>
                                    <shortLabel>Region 1-114</shortLabel>
                                    <fullName>Region 1-114</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15719540" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="114"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3175506">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15719538" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3175502</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
