DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ seo-2008-1 in vitro In vitro elisa enzyme linked immunosorbent assay ELISA ELISA elisa predetermined predetermined participant predetermined Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. DIP original experiment: DIP-111178X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. Only protein-protein interactions imex curation seo-2008-2 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. DIP original experiment: DIP-111181X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. Only protein-protein interactions imex curation seo-2008-3 in vitro In vitro elisa enzyme linked immunosorbent assay ELISA ELISA elisa predetermined predetermined participant predetermined Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. DIP original experiment: DIP-111179X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. Only protein-protein interactions imex curation seo-2008-4 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. DIP original experiment: DIP-111182X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. Only protein-protein interactions imex curation seo-2008-5 in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. DIP original experiment: DIP-111180X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Seo NS., Zeng CQ., Hyser JM., Utama B., Crawford SE., Kim KJ., Höök M., Estes MK. Only protein-protein interactions imex curation ita2_human Integrin alpha-2 Platelet membrane glycoprotein Ia Collagen receptor VLA-2 subunit alpha CD49 antigen-like family member B ITGA2 CD49B protein protein human Homo sapiens Human MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKKGILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTELSS nsp4_rots1 Non-structural glycoprotein 4 NCVP5 NS28 protein protein rots1 Rotavirus A (strain SA11-Both G3-P5B[2]-I2-R2-C5-M5-A5-N2-T5-E2-H5) (RV-A) Simian Agent 11 (strain Both) RV-A MEKLTDLNYTLSVITLMNNTLHTILEDPGMAYFPYIASVLTGLFALNKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIYDKLTVQTTGEIDMTKEINQKNVRTLEEWESGKNPYEPREVTAAM ita1_human Integrin alpha-1 ITGA1 Laminin and collagen receptor VLA-1 CD49 antigen-like family member A protein protein human Homo sapiens Human MAPRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK itga2-nsp4_rots1-1 3173641 N/A 3173646 unspecified role unspecified role bait bait ecolx Escherichia coli N/A 3173647 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association false false false itga1-nsp4_rots1-1 3173642 N/A 3173648 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3173647 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association false false false itga1-nsp4_rots1-2 3173643 N/A 3173648 unspecified role unspecified role bait bait ecolx Escherichia coli N/A 3173647 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association false false false itga2-nsp4_rots1-2 3173644 N/A 3173646 unspecified role unspecified role bait bait His tag His tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3173647 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association false false false itga2-nsp4_rots1-3 3173645 N/A 3173646 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3173647 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association false false false