DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ zeng-2008-1 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68427X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-2 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68420X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-3 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68429X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-4 in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68423X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-5 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68425X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-6 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68421X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-7 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68428X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-8 in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68431X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-9 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68430X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-10 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68426X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-11 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68422X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation zeng-2008-12 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. DIP original experiment: DIP-68424X Structure (London, England : 1993) 2008 IMEx Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Zeng L., Zhang Q., Gerona-Navarro G., Moshkina N., Zhou MM. Only protein-protein interactions imex curation nh3k9ac H3-K9ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) RTKQTARKSTGGKAP kat2b_human Histone acetyltransferase KAT2B P300/CBP-associated factor PCAF Lysine acetyltransferase 2B Histone acetyltransferase PCAF KAT2B Spermidine acetyltransferase KAT2B protein protein human Homo sapiens Human MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK h4k20ac H4-K20ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) GGAKRHRKVLRDNIQ cbp_human CREB-binding protein CREBBP CBP Histone lysine acetyltransferase CREBBP Protein-lysine acetyltransferase CREBBP protein protein human Homo sapiens Human MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL h4k16ac H4-K16ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) GLGKGGAKRHRKVLR p53k382ac p53-K382ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) QSTSRHKKLMFKTEG nh3k36ac H3-K36ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) APATGGVKKPHRYRP h3k14ac H3-K14ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) ARKSTGGKAPRKQLA tatk50acfl Tat-K50ac-Fl peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) GGGGSYGRKKRRQRC tatk50ac Tat-K50ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) LGISYGRKKRRQRRA h3k9-1 H3K9 peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) ARTKQTARKSTGGKA h3k36ac H3-K36ac peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) ATGGVKKPHRYK kat2b-nh3k9ac-1 3170486 N/A 3170498 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false crebbp-h4k20ac-1 3170487 N/A 3170500 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170501 unspecified role unspecified role unspecified role unspecified role Region 1082-1197 Region 1082-1197 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false h4k16ac-kat2b-1 3170488 N/A 3170502 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false crebbp-p53k382ac-1 3170489 N/A 3170503 unspecified role unspecified role unspecified role unspecified role Region 5-12 Region 5-12 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3170501 unspecified role unspecified role unspecified role unspecified role Region 1082-1197 Region 1082-1197 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false kat2b-nh3k36ac-1 3170490 N/A 3170504 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false crebbp-nh3k36ac-1 3170491 N/A 3170504 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170501 unspecified role unspecified role unspecified role unspecified role Region 1082-1197 Region 1082-1197 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false h3k14ac-kat2b-1 3170492 N/A 3170505 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false kat2b-tatk50acfl-1 3170493 N/A 3170506 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false kat2b-tatk50ac-1 3170494 N/A 3170507 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false h3k9ac-kat2b-1 3170495 N/A 3170508 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false crebbp-p53k382ac-2 3170496 N/A 3170503 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170501 unspecified role unspecified role unspecified role unspecified role Region 1082-1197 Region 1082-1197 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false h3k36ac-kat2b-1 3170497 N/A 3170509 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3170499 unspecified role unspecified role unspecified role unspecified role Region 719-832 Region 719-832 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false