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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
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            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3169948">
                <names>
                    <shortLabel>zhou-2008-8</shortLabel>
                </names>
                <bibref>
                    <xref>
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                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-68596X" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9205" refType="imex-primary" refTypeAc="MI:0662"/>
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                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse</shortLabel>
                            <fullName>Mus musculus</fullName>
                            <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>pull down</shortLabel>
                        <fullName>pull down</fullName>
                    </names>
                    <xref>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Zhou X., Ferraris JD., Dmitrieva NI., Liu Y., Burg MB.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-68596X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Zhou X.,  Ferraris JD.,  Dmitrieva NI.,  Liu Y.,  Burg MB.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3169949">
                <names>
                    <shortLabel>mk14_rat</shortLabel>
                    <fullName>Mitogen-activated protein kinase 14</fullName>
                    <alias typeAc="MI:0301" type="gene name">Mapk14</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Csbp1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Csbp2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Mitogen-activated protein kinase p38 alpha</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CRK1</alias>
                </names>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
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                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MSQERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAEPYDQSFESRDFLIDEWKSLTYDEVISFVPPPLDQEEMES</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="function" nameAc="MI:0613">Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO during hypoxic stress</attribute>
                </attributeList>
            </interactor>
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                <names>
                    <shortLabel>dus1_mouse</shortLabel>
                    <fullName>Dual specificity protein phosphatase 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Dusp1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">3ch134</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Mkp1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ptpn10</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ptpn16</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Mitogen-activated protein kinase phosphatase 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein-tyrosine phosphatase 3CH134</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein-tyrosine phosphatase ERP</alias>
                </names>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020422" version="SP_184"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5675221" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032355" secondary="response to estradiol" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029021" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009416" secondary="response to light stimulus" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106306" secondary="protein serine phosphatase activity" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000340" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003595" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032526" secondary="response to retinoic acid" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000387" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070262" secondary="peptidyl-serine dephosphorylation" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051447" secondary="negative regulation of meiotic cell cycle" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006470" secondary="protein dephosphorylation" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035335" secondary="peptidyl-tyrosine dephosphorylation" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007049" secondary="cell cycle" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106307" secondary="protein threonine phosphatase activity" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008343" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001706" secondary="endoderm formation" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090027" secondary="negative regulation of monocyte chemotaxis" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004722" secondary="protein serine/threonine phosphatase activity" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020420" version="SP_184"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016130" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043409" secondary="negative regulation of MAPK cascade" version="SP_184"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903753" secondary="negative regulation of p38MAPK cascade" version="SP_184"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000025025" version="SP_184" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019838" secondary="growth factor binding" version="SP_184"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-9205-1" id="3169951">
                <names>
                    <shortLabel>mapk14-dusp1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-59375E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9205-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15695062" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3169948</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3169952">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15695067" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3169949</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3169953">
                                <names>
                                    <shortLabel>GST-tag</shortLabel>
                                    <fullName>GST-tag</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15695068" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>tag</shortLabel>
                                        <fullName>tag</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3169954">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15695066" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3169950</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
