DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ gonzlez_maeso-2008-1 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. DIP original experiment: DIP-250277X Nature 2008 IMEx Identification of a serotonin/glutamate receptor complex implicated in psychosis. González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. Only protein-protein interactions imex curation gonzlez_maeso-2008-2 human Homo sapiens Human fret fluorescent resonance energy transfer FRET RET FRET analysis FRET RET FRET analysis fret predetermined predetermined participant predetermined González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. DIP original experiment: DIP-250280X Nature 2008 IMEx Identification of a serotonin/glutamate receptor complex implicated in psychosis. González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. Only protein-protein interactions imex curation gonzlez_maeso-2008-3 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. DIP original experiment: DIP-250278X Nature 2008 IMEx Identification of a serotonin/glutamate receptor complex implicated in psychosis. González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. Only protein-protein interactions imex curation gonzlez_maeso-2008-4 human Homo sapiens Human bret bioluminescence resonance energy transfer BRET LRET LRET BRET bret predetermined predetermined participant predetermined González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. DIP original experiment: DIP-250279X Nature 2008 IMEx Identification of a serotonin/glutamate receptor complex implicated in psychosis. González-Maeso J., Ang RL., Yuen T., Chan P., Weisstaub NV., López-Giménez JF., Zhou M., Okawa Y., Callado LF., Callado LF., Milligan G., Gingrich JA., Filizola M., Meana JJ., Sealfon SC. Only protein-protein interactions imex curation p28223-1 5-hydroxytryptamine receptor 2A HTR2A HTR2 Serotonin receptor 2A protein protein human Homo sapiens Human MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV grm2_human Metabotropic glutamate receptor 2 GRM2 GPRC1B MGLUR2 protein protein human Homo sapiens Human MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL htr2a-grm2-1 3168433 N/A 3168437 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3168438 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false htr2a-grm2-2 3168434 N/A 3168438 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept eYFP-tag eYFP-tag yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human N/A 3168437 unspecified role unspecified role fluorescence donor fluorescence donor eCFP-tag eCFP-tag cfp tag cyan fluorescent protein tag CFP cyan fluorescent protein cyan fluorescent protein CFP cfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human direct interaction direct interaction false false false htr2a-grm2-3 3168435 N/A 3168437 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3168438 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false grm2-htr2a-5 3168436 N/A 3168438 unspecified role unspecified role fluorescence donor fluorescence donor Rluc-tag Rluc-tag renilla luciferase renilla luciferase protein tag renilla luciferase c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human N/A 3168437 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human direct interaction direct interaction false false false