DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ wu-2008-20 human Homo sapiens Human comigration in sds comigration in sds page comigration in sds western blot western blot Immuno blot Immuno blot Wu CJ., Ashwell JD. DIP original experiment: DIP-68328X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation wu-2008-21 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wu CJ., Ashwell JD. DIP original experiment: DIP-68323X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation wu-2008-22 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wu CJ., Ashwell JD. DIP original experiment: DIP-68326X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation wu-2008-23 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Wu CJ., Ashwell JD. DIP original experiment: DIP-68324X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation wu-2008-24 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wu CJ., Ashwell JD. DIP original experiment: DIP-68327X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation wu-2008-25 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wu CJ., Ashwell JD. DIP original experiment: DIP-68329X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation wu-2008-26 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Wu CJ., Ashwell JD. DIP original experiment: DIP-68325X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Wu CJ., Ashwell JD. Only protein-protein interactions imex curation ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG bcl10_human B-cell lymphoma/leukemia 10 BCL10 CIPER CLAP Cellular homolog of vCARMEN Mammalian CARD-containing adapter molecule E10 Cellular-E10 CARD-like apoptotic protein B-cell CLL/lymphoma 10 CED-3/ICH-1 prodomain homologous E10-like regulator CARD-containing molecule enhancing NF-kappa-B protein protein human Homo sapiens Human MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVGRTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ nemo_human NF-kappa-B essential modulator IKBKG FIP3 NEMO NF-kappa-B essential modifier Inhibitor of nuclear factor kappa-B kinase subunit gamma IkB kinase-associated protein 1 FIP-3 protein protein human Homo sapiens Human MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE bcl10-ub-2 3168025 N/A 3168032 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human N/A 3168033 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human covalent binding covalent binding false false false bcl10-ub-3 3168026 N/A 3168032 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3168033 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false ikbkg-bcl10-4 3168027 N/A 3168034 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3168033 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false bcl10-ub-4 3168028 N/A 3168032 unspecified role unspecified role prey prey Ha tag Ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false human Homo sapiens Human N/A 3168033 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false ikbkg-bcl10-5 3168029 N/A 3168034 unspecified role unspecified role bait bait Q9Y6K9:p.Leu329Pro L329P mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain false Ha tag Ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3168033 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false bcl10-ub-5 3168030 N/A 3168032 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3168033 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false O95999:p.[Lys31Arg;Lys63Arg] K31R,K63R mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human physical association physical association false false false ikbkg-bcl10-6 3168031 N/A 3168033 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3168034 unspecified role unspecified role bait bait GST tag GST tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli physical association physical association false false false