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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3167518">
                <names>
                    <shortLabel>bellinger-2008-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18268335" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-68285X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9083" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0711074105" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15684721" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse</shortLabel>
                            <fullName>Mus musculus</fullName>
                            <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Bellinger AM., Reiken S., Dura M., Murphy PW., Deng SX., Landry DW., Nieman D., Lehnart SE., Samaru M., LaCampagne A., Marks AR.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-68285X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Bellinger AM.,  Reiken S.,  Dura M.,  Murphy PW.,  Deng SX.,  Landry DW.,  Nieman D.,  Lehnart SE.,  Samaru M.,  LaCampagne A.,  Marks AR.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3167519">
                <names>
                    <shortLabel>bellinger-2008-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18268335" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-68286X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15684739" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9083" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0711074105" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Bellinger AM., Reiken S., Dura M., Murphy PW., Deng SX., Landry DW., Nieman D., Lehnart SE., Samaru M., LaCampagne A., Marks AR.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-68286X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Bellinger AM.,  Reiken S.,  Dura M.,  Murphy PW.,  Deng SX.,  Landry DW.,  Nieman D.,  Lehnart SE.,  Samaru M.,  LaCampagne A.,  Marks AR.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3167520">
                <names>
                    <shortLabel>pde4d_mouse</shortLabel>
                    <fullName>cAMP-specific 3',5'-cyclic phosphodiesterase 4D</fullName>
                    <alias typeAc="MI:0301" type="gene name">Pde4d</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DPDE3</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q01063" version="SP_62" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000177907" version="SP_179" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004115" secondary="3',5'-cyclic-AMP phosphodiesterase activity" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000136485" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" secondary="aging" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_179"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2KF58" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-418555" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006198" secondary="cAMP catabolic process" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035264" secondary="multicellular organism growth" version="SP_179"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8C4Q7" version="SP_62" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002027" secondary="regulation of heart rate" version="SP_179"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q01063" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901898" secondary="negative regulation of relaxation of cardiac muscle" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051117" secondary="ATPase binding" version="SP_179"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6TRH9" version="SP_62" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030593" secondary="neutrophil chemotaxis" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_035186.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004114" secondary="3',5'-cyclic-nucleotide phosphodiesterase activity" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050900" secondary="leukocyte migration" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" version="SP_179"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-180024" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002073" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061028" secondary="establishment of endothelial barrier" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901844" secondary="regulation of cell communication by electrical coupling involved in cardiac conduction" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040844" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036971" version="SP_179"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8CG05" version="SP_62" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034705" secondary="potassium channel complex" version="SP_179"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7764239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071320" secondary="cellular response to cAMP" version="SP_179"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29706N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033137" secondary="negative regulation of peptidyl-serine phosphorylation" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003607" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023088" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_179"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006517710.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005891" secondary="voltage-gated calcium channel complex" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704" secondary="calcium channel complex" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045822" secondary="negative regulation of heart contraction" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000113488" version="SP_179" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0086004" secondary="regulation of cardiac muscle cell contraction" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000021699" version="SP_179" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006939" secondary="smooth muscle contraction" version="SP_179"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="UNK-5385073" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010880" secondary="regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_179"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071872" secondary="cellular response to epinephrine stimulus" version="SP_179"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023174" version="SP_179"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000122041" version="SP_179" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043951" secondary="negative regulation of cAMP-mediated signaling" version="SP_179"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MERDTCDVLSRSKSASEETLHSCNEEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQADLRSESENIPRPTSLPLKILPLIAVTSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="function" nameAc="MI:0613">Regulates the levels of cAMP in the cell</attribute>
                </attributeList>
            </interactor>
            <interactor id="3167521">
                <names>
                    <shortLabel>fkb1a_mouse</shortLabel>
                    <fullName>Peptidyl-prolyl cis-trans isomerase FKBP1A</fullName>
                    <alias typeAc="MI:0301" type="gene name">Fkbp1a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fkbp1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">12 kDa FK506-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Calstabin-1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FK506-binding protein 1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Immunophilin FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rotamase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P26883" version="SP_105" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046332" secondary="SMAD binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032092" secondary="positive regulation of protein binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_032045.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032925" secondary="regulation of activin receptor signaling pathway" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098562" secondary="cytoplasmic side of membrane" version="SP_172"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000032966" version="SP_172" refType="gene"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q545E9" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005160" secondary="transforming growth factor beta receptor binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902991" secondary="regulation of amyloid precursor protein catabolic process" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031398" secondary="positive regulation of protein ubiquitination" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019221" secondary="cytokine-mediated signaling pathway" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061077" secondary="chaperone-mediated protein folding" version="SP_172"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000037206" version="SP_172" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000044011" version="SP_172" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031312" secondary="extrinsic component of organelle membrane" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060347" secondary="heart trabecula formation" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005528" secondary="FK506 binding" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001289007.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097435" secondary="supramolecular fiber organization" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2173789" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2025928" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003007" secondary="heart morphogenesis" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042098" secondary="T cell proliferation" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001179" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030544" secondary="Hsp70 protein binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032515" secondary="negative regulation of phosphoprotein phosphatase activity" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003755" secondary="peptidyl-prolyl cis-trans isomerase activity" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001289008.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031000" secondary="response to caffeine" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990000" secondary="amyloid fibril formation" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-166208" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007183" secondary="SMAD protein complex assembly" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048185" secondary="activin binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055010" secondary="ventricular cardiac muscle tissue morphogenesis" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032880" secondary="regulation of protein localization" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030512" secondary="negative regulation of transforming growth factor beta receptor signaling pathway" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_172"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29707N"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P26883" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000413" secondary="protein peptidyl-prolyl isomerization" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001289006.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034713" secondary="type I transforming growth factor beta receptor binding" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043679" secondary="axon terminus" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_172"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6379901" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050776" secondary="regulation of immune response" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001289009.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQMSVGQRAKLIISSDYAYGATGHPGIIPPHATLVFDVELLKLE</sequence>
            </interactor>
            <interactor id="3167522">
                <names>
                    <shortLabel>ryr1_mouse</shortLabel>
                    <fullName>Ryanodine receptor 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ryr1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle calcium release channel</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle-type ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Type 1 ryanodine receptor</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="E9PZQ0" version="SP_8" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" secondary="outflow tract morphogenesis" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031000" secondary="response to caffeine" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009460" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" secondary="calmodulin binding" version="SP_89"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q60834" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014821" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005790" secondary="smooth endoplasmic reticulum" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014808" secondary="release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003877" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006816" secondary="calcium ion transport" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048741" secondary="skeletal muscle fiber development" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" secondary="protease binding" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016093" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_89"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q61779" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000699" version="SP_89"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_033135.2"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013333" version="SP_89"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q80UQ5" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q80X16" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q99JF9" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014802" secondary="terminal cisterna" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042383" secondary="sarcolemma" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" secondary="protein homotetramerization" version="SP_89"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5578775" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013662" version="SP_89"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2672351" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043931" secondary="ossification involved in bone maturation" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704" secondary="calcium channel complex" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071277" secondary="cellular response to calcium ion" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031234" secondary="extrinsic component of cytoplasmic side of plasma membrane" version="SP_89"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-642079" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035762" version="SP_89"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29705N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992" version="SP_89"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000179893" version="SP_89" refType="transcript"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q62235" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030315" secondary="T-tubule" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051480" secondary="regulation of cytosolic calcium ion concentration" version="SP_89"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000030592" version="SP_89" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030659" secondary="cytoplasmic vesicle membrane" version="SP_89"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q62173" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q78EJ6" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035761" version="SP_89"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000137123" version="SP_89" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071313" secondary="cellular response to caffeine" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003032" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031674" secondary="I band" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048763" secondary="calcium-induced calcium release activity" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035764" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219" secondary="ryanodine-sensitive calcium-release channel activity" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006937" secondary="regulation of muscle contraction" version="SP_89"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q61780" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q7TNG1" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070296" secondary="sarcoplasmic reticulum calcium ion transport" version="SP_89"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q62196" version="SP_8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030314" secondary="junctional membrane complex" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043136" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071318" secondary="cellular response to ATP" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001870" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036300" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005245" secondary="voltage-gated calcium channel activity" version="SP_89"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035910" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031301" secondary="integral component of organelle membrane" version="SP_89"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" secondary="calcium channel activity" version="SP_89"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MGDGGGEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSGCEEGFVTGGHVLRLFHGHMDECLTISPSDSDDQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLGLTEDQGLVVVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDSFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRTNCALFSTNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRREGPRGPHLVGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVDSQSRGDRARIFRAEKSYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADDLAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLEHPHYEVARMDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLASPGLQPPAEDEARAAEPDTDYENLRRSAGGWGEAEGGKDGTAKEGTPGGTAQAGVEAQPARAENEKDATTEKNKKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPADNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVVQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVDTRRAGERLGWAVQCQEPLMMMALHIPEENRCMDILELSERLDLQRFHSHTLSLYRSVCALGNNRVAHALCSHVDQAQLLHALEDARLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGATEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVKQILKMIEPEVFREEEEVEEEGEEEEEDEEEKEEDEEEEAHEKEDEEKEEAEDAAEEEKEELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAECYVDKMQGNQRGRYGLLMKAFTMSAAETARRTREFRSPPQEQINMLLHFKNGADEEECPLPEEIRQELVNFHQDLLAHCGIQLEGEEEEPEEESTLGSRLMSLLEKVKLVKKTEEKPEEEPAPEEHKPQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISVSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPETHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCLCAIAGALPPDYVDASYSSKTEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGEEEKTEKKKTRKISQTAQTYDPREGYNPQPPDLSVVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTRNPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMAEIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNPNAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMAKAGDVQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGVPGREEDADDPEKIVRRVQEVSAVLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEEGGEEEEVEVSFEEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMEMFVSFCEDTIFEMQIAAQISEPEGEPEEDEDEGAEEAEEGAAGSDGSGSAAAAGVWVWLAATAGRTLRGLSYRSLRRRVRRLRRLTAREAATAVAALLWALVTRAGGAGAGAAAGALRLLWGSLFGGGLVDSAKKVTVTELLAGMPDPTGDEVHGQQPSGAGSDAEGEGEGEGEGDAADGAGDEEAAADQAGTGGADGAVAVADGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEEPPPEPEPEPEPEPEKADTENGEKEVPEPPPEPPKKTPPPPPPKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDIEGSGAGDMSGAGSGDGSGWGSRAGEEVEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNERKPDPPPGLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS</sequence>
                <attributeList>
                    <attribute name="caution" nameAc="MI:0618">This sequence has been withdrawn from Uniprot.</attribute>
                    <attribute name="crc64">D15D2E764B445573</attribute>
                </attributeList>
            </interactor>
            <interactor id="3167523">
                <names>
                    <shortLabel>q08499-2</shortLabel>
                    <fullName>cAMP-specific 3',5'-cyclic phosphodiesterase 4D</fullName>
                    <alias typeAc="MI:0301" type="gene name">PDE4D</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DPDE3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PDE43</alias>
                    <alias typeAc="MI:0304" type="isoform synonym">hPDE4D3</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q08499-2" version="SP_86" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-92306" refType="intact-secondary"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1642831" refType="isoform-parent" refTypeAc="MI:0243"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8095525" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000360047" version="SP_223" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000353152" version="SP_223" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000113448" version="SP_223" refType="gene"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT</sequence>
                <attributeList>
                    <attribute name="isoform-comment" nameAc="MI:0637">Contains a phosphoserine at position 54. Activated by phosphorylation at Ser-53. Mutagenesis of Ser-54 abolishes activation. </attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="3167524">
                <names>
                    <shortLabel>fkb1a_human</shortLabel>
                    <fullName>Peptidyl-prolyl cis-trans isomerase FKBP1A</fullName>
                    <alias typeAc="MI:0301" type="gene name">FKBP1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FK506-binding protein 1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rotamase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Immunophilin FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">12 kDa FK506-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Calstabin-1</alias>
                </names>
                <xref>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKH" version="SP_182"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FKE" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKT" version="SP_182"/>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE</sequence>
            </interactor>
            <interactor id="3167525">
                <names>
                    <shortLabel>ryr1_human</shortLabel>
                    <fullName>Ryanodine receptor 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">RYR1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RYDR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle-type ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle calcium release channel</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Type 1 ryanodine receptor</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014808" secondary="release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" secondary="calmodulin binding" version="SP_234"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000196218" version="SP_234" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030659" secondary="cytoplasmic vesicle membrane" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042383" secondary="sarcolemma" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005790" secondary="smooth endoplasmic reticulum" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" secondary="protein homotetramerization" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071277" secondary="cellular response to calcium ion" version="SP_234"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001036188.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219" secondary="ryanodine-sensitive calcium-release channel activity" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048763" secondary="calcium-induced calcium release activity" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014701" secondary="junctional sarcoplasmic reticulum membrane" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_234"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5578775" version="SP_234"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000352608" version="SP_234" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035764" version="SP_234"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UHI" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003877" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015278" secondary="calcium-release channel activity" version="SP_234"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NPK1" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013333" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320" version="SP_234"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UHS" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051480" secondary="regulation of cytosolic calcium ion concentration" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031674" secondary="I band" version="SP_234"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071313" secondary="cellular response to caffeine" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035761" version="SP_234"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000359596" version="SP_234" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005245" secondary="voltage-gated calcium channel activity" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821" version="SP_234"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16368" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035762" version="SP_234"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014821" version="SP_234"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGDAEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDIILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSRCEEGFVTGGHVLRLFHGHMDECLTISPADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRVRHVTTGQYLALTEDQGLVVVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIHSTNGLYNQFIKSLDSFSGKPRGSGPPAGTALPIEGVILSLQDLIIYFEPPSEDLQHEEKQSKLRSLRNRQSLFQEEGMLSMVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRSNCALFSTNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSKWYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVISCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVGQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRCDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKGLPQFEPVPLEHPHYEVSRVDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGGWSEAENGKEGTAKEGAPGGTPQAGGEAQPARAENEKDATTEKNKKRGFLFKAKKVAMMTQPPATPTLPRLPHDVVPADNRDDPEIILNTTTYYYSVRVFAGQEPSCVWAGWVTPDYHQHDMSFDLSKVRVVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFQSERKNPAPQCPPRLEMQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSTENGHPRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGAAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYGLLIKAFSMTAAETARRTREFRSPPQEQINMLLQFKDGTDEEDCPLPEEIRQDLLDFHQDLLAHCGIQLDGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSLQELVSHMVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLVAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGIRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLEDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMSLCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDPELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEEKTEKKKTRKISQSAQTYDPREGYNPQPPDLSAVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELDSSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPSALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLQSHFIPTIGRLRKRAGKVVSEEEQLRLEAKAEAQEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAQWLTEPNPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMAKAGDIQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLITLAKTRYALKDTDEEVREFLHNNLHLQGKVEGSPSLRWQMALYRGVPGREEDADDPEKIVRRVQEVSAVLYYLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEAEEEVEVSFEEKQMEKQRLLYQQARLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFSGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLHNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPEGEPETDEDEGAGAAEAGAEGAEEGAAGLEGTAATAAAGATARVVAAAGRALRGLSYRSLRRRVRRLRRLTAREAATAVAALLWAAVTRAGAAGAGAAAGALGLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGEGASEGAGDAAEGAGDEEEAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVDGVEEELPPEPEPEPEPELEPEKADAENGEKEEVPEPTPEPPKKQAPPSPPPKKEEAGGEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDVSGAGSGGSSGWGLGAGEEAEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAELLGMDLATLEITAHNERKPNPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-9083-2" id="3167526">
                <names>
                    <shortLabel>mryr1-fkbp1a-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-59183E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9083-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15684732" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3167518</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3167527">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15684737" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3167520</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3167528">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15684738" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3167521</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3167529">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15684736" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3167522</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-9083-1" id="3167530">
                <names>
                    <shortLabel>ryr1-fkbp1a-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-59184E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9083-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15684750" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3167519</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3167531">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15684755" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3167523</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3167532">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15684756" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3167524</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3167533">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15684754" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3167525</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
