DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ callejo-2008-1 drome Drosophila melanogaster (Fruit fly) Fruit fly anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Callejo A., Culi J., Guerrero I. DIP original experiment: DIP-68219X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Patched, the receptor of Hedgehog, is a lipoprotein receptor. Callejo A., Culi J., Guerrero I. Only protein-protein interactions imex curation aplp_drome Apolipophorins apolpp Retinoid- and fatty acid-binding glycoprotein RfaBp Rfabg CG11064 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MARMKYNIALIGILASVLLTIAVNAENACNLGCPKSDNGLLKYIPGNYYDYSFDSILTIGASSDVPNDSDDTSLKVSGSAKIFAKGNCGYTLQLSSVKVTNTKESVEKKILNSIQKPVQFTLVSGILEPQICSDSSDLDYSLNIKRAVVSLLQSGIEAEHEVDVFGMCPTHTSTSKVGNANIITKARNLNSCSHREQINSGLVSGKVNEKAGITSSLLLQANYIKESRIVNHLIENVQLTETYKFIGNTKRNSDISAKVVTILKLKNPSGTKANSPGTGSTVRSLIFQRPETYTSKNINALKTILSDLVDSTGDYVKKETAKKFVEFIRLLRQSDSETLLELAAFPHPNKVLARKVYLDGLFRTSTAESARVILKQLSKFDEKEKLLAILSLNIVKSVDKETLNQAASQLLPNAPKELYIAVGNLVAKYCLKNYCQGPEIDAISKKFSDGLKHCKPNTKREEERIVYILKGLGNAKSLSGNTVAALSECASTGRSNRIRVAALHAFSKVKCEETLQSKSLELLKNRNEDSELRIEAYLSAISCPNAEVANQISEIVNSETVNQVGGFISSNLKAIRDSTDVSRDQQKYHLANIRVTKTFPVDYRRYSFNNEVSYKLESLGVGASTDYQIIYSQHGFLPRSSRINVTTEFFGTNYNVFEASVRQENVEDVLEYYLGPKGLVNKDFDEIVKLIEVGNNGVAAGGRARRSIVDDVSKISKKYKMYGVKNVQDLNLDVSLKLFGSELAFLSLGDNIPSSLDDIINYFSTSFEKAKQELSSFEKQFSSHHLFLDTDLAYPTSIGVPLELVAQGFAATKVDLAVSLDINAILEQNWQKAKYRLKFVPSVDINANVQIGFNAQVLSTGLRVVSSAHSATGSDITVAVISDGEGFNVDLELPREKLELINFNVDTELYVAEQDKQKAIALKGNKKNKNSQPSEICFNQLELVGLNICIKSSTSLSEVQAGNGNVAERGLSVSEKFHLSRPFNFAVYLTTERKFTFKGIHTQEAFSQKWKLDYSTPGSKVSHDTTVVYELGNKPKTFSRLSFDNSQCHFAVEGGINNDKNELVVYGQYEQDKEIKKSKIGFSKNGNEYKPLIEIQDNNGISNSINGYHADGKIVVKKNSNNIERYNFENFQVSNSNNAHVAVNGWSDVGTNSLTSELRISLDHQTFLIKENLKLENGLYEAGFFINDEHSPENIYGSSIHLTIADQSYALKTNGKAAAWSIGSDGSFNFQKLADSNSARAGSLVENVEIQYKNKQVGGIKIMSNFDVNKMDVDVEISREQKIGSIIVKYESNQRHAQDYSLEASAKINKHSIDVISKCDFNGNVYVVDNSLVTSWGTLLSAKGEIGQRYSAQDININIQGNVQISGKDKVTQWILKVIGTPDKTNSDFRISRDTSELIKLTSESQHPQDKISFAKLNLIVKNQLTAKGEFRVAKNGKGDFTASIDTLKTEPKHKLEIESKFHIQSPKYDIDASLTLDGKRKVHLKSENTIEKLKFSTKNIGEANDKIIAFEANGSLKGELRGNGEIQGTFIFNAPDGRVIDGSINRKISTNAKSGLSQGNIDAQLSDTPFGSNKKRSISLIGKLDRLNTKTKEFSANSNLVYTAFNGEKSEISYQIKQQPNGDAKNIDFSLKAYGNPLPQPFEIAFALGDYSAQHAVVSITSKYGEIFSVSANGNYNNNQALEYGLQANIEIPKSTLKSLEINSHGKVLKSLIGNENAAYNVEFFLDSKTSLGQYARVNTVWNGTANDGSYDFEAQTNNMESPLKFNGKYHRKQTGNIKDGDLTGKQTYVLNAQYGAQYVKMDASLGYGAEKVDIAYVIDSSFDSVKDIKVNIRTFKPLDDSTYVVTALFKQTDKSYGLDTTFYHSAHKKGVDIRLDLLKEKPIIISSIAELLGDRKGKVLFEILNLADLDIKINSEASYVSIDEFYIIVNWSSKKLKLDGYELEARAQSKNIKIQLKNENGIIFSGTATYALKKELNKTIIDGQGKVQYQGKALSGNFKLTRQHFDFGTDREVGFSYTFMGNLGSKNGLGTLKITNKEFNTKFSVCEEKRQCTNLIVQSIVSIDEQKLDAVEHTTLIIVDLRDFGYPYEFELKSQNTRQGLKYQYHLDSFIITGNNFKYQFTANVQPTSSTIKLALPKRQILFETTQKIPADGSLFGRYEQTASFFIDKLQKPDDVARFSAIVDVTGTERVAFNANGKLKFEHPTIRPLSISGQLNGDVNQQIASAEVIFDIFRLPEQKVVGNSELRNSRSQNGFNIAYITTVKSAGLQFQYQINSNAAVDIEAHEYNIGLELNNGEIDVKAISFLNKEKFEISLSESNKHIIYIVGDFSKQNHYAKLNTKVQILDKNPIEITSEVQPNSAKIILKRQDFIDGTAEVKLGKEFKVDVIGSGKQLFNGRVALDATNFLQTNYFINEDHLNGFWHIVESEINKDSEYISENIKERLKKSRQVTDKIVKLAKEAGPDFSKLQGKLLDYKNDIVQELEADQSIAPIIDGIRTLFKKIAGIVDDINKAISEILEKAQKSIVDIYDKLQALWKDSLLKAWEDFIITVQKLISTLKTEFIKICTQSFKDLLSALEKYGPALKNYGKAIGEIVKPINDAAQEVIKIVVNAAEGVTHEFKQYVASLPSFESIRNEFNDKVKVLKLFEKATELTNSLFDQINILPQTPETSEFLQKLHDYLIAKLKQEHIDNEKYIEELGQLLIKAVRSIWVSIRSTYPGSSDHVIDFQSWIGSLTHSFDSLAVLPSILSFRSSILNCLLNENWDVVFNKKLLYSWIFFNDFELRGHVVDGKHIFTFDGLNFAYPGNCKYILAQDSVDNNFTIIGQLTNGKLKSITLIDREGSYFEVADNLALKLNGNLVEYPQHLSGLHAWRRFYTIHLYSEYGVGIVCTSDLKVCHININGFYTSKTRGLLGNGNAEPYDDFLLIDGTLAENSAALGNDYGVGKCTAIEFDNNQFKSSKRQEMCSELFGIESTLAFNFITLDSRPYRKACDIALAKVAEKEKEATACTFALAYGSAVKQINKWVLLPPRCIKCAGPAGQHDFGDEFTVKLPNNKVDVVFVVDINVTPGVLSNLIAPAINDIRESLRSRGFSDVQVGVIVFEETKRYPALLTSDGGKINYKGNVADVKLAGIKSFCDNCVEQIITEKRILDIYNSLKEIVKGIAPQADEKAFQLALDYPFRAGAAKSIIGVRSDSLEYKNWWKFVRAQLTGSITKFDGALIHLIAPVKGLSLEGVLSEKLIGFNSRLVATVDGKDSKKRTKLQFDNDMGIDFVLNNGGWVFATQNFEKLKASDQKKMLNQITSSLADTLFKTEIVSDCRCLPIHGLHGQHKCVIKSSTFVANKKAKSA ptc_drome Protein patched ptc CG2411 Hedgehog receptor protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MDRDSLPRVPDTHGDVVDEKLFSDLYIRTSWVDAQVALDQIDKGKARGSRTAIYLRSVFQSHLETLGSSVQKHAGKVLFVAILVLSTFCVGLKSAQIHSKVHQLWIQEGGRLEAELAYTQKTIGEDESATHQLLIQTTHDPNASVLHPQALLAHLEVLVKATAVKVHLYDTEWGLRDMCNMPSTPSFEGIYYIEQILRHLIPCSIITPLDCFWEGSQLLGPESAVVIPGLNQRLLWTTLNPASVMQYMKQKMSEEKISFDFETVEQYMKRAAIGSGYMEKPCLNPLNPNCPDTAPNKNSTQPPDVGAILSGGCYGYAAKHMHWPEELIVGGAKRNRSGHLRKAQALQSVVQLMTEKEMYDQWQDNYKVHHLGWTQEKAAEVLNAWQRNFSREVEQLLRKQSRIATNYDIYVFSSAALDDILAKFSHPSALSIVIGVAVTVLYAFCTLLRWRDPVRGQSSVGVAGVLLMCFSTAAGLGLSALLGIVFNAASTQVVPFLALGLGVDHIFMLTAAYAESNRREQTKLILKKVGPSILFSACSTAGSFFAAAFIPVPALKVFCLQAAIVMCSNLAAALLVFPAMISLDLRRRTAGRADIFCCCFPVWKEQPKVAPPVLPLNNNNGRGARHPKSCNNNRVPLPAQNPLLEQRADIPGSSHSLASFSLATFAFQHYTPFLMRSWVKFLTVMGFLAALISSLYASTRLQDGLDIIDLVPKDSNEHKFLDAQTRLFGFYSMYAVTQGNFEYPTQQQLLRDYHDSFVRVPHVIKNDNGGLPDFWLLLFSEWLGNLQKIFDEEYRDGRLTKECWFPNASSDAILAYKLIVQTGHVDNPVDKELVLTNRLVNSDGIINQRAFYNYLSAWATNDVFAYGASQGKLYPEPRQYFHQPNEYDLKIPKSLPLVYAQMPFYLHGLTDTSQIKTLIGHIRDLSVKYEGFGLPNYPSGIPFIFWEQYMTLRSSLAMILACVLLAALVLVSLLLLSVWAAVLVILSVLASLAQIFGAMTLLGIKLSAIPAVILILSVGMMLCFNVLISLGFMTSVGNRQRRVQLSMQMSLGPLVHGMLTSGVAVFMLSTSPFEFVIRHFCWLLLVVLCVGACNSLLVFPILLSMVGPEAELVPLEHPDRISTPSPLPVRSSKRSGKSYVVQGSRSSRGSCQKSHHHHHKDLNDPSLTTITEEPQSWKSSNSSIQMPNDWTYQPREQRPASYAAPPPAYHKAAAQQHHQHQGPPTTPPPPFPTAYPPELQSIVVQPEVTVETTHSDSNTTKVTATANIKVELAMPGRAVRSYNFTS ptc-rfabg-1 3166355 N/A 3166356 unspecified role unspecified role prey prey Apoli-II 26-706 Apoli-II 26-706 polyprotein frag polyprotein fragment polyprotein frag certain certain sequence position certain certain certain sequence position certain false drome Drosophila melanogaster (Fruit fly) Fruit fly N/A 3166356 unspecified role unspecified role prey prey Apoli-I 707-3351 Apoli-I 707-3351 polyprotein frag polyprotein fragment polyprotein frag certain certain sequence position certain certain certain sequence position certain false drome Drosophila melanogaster (Fruit fly) Fruit fly N/A 3166357 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false drome Drosophila melanogaster (Fruit fly) Fruit fly association association false false false