DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ moody-2007-1 in vitro In vitro protease assay protease assay predetermined predetermined participant predetermined Moody CA., Fradet-Turcotte A., Archambault J., Laimins LA. DIP original experiment: DIP-68784X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification. Moody CA., Fradet-Turcotte A., Archambault J., Laimins LA. Only protein-protein interactions imex curation moody-2007-2 in vitro In vitro protease assay protease assay predetermined predetermined participant predetermined Moody CA., Fradet-Turcotte A., Archambault J., Laimins LA. DIP original experiment: DIP-68785X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification. Moody CA., Fradet-Turcotte A., Archambault J., Laimins LA. Only protein-protein interactions imex curation casp3_human Caspase-3 Apopain Cysteine protease CPP32 Protein Yama SREBP cleavage activity 1 CASP3 CPP32 protein protein human Homo sapiens Human MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH ve1_hpv31 Replication protein E1 E1 ATP-dependent helicase E1 protein protein hpv31 Human papillomavirus type 31 MADPAGTDGEGTGCNGWFYVEAVIDRQTGDNISEDENEDSSDTGEDMVDFIDNCNVYNNQAEAETAQALFHAQEAEEHAEAVQVLKRKYVGSPLSDISSCVDYNISPRLKAICIENNSKTAKRRLFELPDSGYGNTEVETQQMVQVEEQQTTLSCNGSDGTHSERENETPTRNILQVLKTSNGKAAMLGKFKELYGVSFMELIRPFQSNKSTCTDWCVAAFGVTGTVAEGFKTLLQPYCLYCHLQSLACSWGMVMLMLVRFKCAKNRITIEKLLEKLLCISTNCMLIQPPKLRSTAAALYWYRTGMSNISDVYGETPEWIERQTVLQHSFNDTTFDLSQMVQWAYDNDVMDDSEIAYKYAQLADSDSNACAFLKSNSQAKIVKDCGTMCRHYKRAEKRQMSMGQWIKSRCDKVSDEGDWRDIVKFLRYQQIEFVSFLSALKLFLKGVPKKNCILIHGAPNTGKSYFGMSLISFLQGCIISYANSKSHFWLQPLADAKIGMLDDATTPCWHYIDNYLRNALDGNPVSIDVKHKALMQLKCPPLLITSNINAGKDDRWPYLHSRLVVFTFPNPFPFDKNGNPVYELSDKNWKSFFSRTWCRLNLHEEEDKENDGDSFSTFKCVSGQNIRTL casp7_human Caspase-7 ICE-like apoptotic protease 3 Apoptotic protease Mch-3 CMH-1 CASP7 MCH3 protein protein human Homo sapiens Human MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ casp3-e1-1 3164875 N/A 3164877 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli N/A 3164878 enzyme target enzyme target substrate substrate unspecified role unspecified role Region 1-170 Region 1-170 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false casp7-e1-1 3164876 N/A 3164879 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli N/A 3164878 enzyme target enzyme target substrate substrate unspecified role unspecified role Region 1-170 Region 1-170 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false