DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ ramn_maiques-2007-1 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ramón-Maiques S., Kuo AJ., Carney D., Matthews AG., Oettinger MA., Gozani O., Yang W. DIP original experiment: DIP-111307X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Ramón-Maiques S., Kuo AJ., Carney D., Matthews AG., Oettinger MA., Gozani O., Yang W. Only protein-protein interactions imex curation ramn_maiques-2007-2 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ramón-Maiques S., Kuo AJ., Carney D., Matthews AG., Oettinger MA., Gozani O., Yang W. DIP original experiment: DIP-111309X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Ramón-Maiques S., Kuo AJ., Carney D., Matthews AG., Oettinger MA., Gozani O., Yang W. Only protein-protein interactions imex curation ramn_maiques-2007-3 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ramón-Maiques S., Kuo AJ., Carney D., Matthews AG., Oettinger MA., Gozani O., Yang W. DIP original experiment: DIP-111308X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Ramón-Maiques S., Kuo AJ., Carney D., Matthews AG., Oettinger MA., Gozani O., Yang W. Only protein-protein interactions imex curation rag2_mouse V(D)J recombination-activating protein 2 Rag2 Rag-2 protein protein mouse Mus musculus Mouse MSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAIFSKDSCYLPPLRYPATCSYKGSIDSDKHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEPRYGHSIDVVYSRGKSMGVLFGGRSYMPSTQRTTEKWNSVADCLPHVFLIDFEFGCATSYILPELQDGLSFHVSIARNDTVYILGGHSLASNIRPANLYRIRVDLPLGTPAVNCTVLPGGISVSSAILTQTNNDEFVIVGGYQLENQKRMVCSLVSLGDNTIEISEMETPDWTSDIKHSKIWFGSNMGNGTIFLGIPGDNKQAMSEAFYFYTLRCSEEDLSEDQKIVSNSQTSTEDPGDSTPFEDSEEFCFSAEATSFDGDDEFDTYNEDDEDDESVTGYWITCCPTCDVDINTWVPFYSTELNKPAMIYCSHGDGHWVHAQCMDLEERTLIHLSEGSNKYYCNEHVQIARALQTPKRNPPLQKPPMKSLHKKGSGKVLTPAKKSFLRRLFD mint homomint h3 (1) Histone protein protein chemical synthesis Chemical synthesis (Chemical synthesis) ARTQTARKSTGGKAPRKQA h3 (2) Histone 3 protein protein chemical synthesis Chemical synthesis (Chemical synthesis) ARTKQTARKSTGGKAY h3 (1)-rag2-1 3164427 N/A 3164430 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3164431 unspecified role unspecified role unspecified role unspecified role chemical synthesis Chemical synthesis (Chemical synthesis) direct interaction direct interaction false false false h3 (2)-rag2-1 3164428 N/A 3164430 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3164432 unspecified role unspecified role unspecified role unspecified role chemical synthesis Chemical synthesis (Chemical synthesis) direct interaction direct interaction false false false h3 (1)-rag2-2 3164429 N/A 3164430 unspecified role unspecified role prey prey P21784:p.[Tyr415Ala;Met443Ala;Trp453Ala] Y415A, M443A, W453A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false 414_527 binding site 414_527 binding site sufficient to bind sufficient binding region sufficient to bind predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain false GST tag GST tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3164431 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association false false false