DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ wu-2007-10 in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Wu JQ., Hansen DV., Guo Y., Wang MZ., Tang W., Freel CD., Tung JJ., Jackson PK., Kornbluth S. DIP original experiment: DIP-111413X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Wu JQ., Hansen DV., Guo Y., Wang MZ., Tang W., Freel CD., Tung JJ., Jackson PK., Kornbluth S. Only protein-protein interactions imex curation wu-2007-11 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Wu JQ., Hansen DV., Guo Y., Wang MZ., Tang W., Freel CD., Tung JJ., Jackson PK., Kornbluth S. DIP original experiment: DIP-111415X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Wu JQ., Hansen DV., Guo Y., Wang MZ., Tang W., Freel CD., Tung JJ., Jackson PK., Kornbluth S. Only protein-protein interactions imex curation wu-2007-12 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Wu JQ., Hansen DV., Guo Y., Wang MZ., Tang W., Freel CD., Tung JJ., Jackson PK., Kornbluth S. DIP original experiment: DIP-111414X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Wu JQ., Hansen DV., Guo Y., Wang MZ., Tang W., Freel CD., Tung JJ., Jackson PK., Kornbluth S. Only protein-protein interactions imex curation fbx43_xenla F-box only protein 43 fbxo43 emi2 erp1 fbx26 Early mitotic inhibitor 2 Emi1-related protein 1 F-box protein 26 Xerp1 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MANLLENFAAHHSMTAGAKKKADHQDTSVSQDSGYSDSLKGFSPDSHKSGNFLETVTEGYENSENIDPTLILSPIKYELSWGADTRESKQLAPLYETPRVGKKEFSLRRRLLISKATSGGNLDFDVSVCSAESCGREKSLRRIPSHEGSLSNSFADSPRDGSYEPIATSTLKTESESGTSCKKWRLSFAQQRSSTLDDSKSDSIPLPEVENISPVQHSLASSTDDSILYEETIFGAPTTPTCNFIVKEEFQTPISNLAANFRFNLCTPDVGHVSDFDISVTEDSAFHSLSLDKSQDSITDHEGSFQELIQKPRETSKAVNNKSRLRKLDRCRRLSTLRERGSQSEVEEEGNEVPVLSSAYKLKVARASVDEENEFSSDESRVHSLLSSDDLTGKPALRVLHEMLLRSTRKRPQQATVQDLLGSSGCFELPEDSLSRLIGRKMGLETFDILAELKNRNLKHILASILDLVNAASICSMCRVSRDWRDVVLQDKSAHQRRKAYIKKLKTEAEQGRQLSFEDSATRLNILSRSALRSVQIQARSAFRTPTSSLTPGDNKSIHSASKHQEYLKVAKTLFTDEALKPCPRCQYPAKYQALKKRGTCSRKDCGFDFCSLCLCTFHGSKECGTGSAKRIPKKEALPGSAQSKRNLKRL mint ks6a3_human Ribosomal protein S6 kinase alpha-3 Insulin-stimulated protein kinase 1 MAP kinase-activated protein kinase 1b 90 kDa ribosomal protein S6 kinase 3 MAPKAPK1B Ribosomal S6 kinase 2 pp90RSK2 RPS6KA3 ISPK1 RSK2 protein protein human Homo sapiens Human MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPVGRSTLAQRRGIKKITSTAL q6ird3_xenla Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B ppp2r2a.S PP2A ppp2r2a XELAEV_18020223mg protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MAGASGGNDIQWCFSQVKGAVEDDISEADIISTVEFNHSGELLATGDKGGRVVIFQQESKSPYHRGEYSVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEENGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISVNSDYETYLSADDLRVNLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRESALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHNGRYMMTRDYLSVKIWDLNMESRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGPDNVVMTGSYNNFFRMFDRNTKRDITLEASRENSKPRTVLKPRKVCASGKRKKDEITVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDRVN fbxo43-rps6ka3-1 3161431 N/A 3161434 enzyme target enzyme target substrate substrate unspecified role unspecified role Region 1-350 Region 1-350 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3161435 enzyme enzyme unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction false false false fbxo43-ppp2r2a-1 3161432 N/A 3161434 unspecified role unspecified role bait bait Region 1-350 Region 1-350 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3161436 unspecified role unspecified role prey prey xenla Xenopus laevis (African clawed frog) African clawed frog direct interaction direct interaction false false false fbxo43-ppp2r2a-2 3161433 N/A 3161434 unspecified role unspecified role bait bait Region 1-350 Region 1-350 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3161436 unspecified role unspecified role prey prey xenla Xenopus laevis (African clawed frog) African clawed frog direct interaction direct interaction false false false