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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
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            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3158867">
                <names>
                    <shortLabel>ago-2007-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17632548" refType="primary-reference" refTypeAc="MI:0358"/>
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                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-253175X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="2PNO" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21175" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="4896">
                        <names>
                            <shortLabel>schpm</shortLabel>
                            <fullName>Schizosaccharomyces pombe (fission yeast)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ago H., Kanaoka Y., Irikura D., Lam BK., Shimamura T., Austen KF., Miyano M.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253175X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Ago H.,  Kanaoka Y.,  Irikura D.,  Lam BK.,  Shimamura T.,  Austen KF.,  Miyano M.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3158868">
                <names>
                    <shortLabel>ago-2007-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17632548" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-253176X" refType="identity" refTypeAc="MI:0356"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="4896">
                        <names>
                            <shortLabel>schpm</shortLabel>
                            <fullName>Schizosaccharomyces pombe (fission yeast)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>molecular sieving</shortLabel>
                        <fullName>molecular sieving</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Gel Filtration</alias>
                        <alias typeAc="MI:0303" type="go synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Gel Filtration</alias>
                        <alias typeAc="MI:1041" type="synonym">Sizing column</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0071" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ago H., Kanaoka Y., Irikura D., Lam BK., Shimamura T., Austen KF., Miyano M.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253176X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Ago H.,  Kanaoka Y.,  Irikura D.,  Lam BK.,  Shimamura T.,  Austen KF.,  Miyano M.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3158869">
                <names>
                    <shortLabel>ltc4s_human</shortLabel>
                    <fullName>Leukotriene C4 synthase</fullName>
                    <alias typeAc="MI:0301" type="gene name">LTC4S</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Leukotriene-C(4) synthase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Glutathione S-transferase LTC4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Leukotriene-C4 synthase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q16873" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3B29" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JC7" version="SP_186"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018295" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCV" version="SP_186"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9026762" version="SP_186"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000283887" version="SP_186" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005640" secondary="nuclear outer membrane" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004464" secondary="leukotriene-C4 synthase activity" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8N6P0" version="SP_150" refType="secondary-ac" refTypeAc="MI:0360"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2142688" version="SP_186"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000639087" version="SP_186" refType="transcript"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HV9" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4J7T" version="SP_186"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LEO" version="SP_186"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_665874.1"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48473N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" secondary="nuclear envelope" version="SP_186"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21175-1" id="3158870">
                <names>
                    <shortLabel>ltc4s-3</shortLabel>
                </names>
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                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-102970E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15647633" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21175-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3158867</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3158871">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647637" refType="identity" refTypeAc="MI:0356"/>
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                        <interactorRef>3158869</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="4896">
                                <names>
                                    <shortLabel>schpm</shortLabel>
                                    <fullName>Schizosaccharomyces pombe (fission yeast)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-21175-2" id="3158872">
                <names>
                    <shortLabel>ltc4s-4</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-102970E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21175-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3158868</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3158873">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647653" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3158869</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="4896">
                                <names>
                                    <shortLabel>schpm</shortLabel>
                                    <fullName>Schizosaccharomyces pombe (fission yeast)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Fission yeast</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
