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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3158699">
                <names>
                    <shortLabel>buck-2007-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17632520" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-68070X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15646989" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-8976" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nsmb1275" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="8355">
                        <names>
                            <shortLabel>xenla</shortLabel>
                            <fullName>Xenopus laevis (African clawed frog)</fullName>
                            <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>density sedimentation</shortLabel>
                        <fullName>cosedimentation through density gradient</fullName>
                        <alias typeAc="MI:1041" type="synonym">density sedimentation</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0029" refType="identity" refTypeAc="MI:0356"/>
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                        <secondaryRef db="pubmed" dbAc="MI:0446" id="10410796" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>weight autoradiogra</shortLabel>
                        <fullName>molecular weight estimation by autoradiography</fullName>
                        <alias typeAc="MI:1041" type="synonym">weight autoradiogra</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0821" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218638" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Buck TM., Wagner J., Grund S., Skach WR.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-68070X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Buck TM.,  Wagner J.,  Grund S.,  Skach WR.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3158700">
                <names>
                    <shortLabel>buck-2007-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17632520" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-68071X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15647012" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nsmb1275" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="8355">
                        <names>
                            <shortLabel>xenla</shortLabel>
                            <fullName>Xenopus laevis (African clawed frog)</fullName>
                            <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>weight autoradiogra</shortLabel>
                        <fullName>molecular weight estimation by autoradiography</fullName>
                        <alias typeAc="MI:1041" type="synonym">weight autoradiogra</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0821" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218638" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Buck TM., Wagner J., Grund S., Skach WR.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-68071X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Buck TM.,  Wagner J.,  Grund S.,  Skach WR.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3158701">
                <names>
                    <shortLabel>aqp1_human</shortLabel>
                    <fullName>Aquaporin-1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Aquaporin-CHIP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Water channel protein for red blood cells and kidney proximal tubule</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Urine water channel</alias>
                    <alias typeAc="MI:0301" type="gene name">AQP1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CHIP28</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P29972" version="SP_90" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_230"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-432047" version="SP_230"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006972" secondary="hyperosmotic response" version="SP_230"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TDC1" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015696" secondary="ammonium transport" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043154" secondary="negative regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031965" secondary="nuclear membrane" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071300" secondary="cellular response to retinoic acid" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022357" version="SP_230"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_230"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031526" secondary="brush border membrane" version="SP_230"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_230"/>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-8976-1" id="3158702">
                <names>
                    <shortLabel>aqp1-6</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-59088E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15647000" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-8976-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3158699</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3158703">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647004" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3158701</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3158704">
                                <names>
                                    <shortLabel>P29972:p.[Asn49Lys;Lys51Leu]</shortLabel>
                                    <fullName>M49K, K51L mutation</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647005" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>mutation disrupting strength</shortLabel>
                                        <fullName>mutation disrupting interaction strength</fullName>
                                        <alias typeAc="MI:1041" type="synonym">mutation disrupting strength</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1128" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-5528001" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>substitut analysis</shortLabel>
                                        <fullName>substitution analysis</fullName>
                                        <alias typeAc="MI:1041" type="synonym">substitut analysis</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0810" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218575" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="51"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="51"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="49"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="49"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="3158705">
                                <names>
                                    <shortLabel>P29972:p.[Asn49Lys;Lys51Leu;Asp185Asn]</shortLabel>
                                    <fullName>M49K, K51L, D185N mutation</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647008" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>mutation disrupting strength</shortLabel>
                                        <fullName>mutation disrupting interaction strength</fullName>
                                        <alias typeAc="MI:1041" type="synonym">mutation disrupting strength</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1128" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-5528001" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>substitut analysis</shortLabel>
                                        <fullName>substitution analysis</fullName>
                                        <alias typeAc="MI:1041" type="synonym">substitut analysis</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0810" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218575" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="51"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="51"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="49"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="49"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="185"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="185"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8355">
                                <names>
                                    <shortLabel>xenla</shortLabel>
                                    <fullName>Xenopus laevis (African clawed frog)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-8976-2" id="3158706">
                <names>
                    <shortLabel>aqp1-aqp1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-59088E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15647023" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-8976-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3158700</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3158707">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647036" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3158701</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8355">
                                <names>
                                    <shortLabel>xenla</shortLabel>
                                    <fullName>Xenopus laevis (African clawed frog)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3158708">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647027" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3158701</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3158709">
                                <names>
                                    <shortLabel>Myc Tag</shortLabel>
                                    <fullName>Myc Tag</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647028" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>myc tag</shortLabel>
                                        <fullName>myc tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">EUKLISEED epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">EUKLISEED epitope tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0522" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456561" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>predetermined featur</shortLabel>
                                        <fullName>predetermined feature</fullName>
                                        <alias typeAc="MI:1041" type="synonym">predetermined featur</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0823" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218592" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="120"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="120"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="3158710">
                                <names>
                                    <shortLabel>P29972:p.Asn49Lys</shortLabel>
                                    <fullName>M49K mutation</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647030" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>mutation disrupting strength</shortLabel>
                                        <fullName>mutation disrupting interaction strength</fullName>
                                        <alias typeAc="MI:1041" type="synonym">mutation disrupting strength</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1128" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-5528001" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>substitut analysis</shortLabel>
                                        <fullName>substitution analysis</fullName>
                                        <alias typeAc="MI:1041" type="synonym">substitut analysis</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0810" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218575" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="49"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="49"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="3158711">
                                <names>
                                    <shortLabel>P29972:p.[Asn49Lys;Lys51Leu;Asp185Asn]</shortLabel>
                                    <fullName>M49K, K51L, D185N mutation</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15647032" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>mutation disrupting strength</shortLabel>
                                        <fullName>mutation disrupting interaction strength</fullName>
                                        <alias typeAc="MI:1041" type="synonym">mutation disrupting strength</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1128" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-5528001" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>substitut analysis</shortLabel>
                                        <fullName>substitution analysis</fullName>
                                        <alias typeAc="MI:1041" type="synonym">substitut analysis</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0810" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218575" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="51"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="51"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="49"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="49"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="185"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="185"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8355">
                                <names>
                                    <shortLabel>xenla</shortLabel>
                                    <fullName>Xenopus laevis (African clawed frog)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
