DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ hwang-2007-1 ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261508X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-2 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261513X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-3 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261515X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-4 ecolx Escherichia coli light scattering light scattering predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261519X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-5 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261509X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-6 ecolx Escherichia coli crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261516X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-7 ecolx Escherichia coli crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261518X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-8 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261511X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-9 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261514X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-10 in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261517X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-11 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261512X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation hwang-2007-12 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. DIP original experiment: DIP-261510X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Hwang E., Ryu KS., Pääkkönen K., Güntert P., Cheong HK., Lim DS., Lee JO., Jeon YH., Cheong C. Only protein-protein interactions imex curation q13043-1 Serine/threonine-protein kinase 4 STK4 KRS2 MST1 Mammalian STE20-like protein kinase 1 STE20-like kinase MST1 Serine/threonine-protein kinase Krs-2 protein protein human Homo sapiens Human METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF sav1_human Protein salvador homolog 1 SAV1 WW45 45 kDa WW domain protein protein protein human Homo sapiens Human MLSRKKTKNEVSKPAEVQGKYVKKETSPLLRNLMPSFIRHGPTIPRRTDICLPDSSPNAFSTSGDVVSRNQSFLRTPIQRTPHEIMRRESNRLSAPSYLARSLADVPREYGSSQSFVTEVSFAVENGDSGSRYYYSDNFFDGQRKRPLGDRAHEDYRYYEYNHDLFQRMPQNQGRHASGIGRVAATSLGNLTNHGSEDLPLPPGWSVDWTMRGRKYYIDHNTNTTHWSHPLEREGLPPGWERVESSEFGTYYVDHTNKKAQYRHPCAPSVPRYDQPPPVTYQPQQTERNQSLLVPANPYHTAEIPDWLQVYARAPVKYDHILKWELFQLADLDTYQGMLKLLFMKELEQIVKMYEAYRQALLTELENRKQRQQWYAQQHGKNF q8www0-1 Ras association domain-containing protein 5 A NORE1A RASSF5 NORE1 RAPL New ras effector 1 Regulator for cell adhesion and polarization enriched in lymphoid tissues protein protein human Homo sapiens Human MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG stk4-6 3156649 N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false sav1-stk4-2 3156650 N/A 3156662 unspecified role unspecified role unspecified role unspecified role Region 321-373 Region 321-373 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rassf5-1 3156651 N/A 3156663 unspecified role unspecified role unspecified role unspecified role Region 366-413 Region 366-413 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false stk4-2 3156652 N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rassf5-stk4-1 3156653 N/A 3156663 unspecified role unspecified role unspecified role unspecified role Region 366-413 Region 366-413 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false stk4-3 3156654 N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rassf5-2 3156655 N/A 3156663 unspecified role unspecified role unspecified role unspecified role Region 366-413 Region 366-413 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false stk4-4 3156656 N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false sav1-1 3156657 N/A 3156662 unspecified role unspecified role unspecified role unspecified role Region 321-373 Region 321-373 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rassf5-stk4-2 3156658 N/A 3156663 unspecified role unspecified role unspecified role unspecified role Region 366-413 Region 366-413 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rassf5-stk4-3 3156659 N/A 3156663 unspecified role unspecified role unspecified role unspecified role Region 366-413 Region 366-413 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false sav1-stk4-3 3156660 N/A 3156662 unspecified role unspecified role unspecified role unspecified role Region 321-373 Region 321-373 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3156661 unspecified role unspecified role unspecified role unspecified role Region 432-480 Region 432-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false