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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3156092">
                <names>
                    <shortLabel>lee-2007-12</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17486097" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-255303X" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21850" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>protein kinase assay</shortLabel>
                        <fullName>protein kinase assay</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0424" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>weight autoradiogra</shortLabel>
                        <fullName>molecular weight estimation by autoradiography</fullName>
                        <alias typeAc="MI:1041" type="synonym">weight autoradiogra</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0821" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218638" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Lee JH., Koh H., Kim M., Kim Y., Lee SY., Karess RE., Lee SH., Shong M., Kim JM., Kim J., Chung J.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-255303X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Energy-dependent regulation of cell structure by AMP-activated protein kinase.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Lee JH.,  Koh H.,  Kim M.,  Kim Y.,  Lee SY.,  Karess RE.,  Lee SH.,  Shong M.,  Kim JM.,  Kim J.,  Chung J.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3156093">
                <names>
                    <shortLabel>myl9_human</shortLabel>
                    <fullName>Myosin regulatory light polypeptide 9</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Myosin regulatory light chain 9</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Myosin regulatory light chain MRLC1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Myosin regulatory light chain 2, smooth muscle isoform</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Myosin RLC</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MLC-2C</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">20 kDa myosin light chain</alias>
                    <alias typeAc="MI:0301" type="gene name">MYL9</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MRLC1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MYRL2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MLC2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P24844" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_189"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006088.2"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_852667.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5627123" version="SP_189"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070527" secondary="platelet aggregation" version="SP_189"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000101335" version="SP_189" refType="gene"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018247" version="SP_189"/>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
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                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD</sequence>
            </interactor>
            <interactor id="3156094">
                <names>
                    <shortLabel>aapk1_human</shortLabel>
                    <fullName>5'-AMP-activated protein kinase catalytic subunit alpha-1</fullName>
                    <alias typeAc="MI:0301" type="gene name">PRKAA1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">AMPK1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Tau-protein kinase PRKAA1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Acetyl-CoA carboxylase kinase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Hydroxymethylglutaryl-CoA reductase kinase</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674" secondary="protein serine/threonine kinase activity" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070507" secondary="regulation of microtubule cytoskeleton organization" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046318" secondary="negative regulation of glucosylceramide biosynthetic process" version="SP_226"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-39973N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030425" secondary="dendrite" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0062028" secondary="regulation of stress granule assembly" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061744" secondary="motor behavior" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048511" secondary="rhythmic process" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050405" secondary="[acetyl-CoA carboxylase] kinase activity" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035690" secondary="cellular response to drug" version="SP_226"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6C9G" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009631" secondary="cold acclimation" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071333" secondary="cellular response to glucose stimulus" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046627" secondary="negative regulation of insulin receptor signaling pathway" version="SP_226"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047322" secondary="[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity" version="SP_226"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21850-1" id="3156095">
                <names>
                    <shortLabel>myl9-prkaa1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-192282E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15636046" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21850-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3156092</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3156096">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15636053" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3156093</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme target</shortLabel>
                                <fullName>enzyme target</fullName>
                                <alias typeAc="MI:0303" type="go synonym">substrate</alias>
                                <alias typeAc="MI:1041" type="synonym">substrate</alias>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3156097">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15636050" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3156094</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme</shortLabel>
                                <fullName>enzyme</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3156098">
                                <names>
                                    <shortLabel>Region 1-550</shortLabel>
                                    <fullName>Region 1-550</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15636051" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="1"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="550"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>phosphorylation</shortLabel>
                        <fullName>phosphorylation reaction</fullName>
                        <alias typeAc="MI:1041" type="synonym">phosphorylation</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0217" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0039" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0033" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0034" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="go" dbAc="MI:0448" id="GO:0016310" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49922" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0035" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0222" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0037" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0036" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="resid" dbAc="MI:0248" id="AA0038" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
