DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ fenalti-2007-1 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Fenalti G., Law RH., Buckle AM., Langendorf C., Tuck K., Rosado CJ., Faux NG., Mahmood K., Hampe CS., Banga JP., Wilce M., Schmidberger J., Rossjohn J., El-Kabbani O., Pike RN., Smith AI., Mackay IR., Rowley MJ., Whisstock JC. DIP original experiment: DIP-66662X Nature structural & molecular biology 2007 IMEx GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Fenalti G., Law RH., Buckle AM., Langendorf C., Tuck K., Rosado CJ., Faux NG., Mahmood K., Hampe CS., Banga JP., Wilce M., Schmidberger J., Rossjohn J., El-Kabbani O., Pike RN., Smith AI., Mackay IR., Rowley MJ., Whisstock JC. Only protein-protein interactions imex curation fenalti-2007-2 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Fenalti G., Law RH., Buckle AM., Langendorf C., Tuck K., Rosado CJ., Faux NG., Mahmood K., Hampe CS., Banga JP., Wilce M., Schmidberger J., Rossjohn J., El-Kabbani O., Pike RN., Smith AI., Mackay IR., Rowley MJ., Whisstock JC. DIP original experiment: DIP-66663X Nature structural & molecular biology 2007 IMEx GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Fenalti G., Law RH., Buckle AM., Langendorf C., Tuck K., Rosado CJ., Faux NG., Mahmood K., Hampe CS., Banga JP., Wilce M., Schmidberger J., Rossjohn J., El-Kabbani O., Pike RN., Smith AI., Mackay IR., Rowley MJ., Whisstock JC. Only protein-protein interactions imex curation dce1_human Glutamate decarboxylase 1 Glutamate decarboxylase 67 kDa isoform 67 kDa glutamic acid decarboxylase GAD1 GAD GAD67 protein protein human Homo sapiens Human MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL dce2_human Glutamate decarboxylase 2 GAD2 GAD65 65 kDa glutamic acid decarboxylase Glutamate decarboxylase 65 kDa isoform protein protein human Homo sapiens Human MASPGSGFWSFGSEDGSGDSENPGTARAWCQVAQKFTGGIGNKLCALLYGDAEKPAESGGSQPPRAAARKAACACDQKPCSCSKVDVNYAFLHATDLLPACDGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWYIPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL gad1-1 3154257 N/A 3154259 unspecified role unspecified role neutral component neutral component 90-594 binding region 90-594 binding region sufficient to bind sufficient binding region sufficient to bind predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction false false false gad2-1 3154258 N/A 3154260 unspecified role unspecified role neutral component neutral component 84-585 binding region 84-585 binding region sufficient to bind sufficient binding region sufficient to bind predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction false false false