DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ guo-2007-5 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Guo L., Han A., Bates DL., Cao J., Chen L. DIP original experiment: DIP-261167X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains. Guo L., Han A., Bates DL., Cao J., Chen L. Only protein-protein interactions imex curation guo-2007-6 ecolx Escherichia coli crosslink cross-linking study crosslink predetermined predetermined participant predetermined Guo L., Han A., Bates DL., Cao J., Chen L. DIP original experiment: DIP-261170X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains. Guo L., Han A., Bates DL., Cao J., Chen L. Only protein-protein interactions imex curation guo-2007-7 ecolx Escherichia coli light scattering light scattering predetermined predetermined participant predetermined Guo L., Han A., Bates DL., Cao J., Chen L. DIP original experiment: DIP-261168X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains. Guo L., Han A., Bates DL., Cao J., Chen L. Only protein-protein interactions imex curation guo-2007-8 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Guo L., Han A., Bates DL., Cao J., Chen L. DIP original experiment: DIP-261169X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains. Guo L., Han A., Bates DL., Cao J., Chen L. Only protein-protein interactions imex curation hdac4_human Histone deacetylase 4 HDAC4 KIAA0288 protein protein human Homo sapiens Human MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEEEPPL hdac4-1 3153871 N/A 3153875 unspecified role unspecified role unspecified role unspecified role Region 62-153 Region 62-153 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false hdac4-4 3153872 N/A 3153875 unspecified role unspecified role unspecified role unspecified role Region 62-153 Region 62-153 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false hdac4-5 3153873 N/A 3153875 unspecified role unspecified role unspecified role unspecified role Region 62-153 Region 62-153 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false P56524:p.His97Phe H97F mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false P56524:p.Phe93Asp F93D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false hdac4-6 3153874 N/A 3153875 unspecified role unspecified role unspecified role unspecified role Region 62-153 Region 62-153 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false P56524:p.His97Phe H97F mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false P56524:p.Phe93Asp F93D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false