DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ sugihara-2007-1 in vitro In vitro pull down pull down autoradiography autoradiography Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. DIP original experiment: DIP-261141X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation. Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. Only protein-protein interactions imex curation sugihara-2007-2 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. DIP original experiment: DIP-261143X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation. Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. Only protein-protein interactions imex curation sugihara-2007-3 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. DIP original experiment: DIP-261142X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation. Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. Only protein-protein interactions imex curation sugihara-2007-4 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. DIP original experiment: DIP-261144X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation. Sugihara K., Sugiyama D., Byrne J., Wolf DP., Lowitz KP., Kobayashi Y., Kabir-Salmani M., Nadano D., Aoki D., Nozawa S., Nakayama J., Mustelin T., Ruoslahti E., Yamaguchi N., Fukuda MN. Only protein-protein interactions imex curation byst_human Bystin BYSL ENP1 protein protein human Homo sapiens Human MPKFKAARGVGGQEKHAPLADQILAGNAVRAGVREKRRGRGTGEAEEEYVGPRLSRRILQQARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQDGSDDEDEEWPTLEKAATMTAAGHHAEVVVDPEDERAIEMFMNKNPPARRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDVAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLGFRTEKRELPVLWHQCLLTLVQRYKADLATDQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVPITVE erbb4_human Receptor tyrosine-protein kinase erbB-4 ERBB4 HER4 p180erbB4 Proto-oncogene-like protein c-ErbB-4 Tyrosine kinase-type cell surface receptor HER4 protein protein human Homo sapiens Human MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV troap_human Tastin TROAP Trophinin-assisting protein Trophinin-associated protein protein protein human Homo sapiens Human MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQRPLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEFVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLTAIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP erbb4-bysl-1 3153686 N/A 3153690 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3153691 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false erbb4-bysl-2 3153687 N/A 3153690 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3153692 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3153691 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false erbb4-bysl-3 3153688 N/A 3153691 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3153692 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3153690 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro association association false false false erbb4-troap-1 3153689 N/A 3153692 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3153691 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false