DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ mittal-2006-1 in vitro In vitro acetylase assay acetylase assay predetermined predetermined participant predetermined Mittal R., Peak-Chew SY., McMahon HT. DIP original experiment: DIP-264210X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling. Mittal R., Peak-Chew SY., McMahon HT. Only protein-protein interactions imex curation mittal-2006-2 in vitro In vitro acetylase assay acetylase assay weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Mittal R., Peak-Chew SY., McMahon HT. DIP original experiment: DIP-264211X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling. Mittal R., Peak-Chew SY., McMahon HT. Only protein-protein interactions imex curation mp2k2_human Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 MEK2 MKK2 PRKMK2 ERK activator kinase 2 MAPK/ERK kinase 2 protein protein human Homo sapiens Human MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV yopj_yerps Serine/threonine-protein acetyltransferase YopJ Virulence factor YopJ pYV0098 yopJ protein protein yerps Yersinia pseudotuberculosis serotype I MIGPISQINISGGLSEKETSSLISNEELKNIITQLETDISDGSWFHKNYSRMDVEVMPALVIQANNKYPEMNLNLVTSPLDLSIEIKNVIENGVRSSRFIINMGEGGIHFSVIDYKHINGKTSLILFEPANFNSMGPAMLAIRTKTAIERYQLPDCHFSMVEMDIQRSSSECGIFSFALAKKLYIERDSLLKIHEDNIKGILSDGENPLPHDKLDPYLPVTFYKHTQGKKRLNEYLNTNPQGVGTVVNKKNETIVNRFDNNKSIVDGKELSVSVHKKRIAEYKTLLKV map2k2-yopj-1 3150711 n/a 3150713 enzyme target enzyme target substrate substrate unspecified role unspecified role ecolx Escherichia coli N/A 3150714 enzyme enzyme unspecified role unspecified role P0DUC9:p.Cys172Ala C172A mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli acetylation acetylation reaction acetylation false false false yopj-1 3150712 N/A 3150714 putative self putative self unspecified role unspecified role P0DUC9:p.Cys172Ala C172A mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli acetylation acetylation reaction acetylation false false false