<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3149360">
                <names>
                    <shortLabel>ambati-2006-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17051153" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-254000X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15606878" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21446" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature05249" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse</shortLabel>
                            <fullName>Mus musculus</fullName>
                            <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ambati BK., Nozaki M., Singh N., Takeda A., Jani PD., Suthar T., Albuquerque RJ., Richter E., Sakurai E., Newcomb MT., Kleinman ME., Caldwell RB., Lin Q., Ogura Y., Orecchia A., Samuelson DA., Agnew DW., St Leger J., Green WR., Mahasreshti PJ., Curiel DT., Kwan D., Marsh H., Ikeda S., Leiper LJ., Collinson JM., Bogdanovich S., Khurana TS., Shibuya M., Baldwin ME., Ferrara N., Gerber HP., De Falco S., Witta J., Baffi JZ., Raisler BJ., Ambati J.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-254000X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2006</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Corneal avascularity is due to soluble VEGF receptor-1.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Ambati BK.,  Nozaki M.,  Singh N.,  Takeda A.,  Jani PD.,  Suthar T.,  Albuquerque RJ.,  Richter E.,  Sakurai E.,  Newcomb MT.,  Kleinman ME.,  Caldwell RB.,  Lin Q.,  Ogura Y.,  Orecchia A.,  Samuelson DA.,  Agnew DW.,  St Leger J.,  Green WR.,  Mahasreshti PJ.,  Curiel DT.,  Kwan D.,  Marsh H.,  Ikeda S.,  Leiper LJ.,  Collinson JM.,  Bogdanovich S.,  Khurana TS.,  Shibuya M.,  Baldwin ME.,  Ferrara N.,  Gerber HP.,  De Falco S.,  Witta J.,  Baffi JZ.,  Raisler BJ.,  Ambati J.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3149361">
                <names>
                    <shortLabel>vgfr1_mouse</shortLabel>
                    <fullName>Vascular endothelial growth factor receptor 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Tyrosine-protein kinase receptor FLT</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fms-like tyrosine kinase 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Embryonic receptor kinase 2</alias>
                    <alias typeAc="MI:0301" type="gene name">Flt1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Emrk2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Flt</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Vegfr1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P35969" version="SP_86" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" secondary="angiogenesis" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905563" secondary="negative regulation of vascular endothelial cell proliferation" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001245" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043406" secondary="positive regulation of MAP kinase activity" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048514" secondary="blood vessel morphogenesis" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013151" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020635" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002244" secondary="hematopoietic progenitor cell differentiation" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048010" secondary="vascular endothelial growth factor receptor signaling pathway" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990384" secondary="hyaloid vascular plexus regression" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013098" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007169" secondary="transmembrane receptor protein tyrosine kinase signaling pathway" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003598" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901534" secondary="positive regulation of hematopoietic progenitor cell differentiation" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046777" secondary="protein autophosphorylation" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_203"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-194306" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001824" version="SP_203"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O55094" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P35969"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048597" secondary="post-embryonic camera-type eye morphogenesis" version="SP_203"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-195399" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010863" secondary="positive regulation of phospholipase C activity" version="SP_203"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-39359N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036332" secondary="placental growth factor-activated receptor activity" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019838" secondary="growth factor binding" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035924" secondary="cellular response to vascular endothelial growth factor stimulus" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005021" secondary="vascular endothelial growth factor-activated receptor activity" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008266" version="SP_203"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1554752" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045766" secondary="positive regulation of angiogenesis" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009135" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014068" secondary="positive regulation of phosphatidylinositol 3-kinase signaling" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002548" secondary="monocyte chemotaxis" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036323" secondary="vascular endothelial growth factor receptor-1 signaling pathway" version="SP_203"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_034358.2"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q61517" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001569" secondary="branching involved in blood vessel morphogenesis" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004714" secondary="transmembrane receptor protein tyrosine kinase activity" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002040" secondary="sprouting angiogenesis" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018108" secondary="peptidyl-tyrosine phosphorylation" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043552" secondary="positive regulation of phosphatidylinositol 3-kinase activity" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030335" secondary="positive regulation of cell migration" version="SP_203"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041348" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048598" secondary="embryonic morphogenesis" version="SP_203"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015629" secondary="actin cytoskeleton" version="SP_203"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MVSCWDTAVLPYALLGCLLLTGYGSGSKLKVPELSLKGTQHVMQAGQTLFLKCRGEAAHSWSLPTTVSQEDKRLSITPPSACGRDNRQFCSTLTLDTAQANHTGLYTCRYLPTSTSKKKKAESSIYIFVSDAGSPFIEMHTDIPKLVHMTEGRQLIIPCRVTSPNVTVTLKKFPFDTLTPDGQRITWDSRRGFIIANATYKEIGLLNCEATVNGHLYQTNYLTHRQTNTILDVQIRPPSPVRLLHGQTLVLNCTATTELNTRVQMSWNYPGKATKRASIRQRIDRSHSHNNVFHSVLKINNVESRDKGLYTCRVKSGSSFQSFNTSVHVYEKGFISVKHRKQPVQETTAGRRSYRLSMKVKAFPSPEIVWLKDGSPATLKSARYLVHGYSLIIKDVTTEDAGDYTILLGIKQSRLFKNLTATLIVNVKPQIYEKSVSSLPSPPLYPLGSRQVLTCTVYGIPRPTITWLWHPCHHNHSKERYDFCTENEESFILDPSSNLGNRIESISQRMTVIEGTNKTVSTLVVADSQTPGIYSCRAFNKIGTVERNIKFYVTDVPNGFHVSLEKMPAEGEDLKLSCVVNKFLYRDITWILLRTVNNRTMHHSISKQKMATTQDYSITLNLVIKNVSLEDSGTYACRARNIYTGEDILRKTEVLVRDSEAPHLLQNLSDYEVSISGSTTLDCQARGVPAPQITWFKNNHKIQQEPGIILGPGNSTLFIERVTEEDEGVYRCRATNQKGAVESAAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFIRKLKRSSSEVKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYLKSKRDLFCLNKDAALHMELKKESLEPGLEQGQKPRLDSVSSSSVTSSSFPEDRSVSDVEGDEDYSEISKQPLTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQANVQQDGKDYIPLNAILTRNSSFTYSTPTFSEDLFKDGFADPHFHSGSSDDVRYVNAFKFMSLERIKTFEELSPNSTSMFEDYQLDTSTLLGSPLLKRFTWTETKPKASMKIDLRIASKSKEAGLSDLPRPSFCFSSCGHIRPVQDDESELGKESCCSPPPDYNSVVLYSSPPA</sequence>
            </interactor>
            <interactor id="3149362">
                <names>
                    <shortLabel>vegfa_mouse</shortLabel>
                    <fullName>Vascular endothelial growth factor A</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Vascular permeability factor</alias>
                    <alias typeAc="MI:0301" type="gene name">Vegfa</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Vegf</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q00731" version="SP_76" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030335" secondary="positive regulation of cell migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042088" secondary="T-helper 1 type immune response" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043184" secondary="vascular endothelial growth factor receptor 2 binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050679" secondary="positive regulation of epithelial cell proliferation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008083" secondary="growth factor activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903589" secondary="positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061430" secondary="bone trabecula morphogenesis" version="SP_195"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6GT23" version="SP_76" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043069" secondary="negative regulation of programmed cell death" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043536" secondary="positive regulation of blood vessel endothelial cell migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900745" secondary="positive regulation of p38MAPK cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001968" secondary="fibronectin binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019838" secondary="growth factor binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051272" secondary="positive regulation of cellular component movement" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901492" secondary="positive regulation of lymphangiogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060982" secondary="coronary artery morphogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060319" secondary="primitive erythrocyte differentiation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051781" secondary="positive regulation of cell division" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010749" secondary="regulation of nitric oxide mediated signal transduction" version="SP_195"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001020421.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005912" secondary="adherens junction" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048010" secondary="vascular endothelial growth factor receptor signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031334" secondary="positive regulation of protein-containing complex assembly" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036303" secondary="lymph vessel morphogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045785" secondary="positive regulation of cell adhesion" version="SP_195"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001103738.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007399" secondary="nervous system development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002575" secondary="basophil chemotaxis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022408" secondary="negative regulation of cell-cell adhesion" version="SP_195"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-444774" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0040008" secondary="regulation of growth" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900086" secondary="positive regulation of peptidyl-tyrosine autophosphorylation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007595" secondary="lactation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030324" secondary="lung development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001541" secondary="ovarian follicle development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032147" secondary="activation of protein kinase activity" version="SP_195"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029034" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001944" secondary="vasculature development" version="SP_195"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001303970.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001273985.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090037" secondary="positive regulation of protein kinase C signaling" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905278" secondary="positive regulation of epithelial tube formation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031077" secondary="post-embryonic camera-type eye development" version="SP_195"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q66S31" version="SP_76" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001569" secondary="branching involved in blood vessel morphogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901215" secondary="negative regulation of neuron death" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901727" secondary="positive regulation of histone deacetylase activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042056" secondary="chemoattractant activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000048" secondary="negative regulation of cell-cell adhesion mediated by cadherin" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043129" secondary="surfactant homeostasis" version="SP_195"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-195399"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060749" secondary="mammary gland alveolus development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033138" secondary="positive regulation of peptidyl-serine phosphorylation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045599" secondary="negative regulation of fat cell differentiation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060948" secondary="cardiac vascular smooth muscle cell development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" secondary="cytokine activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003169" secondary="coronary vein morphogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071542" secondary="dopaminergic neuron differentiation" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090190" secondary="positive regulation of branching involved in ureteric bud morphogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002052" secondary="positive regulation of neuroblast proliferation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009967" secondary="positive regulation of signal transduction" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045669" secondary="positive regulation of osteoblast differentiation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005161" secondary="platelet-derived growth factor receptor binding" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001568" secondary="blood vessel development" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060426" secondary="lung vasculature development" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030141" secondary="secretory granule" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008201" secondary="heparin binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007498" secondary="mesoderm development" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060326" secondary="cell chemotaxis" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008360" secondary="regulation of cell shape" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903572" secondary="positive regulation of protein kinase D signaling" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071679" secondary="commissural neuron axon guidance" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036324" secondary="vascular endothelial growth factor receptor-2 signaling pathway" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060754" secondary="positive regulation of mast cell chemotaxis" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120162" secondary="positive regulation of cold-induced thermogenesis" version="SP_195"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-114608"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901165" secondary="positive regulation of trophoblast cell migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000573" secondary="positive regulation of DNA biosynthetic process" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005604" secondary="basement membrane" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035148" secondary="tube formation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048255" secondary="mRNA stabilization" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" secondary="angiogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097475" secondary="motor neuron migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038191" secondary="neuropilin binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903392" secondary="negative regulation of adherens junction organization" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" secondary="in utero embryonic development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043542" secondary="endothelial cell migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097533" secondary="cellular stress response to acid chemical" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043183" secondary="vascular endothelial growth factor receptor 1 binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002042" secondary="cell migration involved in sprouting angiogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903141" secondary="negative regulation of establishment of endothelial barrier" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050927" secondary="positive regulation of positive chemotaxis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005172" secondary="vascular endothelial growth factor receptor binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031982" secondary="vesicle" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048018" secondary="receptor ligand activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002040" secondary="sprouting angiogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060346" secondary="bone trabecula formation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038084" secondary="vascular endothelial growth factor signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030225" secondary="macrophage differentiation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902966" secondary="positive regulation of protein localization to early endosome" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001822" secondary="kidney development" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048593" secondary="camera-type eye morphogenesis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038089" secondary="positive regulation of cell migration by vascular endothelial growth factor signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901532" secondary="regulation of hematopoietic progenitor cell differentiation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" secondary="cell population proliferation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051897" secondary="positive regulation of protein kinase B signaling" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045779" secondary="negative regulation of bone resorption" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048666" secondary="neuron development" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043406" secondary="positive regulation of MAP kinase activity" version="SP_195"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050918" secondary="positive chemotaxis" version="SP_195"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023581" version="SP_195"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MNFLLSWVHWTLALLLYLHHAKWSQAAPTTEGEQKSHEVIKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNITMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKKSVRGKGKGQKRKRKKSRFKSWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21446-1" id="3149363">
                <names>
                    <shortLabel>vegfa-flt1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-191604E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15606889" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21446-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3149360</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3149364">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15606894" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3149361</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3149365">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15606893" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3149362</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="10090">
                                <names>
                                    <shortLabel>mouse</shortLabel>
                                    <fullName>Mus musculus</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
