DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ xiao-2006-5 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. DIP original experiment: DIP-264013X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. Only protein-protein interactions imex curation xiao-2006-6 chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. DIP original experiment: DIP-264016X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. Only protein-protein interactions imex curation xiao-2006-7 in vitro In vitro pull down pull down autoradiography autoradiography Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. DIP original experiment: DIP-264014X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. Only protein-protein interactions imex curation xiao-2006-8 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. DIP original experiment: DIP-264017X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. Only protein-protein interactions imex curation xiao-2006-9 chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. DIP original experiment: DIP-264015X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Xiao S., Li D., Zhu HQ., Song MG., Pan XR., Jia PM., Peng LL., Dou AX., Chen GQ., Chen SJ., Chen Z., Tong JH. Only protein-protein interactions imex curation csn5_human COP9 signalosome complex subunit 5 Jun activation domain-binding protein 1 COPS5 CSN5 JAB1 protein protein human Homo sapiens Human MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQINIS ifit3_human Interferon-induced protein with tetratricopeptide repeats 3 ISG-60 CIG49 Retinoic acid-induced gene G protein Interferon-induced protein with tetratricopeptide repeats 4 Interferon-induced 60 kDa protein IFIT3 IFI60 IFIT4 CIG-49 ISG60 protein protein human Homo sapiens Human MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG cdn1b_human Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor p27 p27Kip1 CDKN1B KIP1 protein protein human Homo sapiens Human MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT ifit3-cops5-1 3149300 N/A 3149305 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3149306 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false cops5-ifit3-1 3149301 N/A 3149305 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey N/A 3149306 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey physical association physical association false false false ifit3-cops5-2 3149302 N/A 3149305 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3149306 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false cdkn1b-ub-1 3149303 N/A 3149307 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3149308 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false ifit3-cops5-3 3149304 N/A 3149305 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey N/A 3149306 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey physical association physical association false false false