DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ russell-2006-1 human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Russell RJ., Haire LF., Stevens DJ., Collins PJ., Lin YP., Blackburn GM., Hay AJ., Gamblin SJ., Skehel JJ. DIP original experiment: DIP-254012X Nature 2006 IMEx The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Russell RJ., Haire LF., Stevens DJ., Collins PJ., Lin YP., Blackburn GM., Hay AJ., Gamblin SJ., Skehel JJ. Only protein-protein interactions imex curation russell-2006-2 chick Gallus gallus (Chicken) Chicken x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Russell RJ., Haire LF., Stevens DJ., Collins PJ., Lin YP., Blackburn GM., Hay AJ., Gamblin SJ., Skehel JJ. DIP original experiment: DIP-254013X Nature 2006 IMEx The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Russell RJ., Haire LF., Stevens DJ., Collins PJ., Lin YP., Blackburn GM., Hay AJ., Gamblin SJ., Skehel JJ. Only protein-protein interactions imex curation russell-2006-3 chick Gallus gallus (Chicken) Chicken x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Russell RJ., Haire LF., Stevens DJ., Collins PJ., Lin YP., Blackburn GM., Hay AJ., Gamblin SJ., Skehel JJ. DIP original experiment: DIP-254014X Nature 2006 IMEx The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Russell RJ., Haire LF., Stevens DJ., Collins PJ., Lin YP., Blackburn GM., Hay AJ., Gamblin SJ., Skehel JJ. Only protein-protein interactions imex curation q6dpl2_9infa Neuraminidase NA protein protein influenza a virus (a/viet nam/1203/2004(h5n1)) Influenza A virus (A/Viet Nam/1203/2004(H5N1)) MNPNQKIITIGSICMVTGIVSLMLQIGNMISIWVSHSIHTGNQHQSEPISNTNFLTEKAVASVKLAGNSSLCPINGWAVYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPHRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASHKIFKMEKGKVVKSVELDAPNYHYEECSCYPNAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVFGDNPRPNDGTGSCGPVSSNGAYGVKGFSFKYGNGVWIGRTKSTNSRSGFEMIWDPNGWTETDSSFSVKQDIVAITDWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKESTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDK q6xv46_9infa Neuraminidase NA protein protein influenza a virus (a/mink/sweden/e12665/84(h10n4)) Influenza A virus (A/mink/Sweden/E12665/84(H10N4)) MNPNQKIITIGSVSIVLTTIGLLLQITSLCSIWFSHYNQVTQTNEQPCSNNTTNYYNETFVNVTNVQNNYTTITDPSTSQVIHYSSGKDLCPVKGWAPLSKDNGIRIGSRGEVFVIREPFISCSINECRTFFLTQGALLNDKHSNGTVKDRSPFRTLMSCPIGVAPSPSNSRFESVAWSATACSDGPGWLTIGITGPDATAVAVLKYNGIITDTLKSWKGNIMRTQESECVCQDEFCYTLITDGPSDAQAFYKILKIKKGKIVSVKDVDAPGFHFEECSCYPSGENVECVCRDNWRGSNRPWIRFNSDLDYQIGYVCSGVFGDNPRPMDSTGSCNSPINNGKGRYGVKGFSFRYGDGVWIGRTKSLESRSGFEMVWDANGWVSTDKDSNGVQDIIDNDNWSGYSGSFSIRGETTGRNCTVPCFWVEMIRGQPKEKTIWTSGSSIAFCGVNSDTTGWSWPDGALLPFDIDK nram_i63a3 Neuraminidase NA protein protein i63a3 Influenza A virus (strain A/Duck/Ukraine/1/1963 H3N8) MNPNQKIITIGSISLGLVVFNVLLHVVSIIVTVLVLGKGGNNGICNETVVREYNETVRIEKVTQWHNTNVVEYVPYWNGGTYMNNTEAICDAKGFAPFSKDNGIRIGSRGHIFVIREPFVSCSPIECRTFFLTQGSLLNDKHSNGTVKDRSPFRTLMSVEVGQSPNVYQARFEAVAWSATACHDGKKWMTVGVTGPDSKAVAVIHYGGVPTDVVNSWAGDILRTQESSCTCIQGDCYWVMTDGPANRQAQYRIYKANQGRIIGQTDISFNGGHIEECSCYPNDGKVECVCRDGWTGTNRPVLVISPDLSYRVGYLCAGIPSDTPRGEDTQFTGSCTSPMGNQGYGVKGFGFRQGTDVWMGRTISRTSRSGFEILRIKNGWTQTSKEQIRKQVVVDNLNWSGYSGSFTLPVELSGKDCLVPCFWVEMIRGKPEEKTIWTSSSSIVMCGVDYEVADWSWHDGAILPFDIDKM na-1 3147072 N/A 3147075 unspecified role unspecified role unspecified role unspecified role Region 63-449 Region 63-449 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human direct interaction direct interaction false false false na-2 3147073 N/A 3147076 unspecified role unspecified role unspecified role unspecified role Region 81-470 Region 81-470 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chick Gallus gallus (Chicken) Chicken direct interaction direct interaction false false false na-3 3147074 N/A 3147077 unspecified role unspecified role unspecified role unspecified role Region 81-470 Region 81-470 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chick Gallus gallus (Chicken) Chicken direct interaction direct interaction false false false