DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ monte-2006-1 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263417X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-2 in vitro In vitro pull down pull down autoradiography autoradiography Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263421X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-3 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263425X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-4 in vitro In vitro pull down pull down autoradiography autoradiography Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263419X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-5 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263423X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-6 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263426X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-7 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263418X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-8 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263422X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-9 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263420X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation monte-2006-10 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. DIP original experiment: DIP-263424X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Monte M., Simonatto M., Peche LY., Bublik DR., Gobessi S., Pierotti MA., Rodolfo M., Schneider C. Only protein-protein interactions imex curation maga2_human Melanoma-associated antigen 2 MAGEA2 MAGEA2B MAGE2 MAGEA2A MAGE2 MAGEA2 Cancer/testis antigen 1.2 MAGE-2 antigen protein protein human Homo sapiens Human MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE p53_human Cellular tumor antigen p53 TP53 P53 Tumor suppressor p53 Phosphoprotein p53 Antigen NY-CO-13 protein protein human Homo sapiens Human MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD hdac3_human Histone deacetylase 3 HDAC3 RPD3-2 SMAP45 protein protein human Homo sapiens Human MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI p73_human Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH tp53-magea2-1 3145859 N/A 3145869 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3145870 unspecified role unspecified role bait bait Region 1-298 Region 1-298 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human physical association physical association false false false magea2-hdac3-1 3145860 N/A 3145871 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3145869 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false tp53-magea2-2 3145861 N/A 3145870 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3145869 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false tp53-magea2-3 3145862 N/A 3145869 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3145870 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false hdac3-magea2-1 3145863 N/A 3145870 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3145871 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3145869 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false magea2-tp73-1 3145864 N/A 3145872 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3145869 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tp53-magea2-4 3145865 N/A 3145869 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3145870 unspecified role unspecified role bait bait Region 94-298 Region 94-298 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false magea2-hdac3-2 3145866 N/A 3145870 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3145871 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3145869 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false magea2-tp53-1 3145867 N/A 3145869 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3145870 unspecified role unspecified role prey prey Region 94-298 Region 94-298 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro direct interaction direct interaction false false false magea2-hdac3-3 3145868 N/A 3145871 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3145869 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false