UniProt UniProt http://www.uniprot.org murga_zamalloa-2009-1 bovin-retina Bovine retina retina retinal tissue anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu Molecular vision 2009 imex curation Only protein-protein interactions murga_zamalloa-2009-3 in vitro In vitro pull down pull down weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu Molecular vision 2009 imex curation Only protein-protein interactions murga_zamalloa-2009-2 mouse-retina Mus musculus retina retina retinal tissue anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu Molecular vision 2009 imex curation Only protein-protein interactions a7ywf3_bovin NPHP1 protein protein bovin Bos taurus (Bovine) Bovine MLARRQRDPLQSLQRRNQELKQQVDGLLFESRLKGALEASKRRDMYQRCIQLKQAIDENKNALQKLKKADEPAPVGNYYQKKEEEHNLLDKLTHQLQELAVSISRENVPETGALAEREEEENSDEEDEEEDDDEEESEESGGEDEETEEEEEEKQEGESQPEATSGEYIALGDFTAQQVGDLTFKKGEILCIIKKNSDGWWMAKNAKGNEGLIPKTYLEPYNKEGGQESSEGGSEEDTEVGDGTVDGAEVKQRTDSHWSAVRKAISEINTVDVLTAMGAIPAGFRPSTLFQLLEEGNQFRASYFLQPELTPSQLAFRDLMWDAKTGSIRSRPSRVSLILTLWSCKMIPLPGVSIQVLSRHVRLCLFDGSEVLSNIHTVRATWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSSPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDATGIPIPAKTYKLFLNGGTPYEKGVEVDPSVSRRAHGSVFHQLMTMRRQPQLLVKLRSLNRRSRSTLSLLPETLIGSMCCVHLLIFYRQILGDVLLKDRMSLNSADLISNPVLATFPKLLEESDIMDALRSSWAEKESTLKRSEKGDRELLKAVFLLVYHDCALPLLHSALLPPSRWAEEETEAARWKGIADFLKQNQENEGALQVLLSPEGVHEPFDISEQTYDFLGERRKNVT q9gmd3_bovin RPGR protein protein bovin Bos taurus (Bovine) Bovine KQEIIEKPKQHTTYTESDDSNEYENEEISPKVTEGRVYKQLLAQGMYAMPVAISMETFSDEDVGDDSDQQSPQTSTSAEGLQKGTFRHENKHDVYPLNTEEIEKESDEGQSQKDSEANEIVSEMESDLVKMTDLKDIRKTEENRKNTDTFFDDLPNRYMNIEDEEDKDFVKESKGDKQDMIFDSEQASIEEENSYLEGESESQQSIADGFQQSESIEFNSVEKDDDEVETNQNLWYSRTFIKQRHEEARHRLSRIMAKYEFKCDRLSRIPEEQEEDSEGSGVEEQEIEANEEECGEKEKEETALLSDDLTDRAEVSEGKGKLGGEAEHVPKGGGEGIRKEGNSGVEQRSRTGSEEGEEGEDMGEGVIESLGKGEKDLEEEEQEQKEREQGHQEERSTGRKEAGEREQGGGEGEEEADEEEGEEEKDKEKEEGKEKEEEEEQEGEGEELEEGRWQDGEEGEGKGDEEGQEGGREEEGDREGQEGEEEGEGEEAGEGEEEGEGEEEGEGEEEGEGEEAGEGEEAGEGKGREEEEKGEEGEGEEKVGGEEEEDGEGQEGEEEEEEEGDGEEEEEGDGEEQEAEGGEVEGDGEVEEVGDEEKEGDGEEEGDGEREGGTGEGDEEEQKGEEEEEGDGEGEEEGDGEGEEEGDGEGEEEGDGEEQEGEKEEDGEGEEEGDGEGEEGDGEGEEEGDGEGEEEGDGEGEEEGDGEEQEGEEEEDGEGEEEGDGEQEGEEEEEGGGDEGEEEGEGEEELEEGEGEEEGEAEGEEGEGEEEEGEGEKGGEGLGGEGEEGEEEGGERVEEGEGEREREGMEREEKEWVVRKRKEKENGRGEEKEEDENNEEEKGKCQETGNEESGRQGRKGGGRESKVSKIRGSGKYGKDRTHPKKFTTNREGKGKGHGVQRFKIPVQSKQLLVNGPPGSKKFWNNVLPHYLELK e1bjb5_bovin NPHP4 protein protein bovin Bos taurus (Bovine) Bovine MHDWHRIFDQNLLVPPHPQRARQPLKESTAFQCVLKWLDGPLIKQGVLELLSEVGCHLRVSLFDVTYRHFFGRTWRSSPRPAEPLTRQPARIVFNEPLYFHTSLNHPHIVAVVEVVVEGRRRDGTLQTLSCGFGILRIFSHKPESPTSTSQDKRLRLYHGSPRALLHPLLQDPIEQNKHMTLIENCSLQYTLRPHPLLEPVFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPLTCYLDDLFFTLYPSLEKFEEELLELVISDCFREAGSPLDVGTLEILERRLCVGVHNGLGFVQRPQVLVLVPELEVALTRSASFSRKVGSSSKASSGNQALVLRSRLRLPEMVRHPAFAIVFQLEYVFNSPSGADSNAASLSSLSSLACMHMVRWAVWNPSLEASSGQVMLPLQGGIQSNPSHCLVYKVPPASISSEEVKQVESGTVQFQYSLSPEEHPGTPTANASSPKAERRSFRKPPVSPSSPPASPSQGLTAAQDSPMGPGLSLSQLAASPPSPAPRRRSAKPSSQPPGSPVPSLVPGEFPLEGRISHLEADLSQTALALGTSAADHLQELPFTPVHAPIIAGTQTRSSGGKLSRASLALLQSAGFPEILDANKQPAEAVSPTDPVKFSPQKEESDCLQGNEIVLQFLAFSRVPQDEQAAPWPQTVYFTFQFYRFPPETTPRLQLVELADAGKTSSASLSHILAQIQKDGSFDAGSPGFQRKYLVDPGFLRPGEQRWFARYLAMQTLQIDVWDGDSLLLIGSAAVQLKHLLRQGRPAVQVSHELEVVATEYEQDAMVVSGDMTKFGCVRPIDVHTVVKGQLHLTLANVGHLCEQRVRSPSSLPPSRSRVISNDGVGNFMGGSLLTPGGPRLKNVVQAQKLADVDSELAALLFTQPRPGARGPQGINQEGDAVRRRKLERMRAVRLRECGLEPGRRGLGALAQQSLHAQHARDLQVIAAYRERTKAESIASALSTAITTQHTIHATLGAAEFFEFALRNPHNAQHMVTIEIDNPELSLILDGQEWRYFKDMADLHTPLEEDMFHLRGSLAPQLFLRPRETAHIPFKFQTFSVGPWASAQASAELRSEKDMDAGSPYKSSMMPTKHAKVLFRAGSGKPLAVLCLTVELQPHVVDQVFRFHHPELTFLKKAIRLPPWHTLPGAPVGTSSEDPPFHVRCSDPNIICETQSVGPGEPRDVFLKVASGPSPEVKDFFVTIYVDRWLATPVQTWQVHLHSLQRVDVSCITGQRTRLALVLRGTQTVRRVQAFSSHPQELTTDPRGVFVLPPHGVQDLHVSVRPCRPGSRFAHLHLVDVDAHQLVASWLLCLSCRPPLISKAFEIKLPAGSGRGANKRITYTNPYPSRRAYRLHSDHPHLLQFKEDAFQVGGGETYTIGLRFVSRQRAGEEEILIYINDHEDKNEETFCVKVIYQ q29rs3_bovin IQCB1 protein protein bovin Bos taurus (Bovine) Bovine MKPTGTDPRILSLAAEVAKSPEQNVPVILLKLKEIINNTPLGSSELKKIKQDIYCYDLIQYCLLVLSQDCSRIQGGWTTVSQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGRRLQTCFINAAKGEEKDALLHFFEVVTDSLFWLLGGHVQLIQNVLKSDHFLRLLQTDSVQIGSMVMTLLQNILQINSGDLLRIEGKILHSILDEVVFKLLSTPSPVIRGTATKLLLLMAESHQEILILLRLSACYKGLRSLLNKQEPGTEFSQELRQLIGLLSPKACQEVKDQKQHKAACLIQAYWKGFQTRKRLKKLPSAVITLQRSFRSKRTKMLMKLSRQKEEEDHRLQLQIQRQRAMRLSREIRLNMLEIVHPGQVEKHNREIEEKSALIIQKHWKGYRERKNFRQQRPSLTEYKAAVILQRATLKFLAKCRKKKKLFAPWPGLRELTDARRIELKQQVDDYIRRHPGSQISDVTSRELHSQAQERLQCYFMGRALEERSQQHREALMAQISTNIEQLMKAPSLKEAEGKDPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEEAGDDIDIPKDELSVELGTLFIGGTKPP a0jn59_bovin INVS protein protein bovin Bos taurus (Bovine) Bovine MNRSENLFFAGSSLASQVHAAAINGDKGALHKLIIGNSALKDKEDQFGRTPLMYCVLADRLDCADTLLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHKSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRREAEQQKGRLSPDSCRPHAPLCLPRTQAEPHRQSRAPSKQPPCSDKAQGPERKACRRSPGRGSPSRAPQKEQQLSSDLQRTEPRKPNETAREHSKGRSACVHFSPSEGSDGNRRPGVCPAEKPRGETAGEQHCDKGKGSSKQPSHVKGAGPDAEGEEPSWAATSLPQQDSHWKASRRQDAAPKAMRASQKRRSQELRGGRRSPAGSSRPGSAKGEVVHPGQSPLHHRTPRNTVTQDKLAGGTSSDLPPSTEVLRSGVRKLGTSARSEDTRLPKETDPAPGPLPGQTVNIDLLPVELRLQIIQRERSRKELFRRKNKAAAIIQRAWRSYQLRKHLSHLLHVKQLGARDMDRWNRECLALILQVWRKELELKPPKTMAVSKTTKSPPKGSSGTKPTRHSVLKQIYGSQEGKVRQPTRSSKAHSVLGLNSVSNLQCIHLLKNSGKSQNFSYNLQSANPSRNKLKLRLPKEEDCARGARIASADFKFSD e1bjb4_bovin RPGRIP1L protein protein bovin Bos taurus (Bovine) Bovine MSGPTDETAGDLPVKDIGLNLFGMGGLQETSTTRTMKSRQAVSRISREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYEQVGGGPKRLGRDVEMEEMIERLQEKVHELERQNEVLKSRLISTKQQLQIQGHRHTPYSYVQSRVNTGRRRVNENAGLQECPRKGIKFQDTDVAETVQTMPTKYSNSLLKEARGEIRNLENVIESQRGQIEELERLAEILKTQLRRKENEIELSLLQLREHQATDQRSNIRDNVELIKLHKQLVEKSNALSVMEGKFIQLQEKQKTLRISHDALMANGDELNLQLKEQRLKCCSLEKQLRSMTFSERRIEELQDRISDLEKERELLKENYDKLYNSAFSAAHEEQWKLKEQQLKIQIAQLETALKSDLTDKTEILDRLKTERDQNEKISQENRQLQLQYLEQKQQLDELKNRMKFYNQESDINADELSEALLLIKAQKSQKNGDLSFLEKVDSKINKDLERSMKELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTQKMENLQQDYELKVEQYVHLLDIRAARIQKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPIVRGLHPEYNFTSQYLVHVNDLFLQYIQKNTVTLEVHQAYSTDYETIAACQLRFHEILEKSGRIFCTASLVGTKGDISNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEQMQWLSHQAPKTAQLSSTDSTDGNLNELHITIRCCNHLQSRASHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDDHMCFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYIGKVSVPLISLAHDRCISGIFELTDHEKHPAGTIHVILKWKFAYLPPSGCITTEDLGNFRHKEESEVVQRLLPTSSFSTIIAAPTPKPRRLTTKDKKVSFMDITPHQHYKETSTLPEDRKEISPEVEHIPEREIDMPTVSHIPKVPQESSVDKVKENTEKTQQGKDDDVSLLSEGQLAERSLTSSEDETEITEELEPEDEGDRSASDSDECIIPGPVSKNIKQPPEKIRIEIIALSLNDSRVTADDTIQRLFVECRFYSLPAEETPVSLPKPKSGQWVYYNYSYVIYMDKENNQAKRDILKAILLKQEMPNRSVRFTVVSDPPEDEQDLECEDIGIANVDLADVFREGRDIIEQNIDVLDARASGGGIGKLRVTVEALHALRSVYEQFRDDLEA ce290_bovin Centrosomal protein of 290 kDa CEP290 NPHP6 Nephrocystin-6 protein protein bovin Bos taurus (Bovine) Bovine ERQLRKENGKQKNELMAMEAEVGEKIGRLQRFKEMAVFKIAALQKVVDNSVSLSELELANRQYNELTAKYRDILQKDNMLVQRTNNLEHLECENVSLKEQMESINKELEITKEKLHTIEQAWEQETKLGNESNMDKAKKSVTNSEIVSISKKITMLEMKELNERQRAEHSQKMYEHVKTSLQQVEERNFELETKFAELTRINLEAQKVEQMLRDELADSVSKTVSDADRQHILELEKSEMELKVEVSKLKEISDIAKRQVEILNAQQQSREKEVESLRTQLLDYQAQSDEKALIAKLHQHVVSLQASEAAALGKVESVASKLQKVEAHTLRLEQKLDEKEQALFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMEEMKNSQQEHRSLKNKTLEMELKLKGLEDLISTLKDARGAQKVISWHTKIEELRLQELKLNRELVKDKEEIKYLNNIISEYENTISSLEEEIVQQNKFHEERQMAWDQREVELERQLDVFDRQQSEILREAQKFEEATGSMPDPSLPIPNQLEIALRKIKENIRIILETQATCRSLEEKLREKESALRLAEENILSRDKVINELRLRLPATAEQEKLLAEFSRKEVEPKSHHTLKLAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEELHTLHRKLELQADNSLSKFKETAWDLIKQSPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLVIKLKQVSQDLERQKEITELKIKEFENMKLRLQENHADEVKKIKAEVEDLRCLLVQSQKESQSLKSELQTQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISMTSQKEANLNVQQIVDRHTKELKSQIEDLNENILKLKEALKTSKNRENTLTDNLNDLTNELQNKQKAYGKVLREKDAVDQENNELKRQIKRLTSGLQGKPLIDNKQSLIEELQKKIKKLESQLERKVDEAEMKPMKEKSAREEVIRWEEGKKWQTKIEGIRNKLKEKEGEVYILTKQLTTLKDLFAKADKEKLTLQRKLKTTGLTVDQVMAARVLESEKELEELKKRNLDLENDISYMRSHQALPRDSVIEDLHLQNKYLQEKLHALEKQLSKDAYSRPSTSGIDSDDHYQREQELQRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVERKLGRVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEMENEKLKAELEKLKVHLGRQLSMHYESKAKGTEKIVAENERLRKELKKIEILKHVPEGDETEQGLQRELRVLRLANSQLEKEKEELIHRIEISKDQNGPDSTISDPDHLMEKIKDLETQLRTSDMEKQHLKEEIQKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKLKKLSEQFGVELTSPVAASEQFEDEQENPVNFPIY nphp4_human Nephrocystin-4 NPHP4 KIAA0673 Nephroretinin protein protein human Homo sapiens Human MNDWHRIFTQNVLVPPHPQRARQPWKESTAFQCVLKWLDGPVIRQGVLEVLSEVECHLRVSFFDVTYRHFFGRTWKTTVKPTKRPPSRIVFNEPLYFHTSLNHPHIVAVVEVVAEGKKRDGSLQTLSCGFGILRIFSNQPDSPISASQDKRLRLYHGTPRALLHPLLQDPAEQNRHMTLIENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPITGHLDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLDGGALEILERRLRVGVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGSQALVLRSRLRLPEMVGHPAFAVIFQLEYVFSSPAGVDGNAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGTSWPKTVYFTFQFYRFPPATTPRLQLVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQLRYMVGPGFLKPGERRCFARYLAVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQASHELEVVATEYEQDNMVVSGDMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCSTLPPSRSRVISNDGASRFSGGSLLTTGSSRRKHVVQAQKLADVDSELAAMLLTHARQGKGPQDVSRESDATRRRKLERMRSVRLQEAGGDLGRRGTSVLAQQSVRTQHLRDLQVIAAYRERTKAESIASLLSLAITTEHTLHATLGVAEFFEFVLKNPHNTQHTVTVEIDNPELSVIVDSQEWRDFKGAAGLHTPVEEDMFHLRGSLAPQLYLRPHETAHVPFKFQSFSAGQLAMVQASPGLSNEKGMDAVSPWKSSAVPTKHAKVLFRASGGKPIAVLCLTVELQPHVVDQVFRFYHPELSFLKKAIRLPPWHTFPGAPVGMLGEDPPVHVRCSDPNVICETQNVGPGEPRDIFLKVASGPSPEIKDFFVIIYSDRWLATPTQTWQVYLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRKVRAFTSHPQELKTDPKGVFVLPPRGVQDLHVGVRPLRAGSRFVHLNLVDVDCHQLVASWLVCLCCRQPLISKAFEIMLAAGEGKGVNKRITYTNPYPSRRTFHLHSDHPELLRFREDSFQVGGGETYTIGLQFAPSQRVGEEEILIYINDHEDKNEEAFCVKVIYQ rpgr_human X-linked retinitis pigmentosa GTPase regulator RPGR RP3 XLRP3 protein protein human Homo sapiens Human MREPEELMPDSGAVFTFGKSKFAENNPGKFWFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSARMRRRERERSPDSFSMRRTLPPIEGTLGLSACFLPNSVFPRCSERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVGNDTGQVGPQADTDGEGLQKEVYRHENNNGVDQLDAKEIEKESDGGHSQKESEAEEIDSEKETKLAEIAGMKDLREREKSTKKMSPFFGNLPDRGMNTESEENKDFVKKRESCKQDVIFDSERESVEKPDSYMEGASESQQGIADGFQQPEAIEFSSGEKEDDEVETDQNIRYGRKLIEQGNEKETKPIISKSMAKYDFKCDRLSEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEDHEFSKTEELKLEDVDEEINAENVESKKKTVGDDESVPTGYHSKTEGAERTNDDSSAETIEKKEKANLEERAICEYNENPKGYMLDDADSSSLEILENSETTPSKDMKKTKKIFLFKRVPSINQKIVKNNNEPLPEIKSIGDQIILKSDNKDADQNHMSQNHQNIPPTNTERRSKSCTIL nphp1_human Nephrocystin-1 Juvenile nephronophthisis 1 protein NPHP1 NPH1 protein protein human Homo sapiens Human MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEPYSEEEEGQESSEEGSEEDVEAVDETADGAEVKQRTDPHWSAVQKAISEAGIFCLVNHVSFCYLIVLMRNRMETVEDTNGSETGFRAWNVQSRGRIFLVSKPVLQINTVDVLTTMGAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDGNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV nphp4_mouse Nephrocystin-4 Nphp4 Nephroretinin protein protein mouse Mus musculus Mouse MGDWHRAFTQNTLVPPHPQRARQLGKESTAFQCILKWLDGPLIKQGILDMLSELECHLRVTLFDVTYKHFFGRTWKTTVKPTNQPSKQPPRITFNEPLYFHTTLSHPSIVAVVEVVTEGRKRDGTLQLLSCGFGILRIFGNKPESPTSAAQDKRLRLYHGTPRALLHPLLQDPIEQNKFMRLMENCSLQYTLKPHPPLEPAFHLLPENLLVSGFQQIPGLLPPHGDTGDALRKPRFQKPTTWHLDDLFFTLYPSLEKFEEELVQLLISDREGVGLLDSGTLEVLERRLHVCVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKISASSKNSSGNQALVLRSHLRLPEMVSHPAFAIVFQLEYVFNSPSGADGGASSPTSISSVACMHMVRWAVWNPDLEVGPGKVTLPLQGGVQQNPSRCLVYKVPSASMSSEEVKQVESGTIQFQFSLSSDGPTEHANGPRVGRRSSRKMPASPSGTPAPAARDLAATQDSPVGPGLSLSQLTASPLSPALQSSSKPPLQPPDSSQSPEGPQLQAESVLESRVSHLEADLSQPASLQGTPAVEHLQELPFTPLHAPIVVGAQTRSSRSQLSRAAMVLLQSSGFPEILDASQQPVEAVNPIDPVRFNPQKEESDCLRGNEIVLQFLAFSRAAQDCPGTPWPQTVYFTFQFYRFPPETTPRLQLVKLDGTGKSGSGSLSHILVPINKDGSFDAGSPGLQLRYMVDPGFLKPGEQRWFAHYLAAQTLQVDVWDGDSLLLIGSAGVQMKHLLRQGRPAVQVSHELEVVATEYEQEMMAVSGDVAGFGSVKPIGVHTVVKGRLHLTLANVGHACEPRARGSNLLPPSRSRVISNDGASFFSGGSLLIPGGPKRKRVVQAQRLADVDSELAAMLLTHTRAGQGPQAAGQEADAVHKRKLERMRLVRLQEAGGDSDSRRISLLAQHSVRAQHSRDLQVIDAYRERTKAESIAGVLSQAITTHHTLYATLGTAEFFEFALKNPHNTQHTVAIEIDSPELSIILDSQEWRYFKEATGLHTPLEEDMFHLRGSLAPQLYLRPRETAHIPLKFQSFSVGPLAPTQAPAEVITEKDAESGPLWKCSAMPTKHAKVLFRVETGQLIAVLCLTVEPQPHVVDQVFRFYHPELTFLKKAIRLPPWHTLPGAPVGMPGEDPPVHVRCSDPNVICEAQNVGPGEPRDVFLKVASGPSPEIKDFFVVIYADRWLAVPVQTWQVCLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRKVRAFTSHPQELKTDPAGVFVLPPHGVQDLHVGVRPRRAGSRFVHLNLVDIDYHQLVASWLVCLSCRQPLISKAFEITMAAGDEKGTNKRITYTNPYPSRRTYRLHSDRPELLRFKEDSFQVAGGETYTIGLRFLPSGSAGQEEILIYINDHEDKNEETFCVKVLYQ rpgr_mouse X-linked retinitis pigmentosa GTPase regulator Rpgr protein protein mouse Mus musculus Mouse MAESESLVPDTGAVFTFGKTKFAENIPSKFWFKNDIPICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLEDKSNVCIPHEVTVGKPISWISCGYYHSAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLRFAVQLIACGGCHMLVFATPRLGTIDEPKFEDVYEPYISTGSFSINDLSPRSSLNRSLSARLRRRERERPPCSASMVGTLPPLEGTSASTSAYFYPSSPPFHLSVNNYPEKSPSESMEPLDSDYFEDKMNKDTETENSSAVDSENFGETNDILNMTHMMTTSSNEKLLDFSPIQKQQNQDTFEKVMESTPCTENEDSYEYEEMSKIKEVTVYKQYLAKGIYMIRPAEILEAFSDEEVGNGLDQVEEPRVFTDGKGLQSKQVGKESDEEIVSEKKTEVMEVADVKKIRESEENSKSDSLFDDLPDKTMNSESEDNKDIAEERRSSEQNMTFDSETELVEEPDSYMECERHSEQDSAEELEQPKLVEYSSEEKDEKDEKDDDEVETENLWYDRNCTEQETENVFRATRFFPKFDLKHDHLSGIPEEQEGPEDSEGNVVVEQVVQAQKENLEFEGDRKEAKAEAPSDVITEKEAPQLSETVKPEEGEMDEEISILNVEDTVEEERKEGEKEIVEEGSIPETEGSETIDITDEKLDEVLKEEDSASLLQRALREYNENPKGHMYDRVKSSSSEILGGNDPTSKDIKKAKKISFFNRMSLTGQKLMQNTNDPLPEIKPIGDQIALQSDKKDANQNHMGQNLQDSTTPNMEGKSKSCTIL rpgr-nphp1-1 1940439 N/A 1940442 unspecified role unspecified role prey prey N/A 1940443 unspecified role unspecified role bait bait N/A 1940444 unspecified role unspecified role prey prey association association false false false 1A and 2A nphp1-rpgr-1 1940439 N/A 1940442 unspecified role unspecified role bait bait N/A 1940443 unspecified role unspecified role prey prey physical association physical association false false false 2B rpgr-invs-1 1940439 N/A 1940445 unspecified role unspecified role prey prey N/A 1940446 unspecified role unspecified role prey prey N/A 1940442 unspecified role unspecified role prey prey N/A 1940443 unspecified role unspecified role bait bait association association false false false 3C Detected in precipitate of NPHP4-depleted supernatant rpgr-cep290-3 1940439 N/A 1940447 unspecified role unspecified role prey prey N/A 1940448 unspecified role unspecified role prey prey N/A 1940443 unspecified role unspecified role bait bait N/A 1940444 unspecified role unspecified role prey prey association association false false false 4B Detected in precipitate of NPHP1-depleted supernatant nphp4-1 1940439 N/A 1940442 unspecified role unspecified role prey prey N/A 1940444 unspecified role unspecified role bait bait Detected in precipitate of RPGR-depleted supernatant physical association physical association false false false 5B Detected in precipitate of RPGR-depleted supernatant nphp1-nphp4-4 1940439 N/A 1940442 unspecified role unspecified role bait bait N/A 1940444 unspecified role unspecified role prey prey Detected in precipitate of RPGR-depleted supernatant physical association physical association false false false 5C Detected in precipitate of RPGR-depleted supernatant rpgr-nphp4-3 1940440 N/A 1940449 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false rabit-reticulocyte Oryctolagus cuniculus reticulocyte reticulocyte Reticulocytes N/A 1940450 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecoli Escherichia coli (strain K12) 1940483 1940480 physical association physical association false false false 1D and E rpgr-nphp4-4 1940440 N/A 1940451 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false rabit-reticulocyte Oryctolagus cuniculus reticulocyte reticulocyte Reticulocytes N/A 1940450 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) 1940489 1940487 physical association physical association false false false 2D and E rpgr-nphp4-2 1940441 N/A 1940452 unspecified role unspecified role prey prey N/A 1940453 unspecified role unspecified role bait bait physical association physical association false false false 1B