HPIDb Host Pathogen Interaction database http://www.agbase.msstate.edu/hpi/main.html http://www.agbase.msstate.edu/hpi/main.html lim-2014-1 Caveolin-1 mediates Salmonella invasion via the regulation of SopE-dependent Rac1 activation and actin reorganization. human-hdf Homo sapiens diploid fibroblasts cells human-hdf cells human diploid fibroblasts cells pull down pull down western blot western blot Immuno blot Immuno blot Lim J.S., Shin M., Kim H.J., Kim K.S., Choy H.E., Cho K.A. kacho@jnu.ac.kr J. Infect. Dis. (0022-1899) 2014 imex curation Lim J.S., Shin M., Kim H.J., Kim K.S., Choy H.E., Cho K.A., Lim J.S., Shin M., Kim H.J., Kim K.S., Choy H.E., Cho K.A. Only protein-protein interactions imex curation a0a0h3ngi8_salts Guanine nucleotide exchange factor sopE SL1344_2674 protein protein salts Salmonella typhimurium (strain SL1344) MTKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKYIQNTP rac1_human Ras-related C3 botulinum toxin substrate 1 RAC1 MIG5 p21-Rac1 Ras-like protein TC25 Cell migration-inducing gene 5 protein TC25 protein protein human Homo sapiens Human MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL pak1_human Serine/threonine-protein kinase PAK 1 PAK1 p21-activated kinase 1 p65-PAK Alpha-PAK protein protein human Homo sapiens Human MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH cav1_human Caveolin-1 CAV1 CAV protein protein human Homo sapiens Human MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI rac1-sope-pak1-cav1-1 1787787 N/A 1787788 unspecified role unspecified role prey prey N/A 1787789 unspecified role unspecified role prey prey RAC-1 was GTP bound N/A 1787790 unspecified role unspecified role bait bait N/A 1787791 unspecified role unspecified role prey prey association association false false false 4C and 5B pak1-cav1-1 1787787 N/A 1787789 unspecified role unspecified role prey prey RAC-1 was GTP bound N/A 1787791 unspecified role unspecified role bait bait physical association physical association false false false 4C, 5C and suppl. data 1 cav1-rac1-sope-1 1787787 N/A 1787788 unspecified role unspecified role prey prey N/A 1787791 unspecified role unspecified role bait bait N/A 1787789 unspecified role unspecified role prey prey RAC-1 was GTP bound association association false false false 4C pak1-cav1-rac1-1 1787787 N/A 1787789 unspecified role unspecified role prey prey RAC-1 was GTP bound N/A 1787790 unspecified role unspecified role bait bait N/A 1787791 unspecified role unspecified role prey prey association association false false false 4C, 5C, 5D and suppl. data 1 NSC23766, Rac1 inhibitor, inhibit Rac1-cav1 interaction pak1-cav1-sope-rac1-1 1787787 N/A 1787788 unspecified role unspecified role prey prey ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1787789 unspecified role unspecified role prey prey RAC-1 was GTP bound N/A 1787790 unspecified role unspecified role bait bait N/A 1787791 unspecified role unspecified role prey prey association association false false false suppl. data 1 cav1-sope-rac1-1 1787787 N/A 1787788 unspecified role unspecified role prey prey ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1787789 unspecified role unspecified role prey prey N/A 1787791 unspecified role unspecified role prey prey association association false false false suppl. data 1