IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ blasche-2014-1 The EHEC-host interactome reveals novel targets for the translocated intimin receptor yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence 2014-12-10: Peter Uetz, Virginia Commonwealth University, USA Each bait was fused to the GAL4-DBD (DNA binding domain of the GAL4 transcription factor) on both its N- and C-terminus. Two different prey screening libraries consisted of a single pool of over 10,000 individual human protein-coding ORFs that were either fused C- or N-terminally to the AD (activation domain) of GAL4. The N- and C-terminally-tagged effector bait constructs were then screened individually against both ORFeome libraries to increase the detection sensitivity as well as against a cDNA prey library (Human Universal). These screens resulted in 1,025 positive yeast colonies from which 328 unique EHEC bait-human prey pairs were identified. 207 pairs with prey sequences that were not located in the protein coding region of genes or interactions including prey proteins known to interact non-selectively with many different bait proteins were removed. In the final dataset, all PPIs that were isolated multiple times, as well as those that were independently reproduced were included. One additional interaction EspG (ECs4590) with ‘‘Hs.658052’’ (UGID:2727370) was recorded but the identitiy of the human protein could not be traced. peter@uetz.us Only protein-protein interactions imex curation Blasche S., Arens S., Ceol A., Siszler G., Schmidt M.A., Häuser R., Schwarz F., Wuchty S., Aloy P., Uetz P., Stradal T., Koegl M. Sci Rep 2014 blasche-2014-3 The EHEC-host interactome reveals novel targets for the translocated intimin receptor yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined 2014-12-10: Peter Uetz, Virginia Commonwealth University, USA peter@uetz.us Only protein-protein interactions imex curation Blasche S., Arens S., Ceol A., Siszler G., Schmidt M.A., Häuser R., Schwarz F., Wuchty S., Aloy P., Uetz P., Stradal T., Koegl M. Sci Rep 2014 blasche-2014-2 The EHEC-host interactome reveals novel targets for the translocated intimin receptor human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. lumier luminescence based mammalian interactome mapping lumier tag luciferase tag visualisation by luciferase assay tag luciferase 2014-12-10: Peter Uetz, Virginia Commonwealth University, USA peter@uetz.us Only protein-protein interactions imex curation Blasche S., Arens S., Ceol A., Siszler G., Schmidt M.A., Häuser R., Schwarz F., Wuchty S., Aloy P., Uetz P., Stradal T., Koegl M. Sci Rep 2014 q8xc86_eco57 E5F08_27370 espB ECs_4554 protein protein eco57 Escherichia coli O157:H7 MNTIDNTQVTMVNSASESTTGASSAVAASALSIDSSLLTDGKVDICKLMLEIQKLLGKMVTLLQDYQQKQLAQSYQIQQAVFESQNKAIEEKKAAATAALVGGIISSALGILGSFAAMNNAAKGAGEIAEKASSASSKAAGAASEVANKALVKATESVADVAEEASSAMQKAMATTTKAASRASGVADDVAKASDFAEDLADAAEKTSRINKLLNSVDKLTNTTAFVAVTSLAEGTKTLPTTISESVKSTHEVNEQRAKSLENFQQGNLELYKQDVRRTQDDITTRLRDITSAVRDLLEVQNRMGQSGRLAG hoil1_human RanBP-type and C3HC4-type zinc finger-containing protein 1 RBCK1 C20orf18 RNF54 UBCE7IP3 XAP3 XAP4 Ubiquitin-conjugating enzyme 7-interacting protein 3 Hepatitis B virus X-associated protein 4 HBV-associated factor 4 RING finger protein 54 Heme-oxidized IRP2 ubiquitin ligase 1 RING-type E3 ubiquitin transferase HOIL-1 protein protein human Homo sapiens Human MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH stk16_human Serine/threonine-protein kinase 16 STK16 MPSK1 PKL12 TSF1 Protein kinase PKL12 Myristoylated and palmitoylated serine/threonine-protein kinase TGF-beta-stimulated factor 1 hPSK Tyrosine-protein kinase STK16 protein protein human Homo sapiens Human MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQHTTQI md2l2_human Mitotic spindle assembly checkpoint protein MAD2B MAD2L2 MAD2B REV7 Mitotic arrest deficient 2-like protein 2 REV7 homolog protein protein human Homo sapiens Human MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGS q7db85_eco57 E5F08_27350 espF ECs_4550 protein protein eco57 Escherichia coli O157:H7 MLNGISNAASTLGRQLVGIASRVSSAGGTGFSVAPQAVRLTPVKVHSPFSPGSSNVNARTIFNVSSQVTSFTPSRPAPPPPTSGQASGASRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTSGQASGASRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTSGQASGASRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTGPSGLPPLAQALKDHLAAYEQSKKG snx33_human Sorting nexin-33 SNX33 SH3PX3 SH3PXD3C SNX30 SH3 and PX domain-containing protein 3 protein protein human Homo sapiens Human MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDWDDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGRNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL snx9_human Sorting nexin-9 SNX9 SH3PX1 SH3PXD3A SH3 and PX domain-containing protein 1 SH3 and PX domain-containing protein 3A protein protein human Homo sapiens Human MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEILPSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM q7db50_eco57 espG ECs_4590 E5F08_27545 protein protein eco57 Escherichia coli O157:H7 MINGLNNDSASLVLDAAMKVNSGFKKSWDEMSCAEKLFKVLSFGLWNPTYSRSERQSFQELLTVLEPVYPLPNELGRVSARFSDGSSLRISVTNSELVEAEIRTANNEKITVLLESNEQNRLLQSLPIDRHMPYIQVHRALSEMDLTDTTSMRNLLGFTSKLSTTLIPHNAQTDPLSGPTPFSSIFMDTCRGLGNAKLSLNGVDIPANAQKLLRDALGLKDTHSSPTRNVIDHGISRHDAEQIARESSGSDKQKAEVVEFLCHPEAATAICSAFYQSFNVPALTLTHERISKASEYNAERSLDTPNACINISISQSSDGNIYVTSHTGVLIMAPEDRPNEMGMLTNRTSYEVPQGVKCIIDEMVSALQPRYAASETYLQNT nmi_human N-myc-interactor NMI N-myc and STAT interactor protein protein human Homo sapiens Human MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQIKEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVSMSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTEIHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQPHIAYFEE cenph_human Centromere protein H Interphase centromere complex protein 35 ICEN35 CENPH protein protein human Homo sapiens Human MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQLEKNVDMM q8xb62_eco57 E5F08_17465 espJ ECs_2714 protein protein eco57 Escherichia coli O157:H7 MSIIKNCLSLINNALNIQKTSYSLTKMEQAGKLLNRKITPENTPPMLLSYRNADLTQEKNITERVLSIFKIKRDFVAVRIQNNQFTDLKNKKIQGHQNTVASVMDWYNPQKNALGITMGTPRKSADIAKEEHRNALNFMIMEKNTFHEKILNSNDNLQKSYSKTEDSSWVAASVGSLLDKGAKVYPDTSCSLRLGEPFIFTLPESVRVDVDIYPLKK ift20_human Intraflagellar transport protein 20 homolog IFT20 protein protein human Homo sapiens Human MAKDILGEAGLHFDELNKLRVLDPEVTQQTIELKEECKDFVDKIGQFQKIVGGLIELVDQLAKEAENEKMKAIGARNLLKSIAKQREAQQQQLQALIAEKKMQLERYRVEYEALCKVEAEQNEFIDQFIFQK mr1l1_human MORF4 family-associated protein 1-like 1 PP784 MRFAP1L1 protein protein human Homo sapiens Human MRPLDIDEVEAPEEVEVLEPEEDFEQFLLPVINEMREDIASLIREHGRAYLRTRSKLWEMDNMLIQIKTQVEASEESALNHVQHPSGEADERVSELCEKAEEKAKEIAKMAEMLVELVWRIERSESS This sequence has been withdrawn from Uniprot. 6C914B0B4BEECAE5 ric8a_human Synembryn-A Protein Ric-8A RIC8A protein protein human Homo sapiens Human MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLPPSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESADMDVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELKGVRLLTDTLELTLGVTPEGNPPPTLLPSQETERAMEILKVLFNITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTEEFHGHAVNLLGNLPLKCLDVLLTLEPHGDSTEFMGVNMDVIRALLIFLEKRLHKTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAMCETMEQQLSSDPDSDPD a0a0h3jfn8_eco57 E5F08_11480 espO1-1 ECs_1567 protein protein eco57 Escherichia coli O157:H7 MPFSIKNRFSSSQVHYPEISGPIKDKPASKNCILTSTTCNVDSYTVYQKKACSFDMRPPGAGERTPKLKLSVTEMTWLSKTIETEIHNTKE fem1b_human Protein fem-1 homolog B FEM1B KIAA0396 F1AA FEM1-beta Fem-1-like death receptor-binding protein alpha Fem-1-like in apoptotic pathway protein alpha protein protein human Homo sapiens Human MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIKLWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH can3_human Calpain-3 CANP3 CANPL3 Calcium-activated neutral proteinase 3 Calpain L3 Calpain p94 Muscle-specific calcium-activated neutral protease 3 NCL1 New calpain 1 CAPN3 protein protein human Homo sapiens Human MPTVISASVAPRTAAEPRSPGPVPHPAQSKATEAGGGNPSGIYSAIISRNFPIIGVKEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADALQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA q8xa11_eco57 E5F08_03670 espY1 ECs_0061 protein protein eco57 Escherichia coli O157:H7 MKVSVPGMPATLLNMSNNDIYKMVSGDKMDMKMNIFQRLWETLRHLFWSDKQTEAYKLLFNFVNKKAGNINASKYFTGAVNENEKEKFIHSLELFNELKTCAKNPDEMVAKGNMSWVAQTFGDIELSVTFFIENKEICTQTLQLHKGPGNLGVDLREAYLPGVDMRDCYLGLKTMKGHNKVLYLEPGWNANLDGATLDGATLDGATVDGATHLYDEVIIINKITPKKIDTEEVATKQSTAEQITDNAIIE c2ail_human CDKN2AIP N-terminal-like protein CDKN2AIPNL CDKN2A-interacting protein N-terminal-like protein protein protein human Homo sapiens Human MVGGEAAAAVEELVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGSGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTTRSELMKKHQS clk1_human Dual specificity protein kinase CLK1 CDC-like kinase 1 CLK1 CLK protein protein human Homo sapiens Human MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIHHSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKSI djc14_human DnaJ homolog subfamily C member 14 DNAJC14 DRIP78 HDJ3 DnaJ protein homolog 3 Dopamine receptor-interacting protein of 78 kDa Human DnaJ protein 3 protein protein human Homo sapiens Human MAQKHPGERGLYGAHHSGGASLRTLGPSVDPEIPSFSGLRDSAGTAPNGTRCLTEHSGPKHTQHPNPAHWLDPSHGPPGGPGPPRDAEDPDQSETSSEEESGVDQELSKENETGNQKDGNSFLSIPSACNCQGTPGIPEGPYSEGGNGSSSNFCHHCTSPALGEDELEEEYDDEESLKFPSDFSRVSSGKKPPSRRQRHRFPTKEDTREGGRRDPRSPGRHRLGRKRSQADKRKGLGLWGAEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRQLKSSDLDLFRVWMGVWTGRLGGWAQVMFQFLSQGFYCGVGLFTRFLKLLGALLLLALALFLGFLQLGWRFLVGLGDRLGWRDKATWLFSWLDSPALQRCLTLLRDSRPWQRLVRIVQWGWLELPWVKQNINRQGNAPVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNAEKRKEYEMKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRIPGTRGRQRATPDAPPADLQDFLSRIFQVPPGQMPNGNFFAAPQPAPGAAAASKPNSTVPKGEAKPKRRKKVRRPFQR pcid2_human PCI domain-containing protein 2 CSN12-like protein PCID2 HT004 protein protein human Homo sapiens Human MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC pihd1_human PIH1 domain-containing protein 1 PIH1D1 NOP17 Nucleolar protein 17 homolog protein protein human Homo sapiens Human MANPKLLGMGLSEAEAIGADSARFEELLLQASKELQQAQTTRPESTQIQPQPGFCIKTNSSEGKVFINICHSPSIPPPADVTEEELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSISQQNIRSEQRPRIQELGDLYTPAPGRAESGPEKPHLNLWLEAPDLLLAEVDLPKLDGALGLSLEIGENRLVMGGPQQLYHLDAYIPLQINSHESKAAFHRKRKQLMVAMPLLPVPS prs4_human 26S proteasome regulatory subunit 4 PSMC1 26S proteasome AAA-ATPase subunit RPT2 Proteasome 26S subunit ATPase 1 protein protein human Homo sapiens Human MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL znhi1_human Zinc finger HIT domain-containing protein 1 Cyclin-G1-binding protein 1 Zinc finger protein subfamily 4A member 1 p18 Hamlet ZNHIT1 CGBP1 ZNFN4A1 protein protein human Homo sapiens Human MVEKKTSVRSQDPGQRRVLDRAARQRRINRQLEALENDNFQDDPHAGLPQLGKRLPQFDDDADTGKKKKKTRGDHFKLRFRKNFQALLEEQNLSVAEGPNYLTACAGPPSRPQRPFCAVCGFPSPYTCVSCGARYCTVRCLGTHQETRCLKWTV q7db76_eco57 E5F08_27410 map ECs_4562 protein protein eco57 Escherichia coli O157:H7 MFSPMTMAGRSLVQATAQTLKPAVTRAAMQAGTGATGMRFMPVQSNFVINHGKLTNQLLQAVAKQTRNGDTQQWFQQEQTTYISRTVNRTLDDYCRSNNSVISKETKGHIFRAVENALQQPLDMNGAQSSIGHFLQSNKYFNQKVDEQCGKRVDPITRFNTQTKMIEQVSQEIFERNFSGFKVSEIKAITQNAILEHVQDTRL rhpn1_human Rhophilin-1 KIAA1929 GTP-Rho-binding protein 1 RHPN1 protein protein human Homo sapiens Human MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP nhrf2_human Na(+)/H(+) exchange regulatory cofactor NHE-RF2 SLC9A3R2 NHERF2 Tyrosine kinase activator protein 1 SRY-interacting protein 1 Solute carrier family 9 isoform A3 regulatory factor 2 NHE3 kinase A regulatory protein E3KARP Sodium-hydrogen exchanger regulatory factor 2 protein protein human Homo sapiens Human MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF q8xaj5_eco57 E5F08_14940 nleA espI ECs_1812 protein protein eco57 Escherichia coli O157:H7 MNIQPTIQSGITSQNNQHHQTEQIPSTQIPQSELPLGCQAGFVVNIPDDIQQHAPECGETTALLSLIKDKGLLSGLDEYIAPHLEEGSIGKKTLDMFGLFNVTQMALEIPSSVSGISGKYGVQLNIVKPDIHPTSGNYFLQIFPLHDEIGFNFKDLPGPLKNALSNSNISTTAVSTIASTGTSATTSTVTTEPKDPIPWFGLTAQVVRNHGVELPIVKTENGWKLVGETPLTPDGPKANYTEEWVIRPGEADFKYGASPLQATLGLEFGAHFKWDLDNPNTKYAVLTNAAANALGALGGFAVSRFASTDPMLSPHIGAMVGQAAGHAIQYNTPGLKPDTILWWAGATLGAADLNKAEFEVARFTDYPRIWWHAREGAIFPNKADIEHATGADIRAMEEGIPVGQRHPNPEDVVIDIESNGLPHHNPSNHVDIFDIIQETRV dscr4_human Down syndrome critical region protein 4 DSCR4 DCRB DSCRB Down syndrome critical region protein B protein protein human Homo sapiens Human MSLIILTRDDEPRIFTPDSDAASPALHSTSPLPDPASASPLHREEKILPKVCNIVSCLSFSLPASPTDSGLASPTIITREGQQFWAKCLIWKYQLYLHGLHKKSDGRRDKQISASPST frmd3_human FERM domain-containing protein 3 Band 4.1-like protein 4O EPB41L4O Ovary type protein 4.1 FRMD3 protein protein human Homo sapiens Human MFASCHCVPRGRRTMKMIHFRSSSVKSLSQEMRCTIRLLDDSEISCHIQRETKGQFLIDHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKTHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYISEFEIFPKQSQKLERKIVEIHKNELRGQSPPVAEFNLLLKAHTLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLIKWPDVCKLKFEGKTFYVIGTQKEKKAMLAFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTVSSSKIFFKGSRFRYSGKVAKEVVEASSKIQREPPEVHRANITQSRSSHSLNKQLIINMEPLQPLLPSPSEQEEELPLGEGVPLPKEENISAPLISSSPVKAAREYEDPPSEEEDKIKEEPLTISELVYNPSASLLPTPVDDDEIDMLFDCPSRLELEREDTDSFEDLEADENAFLIAEEEELKEARRALSWSYDILTGHIRVNPLVKSFSRLLVVGLGLLLFVFPLLLLLLESGIDLSFLCEIRQTPEFEQFHYEYYCPLKEWVAGKVHLILYMLGCS penk_human Proenkephalin-A PENK protein protein human Homo sapiens Human MARFLTLCTWLLLLGPGLLATVRAECSQDCATCSYRLVRPADINFLACVMECEGKLPSLKIWETCKELLQLSKPELPQDGTSTLRENSKPEESHLLAKRYGGFMKRYGGFMKKMDELYPMEPEEEANGSEILAKRYGGFMKKDAEEDDSLANSSDLLKELLETGDNRERSHHQDGSDNEEEVSKRYGGFMRGLKRSPQLEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAEALPSDEEGESYSKEVPEMEKRYGGFMRF tp4a1_human Protein tyrosine phosphatase type IVA 1 PTP4A1 PRL1 PTPCAAX1 PTP(CAAXI) Protein-tyrosine phosphatase 4a1 Protein-tyrosine phosphatase of regenerating liver 1 protein protein human Homo sapiens Human MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ drg2_human Developmentally-regulated GTP-binding protein 2 DRG2 Translation factor GTPase DRG2 protein protein human Homo sapiens Human MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK nleb1_eco57 Protein-arginine N-acetylglucosaminyltransferase NleB1 nleB1 Non-LEE-encoded type III effector B1 ECs_3857 protein protein eco57 Escherichia coli O157:H7 MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYPLEPIDEKTPILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAAKIENERIIGVLVDGNFTYEQKKEFLSLENEYQNIKIIYRADVDFSMYDKKLSDIYLENIHKQESYPASERDNYLLGLLREELKNIPEGKDSLIESYAEKREHTWFDFFRNLAMLKAGSLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIAVHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLHDYNAFCDFIEFKHENIIPNTSMYTCSSW lrc18_human Leucine-rich repeat-containing protein 18 LRRC18 UNQ9338/PRO34010 protein protein human Homo sapiens Human MVKGEKGPKGKKITLKVARNCIKITFDGKKRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFPKPGESEIFIDSIRRLENLYVVEEKDLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNLISPNSMAKDSWEDWRIRLTSS rpab1_human DNA-directed RNA polymerases I, II, and III subunit RPABC1 POLR2E DNA-directed RNA polymerase II subunit E RPB5 homolog DNA-directed RNA polymerase II 23 kDa polypeptide XAP4 protein protein human Homo sapiens Human MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ q8x834_eco57 E5F08_07745 nleC ECs_0847 protein protein eco57 Escherichia coli O157:H7 MICRVLDINMKIPSLQSNFNFSAPAGYSAPIAPNRAENAYADYVLDIGKRIPLSAADLSNVYESVIRAVHDSRSRLIDQHTVDMIGNTVLDALSRSQTFRDAVSYGIHNEKVHIGCIKYRNEYELNEESSVKIDDIQSLTCNELYEYDVGQEPIFPICEAGENDNEEPYVSFSVAPDTDSYEMPSWQEGLIHEIIHHVTGSSDPSGDSNIELGPTEILARRVAQELGWSVPDFKGYAEPEREAHLRLRNLNALRQAAMRHEENERAFFERLGTISDRYEASPDFTEYSAVSNIGYGFIQQHDFPGLAINDNLQDANQIQLYHGAPYIFTFGDVDKHNQQ ch071_human Putative uncharacterized protein encoded by LINC00588 LINC00588 C8orf71 protein protein human Homo sapiens Human MATFHRAHATSSVKPRARRHQEPNSGDWPGSYRAGTRCSAIGFRLLHSPQHWRPRSLGAGQGREDPSWEGGALGDLKALWDQPCQPPPWVQLQLSSAYGARQQRWQLSTLPEPPAARTPGQMPQQRLIRAAGPSAAGGGNQWLSPM ctsl2_human CTD small phosphatase-like protein 2 HSPC058 HSPC129 CTDSPL2 protein protein human Homo sapiens Human MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD met2a_human tRNA N(3)-methylcytidine methyltransferase METTL2A METTL2A METTL2 Methyltransferase-like protein 2A HSPC266 protein protein human Homo sapiens Human MAGSYPEGAPAVLADKRQQFGSRFLRDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENKSEVPECRNNEDGPGLIMEEQHKCSSKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLSAIVPDKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS mint Probable methyltransferase homomint a0a0h3jgr6_eco57 E5F08_07770 nleD ECs_0850 protein protein eco57 Escherichia coli O157:H7 MRPTSLNLVLHQSSRSSSMSDTDIESLVKASSVQWIKNNPQLRFQGTDHNIYQQIEAALDKIGSTETGRVLLNAIESISRLKSETVVIHLNSSRLGVMAHRDIDAENHRGTGSDFHCNLNAVEYPCGEGISVVDFHATIVFHELLHVFHNLNGERLKVESSRAESQKYSPLLLEEARTVGLGAFSEEVLSENKFHEEIGMPRRTSYPHDSALIHDDNTVSLGFQQVRLHPLL casp9_human Caspase-9 ICE-like apoptotic protease 6 Apoptotic protease Mch-6 Apoptotic protease-activating factor 3 CASP9 MCH6 protein protein human Homo sapiens Human MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS nlef_eco57 Effector protein NleF nleF Non-LEE-encoded type III effector F Z6020.1 ECs1815 protein protein eco57 Escherichia coli O157:H7 MLPTSGSSANLYSWMYVSGRGNPSTPESVSELNHNHFLSPELQDKLDVMVSIYSCARNNNELEEIFQELSAFVSGLMDKRNSVFEVRNENTDEVVGALRAGMTIEDRDSYIRDLFFLHSLKVKIEESRQGKEDSKCKVYNLLCPHHSSELYGDLRAMKCLVEGCSDDFNPFDIIRVPDLTYNKGSLQCG dyr_human Dihydrofolate reductase DHFR protein protein human Homo sapiens Human MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND eri3_human ERI1 exoribonuclease 3 ERI3 PINT1 PRNPIP PRNPIP1 Prion interactor 1 Prion protein-interacting protein protein protein human Homo sapiens Human MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTEPSASPAAGLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF lmo4_human LIM domain transcription factor LMO4 Breast tumor autoantigen LIM domain only protein 4 LMO4 protein protein human Homo sapiens Human MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC C8AC295144AD7787 trnt1_human CCA tRNA nucleotidyltransferase 1, mitochondrial TRNT1 Mitochondrial tRNA nucleotidyl transferase, CCA-adding mt CCA-adding enzyme mt tRNA CCA-diphosphorylase mt tRNA CCA-pyrophosphorylase mt tRNA adenylyltransferase CGI-47 protein protein human Homo sapiens Human MLRCLYHWHRPVLNRRWSRLCLPKQYLFTMKLQSPEFQSLFTEGLKSLTELFVKENHELRIAGGAVRDLLNGVKPQDIDFATTATPTQMKEMFQSAGIRMINNRGEKHGTITARLHEENFEITTLRIDVTTDGRHAEVEFTTDWQKDAERRDLTINSMFLGFDGTLFDYFNGYEDLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDKPGDHDPETLEAIAENAKGLAGISGERIWVELKKILVGNHVNHLIHLIYDLDVAPYIGLPANASLEEFDKVSKNVDGFSPKPVTLLASLFKVQDDVTKLDLRLKIAKEEKNLGLFIVKNRKDLIKATDSSDPLKPYQDFIIDSREPDATTRVCELLKYQGEHCLLKEMQQWSIPPFPVSGHDIRKVGISSGKEIGALLQQLREQWKKSGYQMEKDELLSYIKKT q8xal6_eco57 E5F08_14920 nleH1_2 ECs_1814 protein protein eco57 Escherichia coli O157:H7 MLSPSSINLGCSWNSLTRNLTSPDNRVLSSVRDAAVHSDSGTQVTVGNRTYRVVVTDNKFCVTRESHSGCFTNLLHRLGWPKGEISRKIEAMLNTSPVSTTIERGSVHSNRPDLPPVDYAQPELPPADYTQSELPRVSNNKSPVPGNVIGKGGNAVVYEDMEDTTKVLKMFTISQSHEEVTSEVRCFNQYYGSGSAEKIYNDNGNVIGIRMNKINGESLLDIPSLPAQAEQAIYDMFDRLEKKGILFVDTTETNVLYDRMRNEFNPIDISSYNVSDISWSEHQVMQSYHGGKLDLISVVLSKI ufc1_human Ubiquitin-fold modifier-conjugating enzyme 1 UFC1 CGI-126 HSPC155 protein protein human Homo sapiens Human MADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIQHKEKCNQ esfu2_eco57 Secreted effector protein EspF(U) espF(U) tccP EspF-like protein encoded on prophage U Tir-cytoskeleton coupling protein TccP ECs2715 protein protein eco57 Escherichia coli O157:H7 MINNVSSLFPTVNRNITAVYKKSSFSVSPQKITLNPVKISSPFSPSSSSISATTLFRAPNAHSASFHRQSTAESSLHQQLPNVRQRLIQHLAEHGIKPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPLPVQNEQSRPLPDVAQRLVQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS This sequence has been withdrawn from Uniprot. zn626_human Zinc finger protein 626 ZNF626 protein protein human Homo sapiens Human MGPLQFRDVAIEFSLEEWHCLDTAQRNLYRNVMLENYSNLVFLGITVSKPDLITCLEQGRKPLTMKRNEMIAKPSVMCSHFAQDLWPEQSMKDSFQKVVLRRYEKCEHDNLQLKKGCISVDECKVHKEGYNELNQCLTTTPRKICQCDKYVKVLHQFPNSNGQKRGHTGKKPFKYIECGKAFKQFSTLTTHKKIHTGGKPYKCEECGKAFNHSCSLTRHKKIHTGEKPYKCEECGKAFKHSSTLTTHKRNHTGEKPYKCDKCGKAFMSSSTLSKHEIIHTEKKPYKCEECGKAFNRSSTLTTHKIIHTGEKPYKCEECDKAFKYSYTLTTHKRIHTEDKPYKCEECGKAFKYSSTLTTHKRIHTGEKPYKCEECGKAFKRSSDLTTHKIIHTGEKPYKCEECGKAFKYSSNLTTHKKIHTGERPYKCEECGKAFNQSSILTTHRRIHTGEKFYKCEECGKAFKCSSNLTTHKKIHTGERPYKCEECGKAFNQSSILTTHERIILERNSTNVKNVAKPSSGPHTLLHIR arrb1_human Beta-arrestin-1 Arrestin beta-1 ARRB1 ARR1 Non-visual arrestin-2 protein protein human Homo sapiens Human MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR tir_eco57 Translocated intimin receptor Tir tir espE Secreted effector protein Tir Z5112 ECs4561 protein protein eco57 Escherichia coli O157:H7 MPIGNLGHNPNVNNSIPPAPPLPSQTDGAGGRGQLINSTGPLGSRALFTPVRNSMADSGDNRASDVPGLPVNPMRLAASEITLNDGFEVLHDHGPLDTLNRQIGSSVFRVETQEDGKHIAVGQRNGVETSVVLSDQEYARLQSIDPEGKDKFVFTGGRGGAGHAMVTVASDITEARQRILELLEPKGTGESKGAGESKGVGELRESNSGAENTTETQTSTSTSSLRSDPKLWLALGTVATGLIGLAATGIVQALALTPEPDSPTTTDPDAAASATETATRDQLTKEAFQNPDNQKVNIDELGNAIPSGVLKDDVVANIEEQAKAAGEEAKQQAIENNAQAQKKYDEQQAKRQEELKVSSGAGYGLSGALILGGGIGVAVTAALHRKNQPVEQTTTTTTTTTTTSARTVENKPANNTPAQGNVDTPGSEDTMESRRSSMASTSSTFFDTSSIGTVQNPYADVKTSLHDSQVPTSNSNTSVQNMGNTDSVVYSTIQHPPRDTTDNGARLLGNPSAGIQSTYARLALSGGLRHDMGGLTGGSNSAVNTSNNPPAPGSHRFV bi2l1_human Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 BAIAP2L1 IRTKS Insulin receptor tyrosine kinase substrate protein protein human Homo sapiens Human MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR hpcl1_human Hippocalcin-like protein 1 Visinin-like protein 3 Calcium-binding protein BDR-1 HLP2 HPCAL1 BDR1 protein protein human Homo sapiens Human MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF hpcl4_human Hippocalcin-like protein 4 HPCAL4 protein protein human Homo sapiens Human MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK ncald_human Neurocalcin-delta NCALD protein protein human Homo sapiens Human MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF pde6d_human Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Protein p17 PDE6D PDED protein protein human Homo sapiens Human MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV baip2_human Brain-specific angiogenesis inhibitor 1-associated protein 2 Insulin receptor substrate protein of 53 kDa Insulin receptor substrate p53/p58 Fas ligand-associated factor 3 BAIAP2 protein protein human Homo sapiens Human MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPAQTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRCDLSAQGPEGREHGDGSARTLAGR hmgn2_human Non-histone chromosomal protein HMG-17 HMGN2 HMG17 High mobility group nucleosome-binding domain-containing protein 2 protein protein human Homo sapiens Human MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKEGNNPAENGDAKTDQAQKAEGAGDAK tir_eco27 Translocated intimin receptor Tir tir Secreted effector protein Tir espE E2348C_3941 protein protein eco27 Escherichia coli O127:H6 (strain E2348/69 / EPEC) MPIGNLGNNVNGNHLIPPAPPLPSQTDGAARGGTGHLISSTGALGSRSLFSPLRNSMADSVDSRDIPGLPTNPSRLAAATSETCLLGGFEVLHDKGPLDILNTQIGPSAFRVEVQADGTHAAIGEKNGLEVSVTLSPQEWSSLQSIDTEGKNRFVFTGGRGGSGHPMVTVASDIAEARTKILAKLDPDNHGGRQPKDVDTRSVGVGSASGIDDGVVSETHTSTTNSSVRSDPKFWVSVGAIAAGLAGLAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFKNPENQKVNIDANGNAIPSGELKDDIVEQIAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEELQLSSGIGYGLSSALIVAGGIGAGVTTALHRRNQPAEQTTTTTTHTVVQQQTGGNTPAQGGTDATRAEDASLNRRDSQGSVASTHWSDSSSEVVNPYAEVGGARNSLSAHQPEEHIYDEVAADPGYSVIQNFSGSGPVTGRLIGTPGQGIQSTYALLANSGGLRLGMGGLTSGGESAVSSVNAAPTPGPVRFV espb-rbck1 1765556 n/a 1765559 unspecified role unspecified role bait bait n/a 1765560 unspecified role unspecified role prey prey physical association physical association false false false Table 1 espb-stk16 1765556 n/a 1765561 unspecified role unspecified role prey prey n/a 1765559 unspecified role unspecified role bait bait physical association physical association false false false Table 1 espf-mad2l2 1765556 n/a 1765562 unspecified role unspecified role prey prey n/a 1765563 unspecified role unspecified role bait bait physical association physical association false false false Table 1 espf-snx33 1765556 n/a 1765564 unspecified role unspecified role prey prey n/a 1765563 unspecified role unspecified role bait bait physical association physical association false false false Table 1 espf-snx9-3 1765556 n/a 1765563 unspecified role unspecified role bait bait n/a 1765565 unspecified role unspecified role prey prey physical association physical association false false false Table 1 espg-nmi 1765556 n/a 1765566 unspecified role unspecified role bait bait n/a 1765567 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xb62-cenph 1765556 n/a 1765568 unspecified role unspecified role prey prey n/a 1765569 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xb62-ift20 1765556 n/a 1765569 unspecified role unspecified role bait bait n/a 1765570 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xb62-mrfap1l1 1765556 n/a 1765571 unspecified role unspecified role prey prey n/a 1765569 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xb62-ric8a 1765556 n/a 1765572 unspecified role unspecified role prey prey n/a 1765569 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8x3g1-fem1b 1765556 n/a 1765573 unspecified role unspecified role bait bait n/a 1765574 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xa11-capn3 1765556 n/a 1765575 unspecified role unspecified role prey prey n/a 1765576 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xa11-cdkn2aipnl 1765556 n/a 1765577 unspecified role unspecified role prey prey n/a 1765576 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xa11-clk1 1765556 n/a 1765578 unspecified role unspecified role prey prey n/a 1765576 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xa11-dnajc14 1765556 n/a 1765576 unspecified role unspecified role bait bait n/a 1765579 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xa11-pcid2 1765556 n/a 1765576 unspecified role unspecified role bait bait n/a 1765580 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xa11-pih1d1 1765556 n/a 1765576 unspecified role unspecified role bait bait n/a 1765581 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xa11-psmc1 1765556 n/a 1765576 unspecified role unspecified role bait bait n/a 1765582 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xa11-znhit1 1765556 n/a 1765583 unspecified role unspecified role prey prey n/a 1765576 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q7db76-rhpn1 1765556 n/a 1765584 unspecified role unspecified role bait bait n/a 1765585 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q7db76-slc9a3r2 1765556 n/a 1765586 unspecified role unspecified role prey prey n/a 1765584 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xaj5-dscr4 1765556 n/a 1765587 unspecified role unspecified role bait bait n/a 1765588 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xaj5-frmd3 1765556 n/a 1765589 unspecified role unspecified role prey prey n/a 1765587 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xaj5-penk 1765556 n/a 1765587 unspecified role unspecified role bait bait n/a 1765590 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xaj5-ptp4a1 1765556 n/a 1765587 unspecified role unspecified role bait bait n/a 1765591 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xbx8-drg2 1765556 n/a 1765592 unspecified role unspecified role prey prey n/a 1765593 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xbx8-lrrc18 1765556 n/a 1765594 unspecified role unspecified role prey prey n/a 1765593 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xbx8-polr2e 1765556 n/a 1765595 unspecified role unspecified role prey prey n/a 1765593 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8x834-linc00588 1765556 n/a 1765596 unspecified role unspecified role bait bait n/a 1765597 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8x834-ctdspl2 1765556 n/a 1765596 unspecified role unspecified role bait bait n/a 1765598 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q7age0-mettl2a 1765556 n/a 1765599 unspecified role unspecified role prey prey n/a 1765600 unspecified role unspecified role bait bait physical association physical association false false false Table 1 nlef-casp9 1765556 n/a 1765601 unspecified role unspecified role prey prey n/a 1765602 unspecified role unspecified role bait bait physical association physical association false false false Table 1 nlef-dhfr 1765556 n/a 1765603 unspecified role unspecified role prey prey n/a 1765602 unspecified role unspecified role bait bait physical association physical association false false false Table 1 nlef-eri3 1765556 n/a 1765602 unspecified role unspecified role bait bait n/a 1765604 unspecified role unspecified role prey prey physical association physical association false false false Table 1 nlef-lmo4 1765556 n/a 1765602 unspecified role unspecified role bait bait n/a 1765605 unspecified role unspecified role prey prey physical association physical association false false false Table 1 nlef-trnt1 1765556 n/a 1765606 unspecified role unspecified role prey prey n/a 1765602 unspecified role unspecified role bait bait physical association physical association false false false Table 1 q8xal6-ufc1 1765556 n/a 1765607 unspecified role unspecified role bait bait n/a 1765608 unspecified role unspecified role prey prey physical association physical association false false false Table 1 espf_u_-znf626 1765556 n/a 1765609 unspecified role unspecified role bait bait n/a 1765610 unspecified role unspecified role prey prey physical association physical association false false false Table 1 tir-arrb1 1765556 n/a 1765611 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait physical association physical association false false false Table 1 tir-baiap2-1 1765556 n/a 1765613 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait physical association physical association false false false Table 1 tir-hpcal1 1765556 n/a 1765614 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait physical association physical association false false false Table 1 tir-hpcal4 1765556 n/a 1765612 unspecified role unspecified role bait bait n/a 1765615 unspecified role unspecified role prey prey physical association physical association false false false Table 1 tir-ncald 1765556 n/a 1765616 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait physical association physical association false false false Table 1 tir-pde6d 1765556 n/a 1765612 unspecified role unspecified role bait bait n/a 1765617 unspecified role unspecified role prey prey physical association physical association false false false Table 1 tir-stk16 1765556 n/a 1765561 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait physical association physical association false false false Table 1 tir-baiap2-1 1765556 n/a 1765612 unspecified role unspecified role bait bait n/a 1765618 unspecified role unspecified role prey prey physical association physical association false false false Table 1 nlef-hmgn2 1765556 n/a 1765602 unspecified role unspecified role bait bait n/a 1765619 unspecified role unspecified role prey prey physical association physical association false false false Table 1 tir-arrb1-2 1765557 n/a 1765611 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait c-terminal domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig. 5B tir-baiap2-1 1765557 n/a 1765612 unspecified role unspecified role bait bait c-terminal domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1765618 unspecified role unspecified role prey prey physical association physical association false false false Fig. 5B tir-baiap2l1-1 1765557 n/a 1765613 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait c-terminal domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig. 5B tir-hpcal1-2 1765557 n/a 1765612 unspecified role unspecified role bait bait n-terminal region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1765614 unspecified role unspecified role prey prey physical association physical association false false false Fig. 5B tir-hpcal4-2 1765557 n/a 1765615 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait n-terminal region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig. 5B tir-pde6d-2 1765557 n/a 1765617 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait physical association physical association false false false Fig. 5B Interaction appears to be very weak. tir-stk16-2 1765557 n/a 1765561 unspecified role unspecified role prey prey n/a 1765612 unspecified role unspecified role bait bait c-terminal region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig. 5B espb-rbck1-1 1765557 n/a 1765559 unspecified role unspecified role bait bait n/a 1765560 unspecified role unspecified role prey prey physical association physical association false false false espf-mad2l2-1 1765557 n/a 1765562 unspecified role unspecified role prey prey n/a 1765563 unspecified role unspecified role bait bait physical association physical association false false false espf-snx33-1 1765557 n/a 1765564 unspecified role unspecified role prey prey n/a 1765563 unspecified role unspecified role bait bait physical association physical association false false false espf-snx9-4 1765557 n/a 1765565 unspecified role unspecified role prey prey n/a 1765563 unspecified role unspecified role bait bait physical association physical association false false false q7db50-nmi 1765557 n/a 1765567 unspecified role unspecified role prey prey n/a 1765566 unspecified role unspecified role bait bait physical association physical association false false false q8xb62-ric8a-1 1765557 n/a 1765569 unspecified role unspecified role bait bait n/a 1765572 unspecified role unspecified role prey prey physical association physical association false false false q8xb62-mrfap1l1-1 1765557 n/a 1765571 unspecified role unspecified role prey prey n/a 1765569 unspecified role unspecified role bait bait physical association physical association false false false q8xb62-cenph-1 1765557 n/a 1765568 unspecified role unspecified role prey prey n/a 1765569 unspecified role unspecified role bait bait physical association physical association false false false q7db76-rhpn1-1 1765557 n/a 1765584 unspecified role unspecified role bait bait n/a 1765585 unspecified role unspecified role prey prey physical association physical association false false false q8xaj5-dscr4-1 1765557 n/a 1765588 unspecified role unspecified role prey prey n/a 1765587 unspecified role unspecified role bait bait physical association physical association false false false q8xaj5-frmd3-1 1765557 n/a 1765587 unspecified role unspecified role bait bait n/a 1765589 unspecified role unspecified role prey prey physical association physical association false false false q8xaj5-penk-1 1765557 n/a 1765587 unspecified role unspecified role bait bait n/a 1765590 unspecified role unspecified role prey prey physical association physical association false false false Table 1 q8xaj5-ptp4a1-1 1765557 n/a 1765591 unspecified role unspecified role prey prey n/a 1765587 unspecified role unspecified role bait bait physical association physical association false false false q8xbx8-polr2e-1 1765557 n/a 1765595 unspecified role unspecified role prey prey n/a 1765593 unspecified role unspecified role bait bait physical association physical association false false false q8xbx8-drg2-1 1765557 n/a 1765593 unspecified role unspecified role bait bait n/a 1765592 unspecified role unspecified role prey prey physical association physical association false false false q7age0-mettl2a-1 1765557 n/a 1765599 unspecified role unspecified role prey prey n/a 1765600 unspecified role unspecified role bait bait physical association physical association false false false nlef-casp9-1 1765557 n/a 1765602 unspecified role unspecified role bait bait n/a 1765601 unspecified role unspecified role prey prey physical association physical association false false false nlef-dhfr-1 1765557 n/a 1765603 unspecified role unspecified role prey prey n/a 1765602 unspecified role unspecified role bait bait physical association physical association false false false nlef-eri3-1 1765557 n/a 1765602 unspecified role unspecified role bait bait n/a 1765604 unspecified role unspecified role prey prey physical association physical association false false false nlef-lmo4-1 1765557 n/a 1765602 unspecified role unspecified role bait bait n/a 1765605 unspecified role unspecified role prey prey physical association physical association false false false nlef-trnt1-1 1765557 n/a 1765602 unspecified role unspecified role bait bait n/a 1765606 unspecified role unspecified role prey prey physical association physical association false false false nlef-hmgn2-1 1765557 n/a 1765619 unspecified role unspecified role prey prey n/a 1765602 unspecified role unspecified role bait bait physical association physical association false false false q8xa11-znhit1-1 1765557 n/a 1765576 unspecified role unspecified role bait bait n/a 1765583 unspecified role unspecified role prey prey physical association physical association false false false q8xa11-psmc1-1 1765557 n/a 1765576 unspecified role unspecified role bait bait n/a 1765582 unspecified role unspecified role prey prey physical association physical association false false false q8xa11-pih1d1-1 1765557 n/a 1765576 unspecified role unspecified role bait bait n/a 1765581 unspecified role unspecified role prey prey physical association physical association false false false q8xa11-dnajc14-1 1765557 n/a 1765579 unspecified role unspecified role prey prey n/a 1765576 unspecified role unspecified role bait bait physical association physical association false false false q8xa11-clk1-1 1765557 n/a 1765576 unspecified role unspecified role bait bait n/a 1765578 unspecified role unspecified role prey prey physical association physical association false false false q8xa11-cdkn2aipnl-1 1765557 n/a 1765577 unspecified role unspecified role prey prey n/a 1765576 unspecified role unspecified role bait bait physical association physical association false false false tir-stk16-3 1765557 n/a 1765620 unspecified role unspecified role bait bait c-terminal region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1765561 unspecified role unspecified role prey prey physical association physical association false false false Fig. 5B tir-ncald-2 1765557 n/a 1765612 unspecified role unspecified role bait bait n/a 1765616 unspecified role unspecified role prey prey physical association physical association false false false Fig. 5B tir-ncald-3 1765557 n/a 1765620 unspecified role unspecified role bait bait n-terminal region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1765616 unspecified role unspecified role prey prey physical association physical association false false false Fig. 5B tir-hpcal1-3 1765557 n/a 1765620 unspecified role unspecified role bait bait n-terminal region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1765614 unspecified role unspecified role prey prey physical association physical association false false false Fig. 5B tir-baiap2l1-2 1765557 n/a 1765613 unspecified role unspecified role prey prey n/a 1765620 unspecified role unspecified role bait bait c-terminal domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig. 5B tir-baiap2-4 1765557 n/a 1765618 unspecified role unspecified role prey prey n/a 1765620 unspecified role unspecified role bait bait c-terminal domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig. 5B tir-arrb1-1 1765558 n/a 1765611 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A tir-baiap2l1 1765558 n/a 1765613 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A tir-hpcal1-1 1765558 n/a 1765614 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A tir-hpcal4-1 1765558 n/a 1765615 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A tir-ncald-1 1765558 n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765616 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig 5A tir-pde6d-1 1765558 n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765617 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A tir-stk16-1 1765558 n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765561 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A tir-baiap2-1 1765558 n/a 1765618 unspecified role unspecified role prey prey region renilla luciferase renilla luciferase protein tag renilla luciferase undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false n/a 1765612 unspecified role unspecified role bait bait region protein a tag protein a tag protein A protein A undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 5A