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    <entry>
        <source releaseDate="2014-12-22Z">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
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            <attributeList>
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                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
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                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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        </source>
        <experimentList>
            <experimentDescription id="1572304">
                <names>
                    <shortLabel>anonymous-2014h-1</shortLabel>
                    <fullName>Activation of NLRP3 and AIM2 Inflammasomes in Kupffer 
Cells in Hepatic Ischemia/Reperfusion</fullName>
                </names>
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                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844936" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23404" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-liver</shortLabel>
                            <fullName>Mus musculus</fullName>
                        </names>
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                            <names>
                                <shortLabel>liver</shortLabel>
                                <fullName>liver</fullName>
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                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="contact-email" nameAc="MI:0634">sunmee@skku.edu</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2014</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Kim H.Y., Kim S.J., Lee S.M.</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1572305">
                <names>
                    <shortLabel>asc_mouse</shortLabel>
                    <fullName>Apoptosis-associated speck-like protein containing a CARD</fullName>
                    <alias typeAc="MI:0301" type="gene name">Pycard</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Asc</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PYD and CARD domain-containing protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9EPB4" version="SP_102" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042771" secondary="intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" secondary="positive regulation of interleukin-8 production" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" secondary="regulation of inflammatory response" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030838" secondary="positive regulation of actin filament polymerization" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072559" secondary="NLRP3 inflammasome complex" version="SP_183"/>
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                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_075747.3"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050870" secondary="positive regulation of T cell activation" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008385" secondary="IkappaB kinase complex" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_183"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000033056" version="SP_183" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061702" secondary="inflammasome complex" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050830" secondary="defense response to Gram-positive bacterium" version="SP_183"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033516" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042104" secondary="positive regulation of activated T cell proliferation" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032090" secondary="Pyrin domain binding" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" secondary="positive regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051260" secondary="protein homooligomerization" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002588" secondary="positive regulation of antigen processing and presentation of peptide antigen via MHC class II" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900016" secondary="negative regulation of cytokine production involved in inflammatory response" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001238" secondary="positive regulation of extrinsic apoptotic signaling pathway" version="SP_183"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N1F" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" secondary="neuronal cell body" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" secondary="tumor necrosis factor-mediated signaling pathway" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" secondary="protease binding" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043087" secondary="regulation of GTPase activity" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072558" secondary="NLRP1 inflammasome complex" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046983" secondary="protein dimerization activity" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097202" secondary="activation of cysteine-type endopeptidase activity" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032733" secondary="positive regulation of interleukin-10 production" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001056" secondary="positive regulation of cysteine-type endopeptidase activity" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010803" secondary="regulation of tumor necrosis factor-mediated signaling pathway" version="SP_183"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6253348" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071356" secondary="cellular response to tumor necrosis factor" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043281" secondary="regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001773" secondary="myeloid dendritic cell activation" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016505" secondary="peptidase activator activity involved in apoptotic process" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032688" secondary="negative regulation of interferon-beta production" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044351" secondary="macropinocytosis" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090200" secondary="positive regulation of release of cytochrome c from mitochondria" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002230" secondary="positive regulation of defense response to virus by host" version="SP_183"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071347" secondary="cellular response to interleukin-1" version="SP_183"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_183"/>
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                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MGRARDAILDALENLSGDELKKFKMKLLTVQLREGYGRIPRGALLQMDAIDLTDKLVSYYLESYGLELTMTVLRDMGLQELAEQLQTTKEESGAVAAAASVPAQSTARTGHFVDQHRQALIARVTEVDGVLDALHGSVLTEGQYQAVRAETTSQDKMRKLFSFVPSWNLTCKDSLLQALKEIHPYLVMDLEQS</sequence>
            </interactor>
            <interactor id="1572306">
                <names>
                    <shortLabel>casp1_mouse</shortLabel>
                    <fullName>Caspase-1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Interleukin-1 beta convertase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Interleukin-1 beta-converting enzyme</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p45</alias>
                    <alias typeAc="MI:0301" type="gene name">Casp1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Il1bc</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051882" secondary="mitochondrial depolarization" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001819" secondary="positive regulation of cytokine production" version="SP_202"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029030" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072557" secondary="IPAF inflammasome complex" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140448" secondary="signaling receptor ligand precursor processing" version="SP_202"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007613" secondary="memory" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097179" secondary="protease inhibitor complex" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097300" secondary="programmed necrotic cell death" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007520" secondary="myoblast fusion" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000027015" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" secondary="cellular response to interferon-gamma" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016485" secondary="protein processing" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001315" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" secondary="proteolysis" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" secondary="response to lipopolysaccharide" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004197" secondary="cysteine-type endopeptidase activity" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002398" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019900" secondary="kinase binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001774" secondary="microglial cell activation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043005" secondary="neuron projection" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-168638" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033139" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140447" secondary="cytokine precursor processing" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004175" secondary="endopeptidase activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009617" secondary="response to bacterium" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010506" secondary="regulation of autophagy" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_033937.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014070" secondary="response to organic cyclic compound" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097194" secondary="execution phase of apoptosis" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" secondary="regulation of inflammatory response" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072559" secondary="NLRP3 inflammasome complex" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015917" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5620971" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046010" secondary="positive regulation of circadian sleep/wake cycle, non-REM sleep" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097169" secondary="AIM2 inflammasome complex" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002138" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016540" secondary="protein autoprocessing" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000027015" version="SP_202" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016129" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072558" secondary="NLRP1 inflammasome complex" version="SP_202"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-489700" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071310" secondary="cellular response to organic substance" version="SP_202"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MADKILRAKRKQFINSVSIGTINGLLDELLEKRVLNQEEMDKIKLANITAMDKARDLCDHVSKKGPQASQIFITYICNEDCYLAGILELQSAPSAETFVATEDSKGGHPSSSETKEEQNKEDGTFPGLTGTLKFCPLEKAQKLWKENPSEIYPIMNTTTRTRLALIICNTEFQHLSPRVGAQVDLREMKLLLEDLGYTVKVKENLTALEMVKEVKEFAACPEHKTSDSTFLVFMSHGIQEGICGTTYSNEVSDILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVRDSEEDFLTDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSFEQPEFRLQMPTADRVTLTKRFYLFPGH</sequence>
            </interactor>
            <interactor id="1572307">
                <names>
                    <shortLabel>panx1_mouse</shortLabel>
                    <fullName>Pannexin-1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Panx1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9JIP4" version="SP_82" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_062355.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005198" secondary="structural molecule activity" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022840" secondary="leak channel activity" version="SP_147"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q9JIP4" version="SP_147"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000126405" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001819" secondary="positive regulation of cytokine production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" secondary="endoplasmic reticulum" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032059" secondary="bleb" version="SP_147"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-844456" version="SP_147"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9CXS7" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006812" secondary="cation transport" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051015" secondary="actin filament binding" version="SP_147"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000164273" version="SP_147" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055085" secondary="transmembrane transport" version="SP_147"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5RL18" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032730" secondary="positive regulation of interleukin-1 alpha production" version="SP_147"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000031934" version="SP_147" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002931" secondary="response to ischemia" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033198" secondary="response to ATP" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015267" secondary="channel activity" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" secondary="protease binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022829" secondary="wide pore channel activity" version="SP_147"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-112303" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003779" secondary="actin binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006816" secondary="calcium ion transport" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" secondary="calcium channel activity" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005921" secondary="gap junction" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005243" secondary="gap junction channel activity" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000990" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007267" secondary="cell-cell signaling" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039099" version="SP_147"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6272917" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_147"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAIAHLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKSSLQSESGNLPLWLHKFFPYILLLFAILLYLPALFWRFSAAPHLCSDLKFIMEELDKVYNRAIKAAKSARDLDLRDGPGPPGVTENVGQSLWEISESHFKYPIVEQYLKTKKNSSHLIMKYISCRLVTFVVILLACIYLSYYFSLSSLSDEFLCSIKSGVLKNDSTIPDRFQCKLIAVGIFQLLSLINLIVYALLIPVVVYTFFIPFRQKTDILKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISELKSYKCLKVLENIKSNGQGIDPMLLLTNLGMIKMDIIDGKIPTSLQTKGEDQGSQRVEFKDLDLSSEAAANNGEKNSRQRLLNPSC</sequence>
            </interactor>
            <interactor id="1572308">
                <names>
                    <shortLabel>aim2_mouse</shortLabel>
                    <fullName>Interferon-inducible protein AIM2</fullName>
                    <alias typeAc="MI:0301" type="gene name">Aim2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Gm1313</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ifi210</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Interferon-inducible protein 210</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Interferon-inducible protein p210</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q91VJ1" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011237133.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176981.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" secondary="double-stranded DNA binding" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176985.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176975.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176972.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002230" secondary="positive regulation of defense response to virus by host" version="SP_131"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-844615" version="SP_131"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000119465" version="SP_131" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" secondary="activation of innate immune response" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_131"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040205" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032088" secondary="negative regulation of NF-kappaB transcription factor activity" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176987.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JBM" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176976.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001056" secondary="positive regulation of cysteine-type endopeptidase activity" version="SP_131"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_131"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000132253" version="SP_131" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000166137" version="SP_131" refType="transcript"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176999.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044546" secondary="NLRP3 inflammasome complex assembly" version="SP_131"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004021" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001013801.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035690" secondary="cellular response to drug" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176996.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176983.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004020" version="SP_131"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N00" version="SP_131"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6253384" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097169" secondary="AIM2 inflammasome complex" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904270" secondary="pyroptosome complex assembly" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011237144.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176990.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176969.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000037860" version="SP_131" refType="gene"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006496989.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_131"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" secondary="tumor necrosis factor-mediated signaling pathway" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006496982.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176977.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000147604" version="SP_131" refType="transcript"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011237137.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176994.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070269" secondary="pyroptosis" version="SP_131"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_017176971.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035458" secondary="cellular response to interferon-beta" version="SP_131"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MESEYREMLLLTGLDHITEEELKRFKYFALTEFQIARSTLDVADRTELADHLIQSAGAASAVTKAINIFQKLNYMHIANALEEKKKEAERKLMTNTKKRGTQKVENRSQAENCSAASATRSDNDFKEQAATEVCPQAKPQKKQMVAEQEAIREDLQKDPLVVTVLKAINPFECETQEGRQEIFHATVATETDFFFVKVLNAQFKDKFIPKRTIKISNYLWHSNFMEVTSSSVVVDVESNHEVPNNVVKRARETPRISKLKIQPCGTIVNGLFKVQKITEEKDRVLYGIHDKTGTMEVLVLGNPSKTKCEEGDKIRLTFFEVSKNGVKIQLKSGPCSFFKVIKAAKPKTDMKSVE</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-23404-1" id="1572309">
                <names>
                    <shortLabel>panx1-casp1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844945" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23404-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1572304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1572310">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">asc</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844950" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1572305</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
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                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
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                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
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                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1572311">
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                            <shortLabel>n/a</shortLabel>
                        </names>
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                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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                        </biologicalRole>
                        <experimentalRoleList>
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                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
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                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
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                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
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                                    <fullName>physiological level</fullName>
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                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
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                    </participant>
                    <participant id="1572312">
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                            <shortLabel>n/a</shortLabel>
                        </names>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844948" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1572307</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
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                                </xref>
                            </experimentalRole>
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                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
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                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
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                                    <fullName>physiological level</fullName>
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                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
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                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
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                                </xref>
                            </experimentalPreparation>
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                    </participant>
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                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
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                </interactionType>
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                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
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                    <attribute name="comment" nameAc="MI:0612">Anti-Panx1 immunoprecipitated ASC and the p10 subunit of caspase-1 (Fig. 2A).</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-23404-2" id="1572313">
                <names>
                    <shortLabel>pycard-aim2-2</shortLabel>
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                    <participant id="1572314">
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                            <shortLabel>n/a</shortLabel>
                        </names>
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                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
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                                <fullName>unspecified role</fullName>
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                                    <fullName>prey</fullName>
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                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
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                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
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                    </participant>
                    <participant id="1572315">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">asc</alias>
                        </names>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9844954" refType="identity" refTypeAc="MI:0356"/>
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                        <interactorRef>1572305</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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                            </participantIdentificationMethod>
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                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
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                                    <fullName>bait</fullName>
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                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
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                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
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                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
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                </interactionType>
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                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
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                    <attribute name="figure legend" nameAc="MI:0599">f3c</attribute>
                    <attribute name="comment" nameAc="MI:0612">Anti-Panx1 immunoprecipitated ASC and the p10 subunit of caspase-1 (Fig. 2A).</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
