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    <entry>
        <source releaseDate="2014-06-09+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1537623">
                <names>
                    <shortLabel>anonymous-2014x-1</shortLabel>
                    <fullName>Functional characterization of the tryptophan synthase β-
subunit paralog TrpB2 in the hyperthermophilic archaeon
Thermococcus kodakarensis</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="24835339" refType="primary-reference" refTypeAc="MI:0358"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-22597" refType="imex-primary" refTypeAc="MI:0662"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>molecular sieving</shortLabel>
                        <fullName>molecular sieving</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Gel Filtration</alias>
                        <alias typeAc="MI:0303" type="go synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Size Exclusion Chromatography</alias>
                        <alias typeAc="MI:1041" type="synonym">Gel Filtration</alias>
                        <alias typeAc="MI:1041" type="synonym">Sizing column</alias>
                    </names>
                    <xref>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="contact-email" nameAc="MI:0634">atomi@sbchem.kyoto-u.ac.jp</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2014</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Hiyama T., Sato T., Imanaka T., Atomi H.</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1537624">
                <names>
                    <shortLabel>trpb1_theko</shortLabel>
                    <fullName>Tryptophan synthase beta chain 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">trpB1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">trpB</alias>
                    <alias typeAc="MI:0305" type="locus name">TK0257</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9YGB0" version="SP_96" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001926"/>
                    <secondaryRef db="ensemblbacteria" id="BAD84446" version="SP_133" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000162" secondary="tryptophan biosynthetic process" version="SP_133"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036052"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006654"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023026"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006653"/>
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                    <secondaryRef db="ensemblbacteria" id="TK0257" version="SP_133" refType="gene"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_133"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="69014">
                    <names>
                        <shortLabel>theko</shortLabel>
                        <fullName>Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Pyrococcus kodakaraensis (strain KOD1)</alias>
                    </names>
                </organism>
                <sequence>MDDMFFGRFGGQFVPETLIEPLKKLERAYKKFKDDPEFNETLEYYLRNWAGRPTPLYYAERLSKKLGGAKIYLKREDLLHGGAHKTNNGIGQALLAKFMGKERLIAETGAGQHGVATAMAGALLGMKVDVYMGAEDVERQKMNVFRMGLLGARVIPVESGSRTLKDAINEALRDWVATFEYSHYLIGSVVGPYPYPVIVRDFQSVIGREAREQILEAEGTLPDAVVACVGGGSNAMGIFYPFVNDRVRLIGVEAGGKGLETGLHAASLNAGELGVFHGMLSYFLQNEEGQITPTHSVSAGLDYPGVGPEHAYLKDSGRAEYVTVTDEEALRAFHELSRTEGILPALESAHAVAYAMKIAPEMDKDEIIIVNLSGRGDKDLDIVRRVGNV</sequence>
            </interactor>
            <interactor id="1537625">
                <names>
                    <shortLabel>trpa_theko</shortLabel>
                    <fullName>Tryptophan synthase alpha chain</fullName>
                    <alias typeAc="MI:0301" type="gene name">trpA</alias>
                    <alias typeAc="MI:0305" type="locus name">TK0258</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9YGA9" version="SP_95" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011060"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002028"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004834" secondary="tryptophan synthase activity" version="SP_125"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_011249213.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013785"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="69014">
                    <names>
                        <shortLabel>theko</shortLabel>
                        <fullName>Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Pyrococcus kodakaraensis (strain KOD1)</alias>
                    </names>
                </organism>
                <sequence>MFEKGSLIPYLTAGDPSVEKTLEFLLAVEEFAGLIELGIPFSDPMADGKTIQESHYRALRNGFKLDDTFRILREFRRHSSTPVILMTYYNPVFRTGVKKFLGEAKASGADGILVVDLPVSHAGEFLDAAKEEGLKTVFLAAPNTPDERLREIDKASTGFVYLISLYGTTGARDRLPETAFEFVRRARKICNNKLAVGFGVSRREQVEELLKAGADGVVVGSALIELISRSENPVEELRRKVAELSGYSRAL</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-22597-1" id="1537626">
                <names>
                    <shortLabel>trpa-trpb1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-9520218" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-22597-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1537623</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1537627">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">TrpB1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9520244" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1537624</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1537628">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">TrpA</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-9520243" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1537625</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
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                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
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                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
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                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">sf2</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
