IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ singh-2014-1 Protein interactome analysis of 12 mitogen-activated protein kinase kinase kinase in rice using a yeast two-hybrid system. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Singh R., Lee J.E., Dangol S., Choi J., Yoo R.H., Moon J.S., Shim J.K., Rakwal R., Agrawal G.K., Jwa N.S. Uniprot Ac of proteins were mapped according to the following strategy: KOME accessions were extracted from Table S3 and used to retrive protein sequences from http://systemsbiology.cau.edu.cn/agriGOv2/download/129.fasta . Protein sequences were blasted against Uniprot and accessions were obtained. In the case of Ty3 as the balst result was < 90% an internal interactor was created. For OsEp1 and OsRingE3 the sequences were not available and the interactions were not captured. nsjwa@sejong.ac.kr rice (Oryza sativa japonica cultivar, Dongjin) cDNA library Proteomics (1615-9853) 2014 Only protein-protein interactions imex curation singh-2014-4 onion-epidermis Allium cepa epidermis A thin surface layer of tissue in higher plants formed by growth of a primary meristem. bifc bimolecular fluorescence complementation bifc tag fluorescence tag visualisation by fluorescence tag fluorescence Singh R., Lee J.E., Dangol S., Choi J., Yoo R.H., Moon J.S., Shim J.K., Rakwal R., Agrawal G.K., Jwa N.S. Uniprot Ac of proteins were mapped according to the following strategy: KOME accessions were extracted from Table S3 and used to retrive protein sequences from http://systemsbiology.cau.edu.cn/agriGOv2/download/129.fasta . Protein sequences were blasted against Uniprot and accessions were obtained. In the case of Ty3 as the balst result was < 90% an internal interactor was created. For OsEp1 and OsRingE3 the sequences were not available and the interactions were not captured. nsjwa@sejong.ac.kr rice (Oryza sativa japonica cultivar, Dongjin) cDNA library Proteomics (1615-9853) 2014 Only protein-protein interactions imex curation q10s67_orysj OSNPB_030132800 LOC_Os03g04050 Os03g0132800 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MGCCGSSLQAGTHPEKPPGMAAPPQRPSFSLNQHQAPGSAAAQGVGRGEVPAFAEFSLAELRAATGGFAAENIVSESGEKAPNFVYRGRLQRTRRAIAVKKFPKMAWPDPKQFEEEAKGVGKLRHRRLANLIGYCCDGDERLLVAEFMPNDTLAKHVFHWENQTIEWAMRLRVAHHIAEALDYCSSNERPLYHDLNAYRVLFDENGDPRLSCFGLMKNSRDGKSYSTNLAYTPPEYLRNGRVTPESVIFSFGTVLLDLLSGKRIPPSHALDMIRGKNIQVLLDSHLEGKYSTEEATALVDLASQCLQYEPRDRPNTGKLVSILDPLQTKLEVPSYEMLGIPKHEEEAPPAPAPAPAPQPQHPLSPMGEACSRMDMTAIHQILVATHYRDDEGTNELSFQEWTQQMRDMLDARKRGDFAFRDKDFKTAIECYTQFVDVGTMVSPTVYARRSLCHLMSDQPDAALRDAMQAQCVYPDWPTAFYMQAVALSKLNMQSDAMDMLNEASQLEEKRQERLWSKDASAQSPLRLKGLC b9g9x3_orysj Protein kinase domain-containing protein OsJ_33308 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MPAWWKRGKGKKGKGGSAAAGEEEEGRRKAGSFDEALLAGKQSREEKEVVVVGHPLPRPASLPAPSAASSSAAGSASASSARQLLARLVGGVRRAAGSRDLQVCLLVALALSSPGKVPDASYVLPGRTLAIDSRRQNLAVEEGRFFANNQGLEHPRLSETSVSPRKESYLHNLDLSNDRTAYCHGRKSTEIVFSTRVPISPPGSKGQIPCPTSPVQSRAFGQCPGSPTARQDDSRSSSSPHPLPRPPGSPCSSSRVVSSQWKKGKLLGSGTFGQVYQGFNSEGGQMCAIKEVKVISDDSNSKECLRQLHQEIVLLSQLSHPNIVQYYGSDLSSETLSVYLEYVSGGSIHKLLQEYGAFGEAVLRNYTAQILSGLAYLHGRNTVHRDIKGANILVDPNGDIKLADFGMAKHISAHTSIKSFKGSPYWMAPEVIMNTNGYSLSVDIWSLGCTIIEMATARPPWIQYEGVAAIFKIGNSKDIPDIPDHLSFEAKNFLKLCLQRDPAARPTAAQLMEHPFVKDLVANRSFRSGMTRDTFPTSFDGKGAMVQTSNRSLSPLRDPDLTMRNLQVPTSAIPSISTRRISAINPSNVRMNMSLPVSPCSSPLRQYRQSNRSCMPSPPHPAYSAGAANYSPINNALYPKRPSNHVPDPWLEISQLKAPPFDSPRRL q6z9x3_orysj OSNPB_080407200 Os08g0407200 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MWPSDIWKAHAGSSQSEGSALDMERNGCNHNCCPSPLQPIASGGQHSESSAAYFSWPTSTLMHGSAEGRANYFGNLQKGVLPGHLGRLPTGQRATTLLDLMIIRAFHSKILRRFSLGTAIGFRIKKGTLTDTPAILVFVARKVHRKWLSPTQCLPAHLEGPGGVWCDVDVVEFSYYGAPAPTPKEQLYDELVDGLRGSDPSIGSGSQVASLETYGTLGAIVKSRTGNKQVGFLTNRHVAVDLDYPNQKMFHPLPPNLGPGVYLGAVERATSFITDDVWYGIYAGTNPETFVRADGAFIPFADDYDITSVNTSVKGVGVIGDVKAIDLQSPISSLIGRQVVKVGRSSGLTTGTVVAYALEYNDEKGICFFTDFLVVGENQQTFDLEGDSGSLIILTGKDGEKPQPIGIIWGGTANRGRLKLKSGQGPENWTSGVDLGRLLDLLELDLITTSEGLQEALEEQRIILAAAAAAANSTAGESSPVAGPQENEKVDKIYEPLGINIQQLPRDNSATSTGPDEFHVDTVEGVTNVEERQFLIGMSPAREGQEANGDLNNLAELENSPEDICFSLHLGEREPKRLRSDSSLDIDLQK q0d8z1_orysj OSNPB_070119000 Os07g0119000 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MPLTLRARASWSPQASVMPTWWKRSKSAFQRSSAVSSAPASPARASTSSCAAPGRRSAAGRCADDAGGLLLARRRQLTRQRKLRHVDDIGVGLESLGLVVANSSPPPRGRASTSAAVGHPVSIPIARSASSAEFRAVHQPPPRAATAASPVLLPLPLPSPKPVESDTSEPDVGGERATRVTSQIVQNFPDNNNNLPDNSSKRTTTSSHHRKVFREKFQDKSSTETANFRLNIPAKSAPSSGFSSPVCSPRRFSNAEYTTPTAQGPQAWSAPSVRSVDSMATSSPRISPEIYTGVTEQSTFSNSLRSPILMSKNSSAPPSPLHPKLFPENNMSRIEGNGNVSFHPLPRPPGAINSMQTSIVNQSAPKVEMPSVAGQWQKGRLLGSGTFGCVYEATNRQTGALCAMKEVNIIPDDAKSAESLKQLEQEIKFLSQFKHENIVQYYGSDTFEDRFYIYLEYVHPGSINKYVKQHYGAMTESVVRNFTRHILRGLAFLHGQKIMHRDIKGANLLVDVSGVVKLADFGMAKHLSTAAPNLSLKGTPYWMAPEMVQATLNKDVGYDLAVDIWSLGCTIIEMFNGKPPWSDLEGPAAMFRVLHKDPPIPDNLSHEGKDFLQFCFKRNPAERPTASELLEHPFIRNSSHYNKHGSIHSFAGIKSNDNNNGNGSRDKAASKSDSCVKGKITVGEPTNARPSESSAFRLTPLSIQEVAPNFSSRPLGLTSNPSPSANLVNTVYFPIANSQRSPLPRPNEKEALF q10e61_orysj OSNPB_030707300 LOC_Os03g49960 Os03g0707300 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MRDPFSAPVDFNNENHRAGNELTRTNMPLSVGDYGLQNGDATTFAVNTDTLVRHQLQGASLQNDLTAEDSITRLMDPETKGLYFRSRSQEEEILLLRKQIADASVKELQLLSEKHILERKLFDLRMAVDEKQEDAISGALKQLSQKKGHVEENMRLANDLKGEEEELYFFTSSLLSMLAEYNVRPPQINASAITAGTKRLYHQMQWKIKYLNDSLGEITQPGHIYNNPNHQQATPLRHEPSSSYNTDATRNNFHQYAQDPNDRNTGQMYHGSNYHQEIVAATPSNYFEENNGPREVRLDDSQFYRQDNQEYSADDDPLPGIEGFQIVGEPRPGFTLTACGFPTNGTTLCNFQWVRYLDNGTRQSIEGATMYDYVVTADDVDTLLAVDCTPMDDNTRQGELVTEYANNGSKITCDPEMQNTIDMHISNGRAHFNLLVLGYSSDEWELAILTLKRTGYHIKVKDEVLTEEKYSSNLQTKIPNGRTTQFVLVSSGGVNIPFNTQGISEPNNEDSDVRLRDLIVLVLRTFQSKALDAKRKGKV ran2_orysj GTP-binding nuclear protein Ran-2 RAN2 Ras-related nuclear protein 2 OJ1268_B08.8 OsJ_018847 Os05g0574500 LOC_Os05g49890 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MALPNQGTVDYPSFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFTTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTSRLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEISAKSNYNFEKPFLYLARKLAGDPNLHFVEAVALKPPEVPIDLAMQQQHEAELAAAAAQPLPDDDDDLIE q6asr0_orysj OSNPB_050147500 Os05g0147500 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MAGVAALFASPAFPFPSTSSVSSCSCRFRPAVARAPRHQPPGRRVTRRFDEVEGVSKRRRGIGGGGGGGSQASSSSSRKDRGLAVDFKESQVSDFEDLEEDKFLNAVVKVYCTHIAPDYGLPWQKQRQHASTGSAFMIGDGKLLTNAHCVEHDTQVKVKRRGDDKKYIAKVLARGIECDLALLSVENEEFWRGTEPLQLGRLPCLQDSVTVVGYPLGGDTISVTKGVVSRIEVTPYAHGTSDLLGIQIDAAINPGNSGGPAFNDHGECIGVAFQVFRSDEAENIGYVIPTTVVSHFLNDYQKNGKYTGFPCLGVLLQKLENPALRESLKVPSSEGVLVRRVEPTAPASKVLRKGDVITSFDGVAVGCEGTVPFRSTERIAFRYLTSQKYAGDVAQLGIIRAGNTMKVQTVLQPRKHLVPFHVEGGQPSYLIVAGLVFTPLTEPFIEEECEETLGLKLLAKARYSLSTFEGEQIVIVSQVLAHEVNIGYEHMGNQQVIKLNGTVVKNIHHLAHLVDNCKDKFLTFEFEDDFLVVLDREEATTASSDILKEHAIPSVRSSDLSEPYVDTEQEIQKPNDDFGDSPVTNYEMGVDCLLWA q0jd14_orysj OSNPB_040437600 Os04g0437600 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MPAWWPRKSRSKAKGVGKPPGAGAASAASSPRKSLDLVDLSASPSVTPRAREKARSLDSPSAAAPRHGGGRCGGGFGEVGYKLPVPVGDAGPGGQGQGQEPELEPAPVRFEENGDVVGGVAGDASSEELSVCSHDSSDEATDQQVCRSTDPASFVRGRNMPSDSHKILNEDNHFMSYSMPREHRKFFEVPVTNMGELHLHCDDLSTSETSSRGRMLPEDFLAPRTRSLSPGPKGHTFAVNNVNSREFGFSPRSPVKMMDGLKSPPHPLPLPPGPATCSPLPPSPTAYSPHPLGPTTCLQSESQWKKGKLLGSGTFGQVYLGFNSENGQFCAIKEVQVISDDPHSKERLKQLNQEIDMLRQLSHPNIVQYYGSEMTDDALSIYLEFVSGGSIHKLLREYGPFKEPVIRNYTGQILSGLAYLHGRNTVHRDIKGANILVGPNGEVKLADFGMAKHISSFAEIRSFKGSPYWMAPEVIMNGRGYHLPVDIWSLGCTIIEMATAKPPWHKYEGVAAIFKIANSKEIPEIPDSFSEEGKSFLQMCLKRDPASRFTATQLMDHPFVQDHPAVRAAKSGALRNAFAPADGTHTTSNREFSRKSITPLKDIGVSARDFTGFSTAVPSPHTASPISVVRTNMSLPVSPCSSPLRQFKQSNWSCLPSPPHPTFSNGATSYNLSSYMMNETRRIPTISDTWQDISQLKVQSPYGSPKRF q7xr00_orysj OSNPB_040660500 Os04g0660500 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MASRQHNAQFHKNKTLDNKYMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPQEDLNIIMQEIDLLKNLNHKNIVKYLGSLKTRSHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLTEADINTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLTCAPPYYDLQPMPALFRIVQDVHPPIPEGLSPEITDFLRQCFQKDSIQRPDAKTLLMHPWLQNSRRALPSLRQPVQSPSTVRDIDEDDEGSSGDNHSGFSGPPRDTQTPTASGLEQEDGRKDLVSESARQDIPDEFHDGMLKTTGSSSSNDVELMKDNVVLNKDPTLVFHEKLSLESSLGATDLNGKLTHEVSQDGPPNKLTSSGQESRKSDGKYVEDESKDGSSLEDGDAFSFQAGGQNINFQKEAKTSVEMANELSRFSDTPGDASFDDLFPPKKRGDHGAEASTSTTGEELQYNGAQNDLAKELKTRMAQKQKENDTEHMNGGKLLEYVMRLREEDIDGTAFDETIPGESLFPLQSVEYSKIVAQLKPGESEDVILSACQKLVSIFNQRPEQKQIYVSQNGFLPLMELLELPKNRIITSVLQLINQIVKDNTTFLENACLVGLIPVVMNFAVPDRAKEVRVQASRFLQQLCQASTLTLQMFIACQGIPVLVSFLEPDYAKYREMVHLAIDGIWQVFKLQHSTPRNDFCRIAAKNGILLRLVNTLHSLNEATRFASISGSGASVTQNGSTPRRRSGQLDPPMLEISKTRLDHHHSSGSLQSLQADADRHHIIMDPSASPRFTDMAAAGHMERNDNDPIRPQRLSVSAGRTSTDRSPKHIELVSNGHSSGQNDQIRPLLSLLEKEPPSRHVSGQLDYVRHLSGLERHESILPLLHASTERKTNGELDLLMAEFAEVSRQGRENGNLDSNIKTSNRVPSMKYAPSSGPTTSNEGASTSGAASQTASGVLSGSGVLNARPGSTTSSGLLAQMVSMSADVAREYLEKVADLLLEFAQADTVVKSLMSSQSLLARLFQMFNKIEPPILLKILRCINHLSGDPNCLETLQRTDAIKHLIPILELHDGPLVYQIHSEVLNALFNLCKINKRRQEQAAENGIIPHLMNFVMSDSPLRQYALPLLCDMAHASRNSREQLRAHGGLDVYLNLLEDDAWACTALDSIAVCLSHDNDHRKVEQALLKKDAIQKLVKFFQDCPEQYFVHILDAFLKIITKSSRINTAMATNGLTTLLIARLDHREAIARLTLLKLIKVVYEHHPRPKQLIVENDLPQKLQNLIEERRDGQRGGQQVLVKQMATSLLKALHINTVL q2qyd2_orysj LOC_Os12g03070 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MEAAVATPSLLFSSPTPRRPSSCLSLPPPCSSSYASNGAKLQQPRLQFVSQLTSRNSNGSGRRSISILSLRCSSSGTDSASSSATSERWVLEPAGDGDWRHIGYRVARPGGFQIASEAAVTVGRVPEQADIVLSVATVSGTHARLEKKEGSLLVTDLESTNGTYINERRLSPGFPTPIDPGSLLIFGDIHLAMFRVSKMVVDVPSDASGAEQEAAETAQVSAAAQQTN q2rb31_orysj LOC_Os11g03390 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MEAAVATPSLLFSSPTPRRPSSCLPPPPPCSSSSSSYASHGFKLLQPQLLFINRLTSRNSNGSSRRSISILSLRCSSSGTDSASSSATSERWVLEPAGDGDWRHIGYRVARPGGFQIASEAAVTVGRVPEQADIVLSVATVSGTHARLEKKEGSLLVTDLESTNGTYINERRLTPGFPTPIDPGSLLIFGDIHLAMFRVSKMIVDVSSDTNEAEQEAETAQVSAATQQTN ty3_orysj retrotransposon protein, putative, Ty3-gypsy subclass protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MGEEEEDPDWLRAFQPPTTSTVMLSSGSDDSPENSPTRTTPSGEEQKGENKASSDHAGDGDAAALNKGKKATPTRRKTPTSQEDAFDKDEKPTMESNQDKPPKRSSPRELQIQAKAKTRKTLSKTPKKKLVKPPSGSNASKVTGPKAGPDQIDDTLEHQEEGVAEEDMQDKLTEHSVSQRLPLIIPDKIQRSKALIECDGDSIDLSGDVGAVGRIIISNSPNGNQELLLDLKGTIYKSTIVPSRTFCVVSVGQTEAKVVDDNINLL KOME Accession: AK287797 q67va4_orysj OSNPB_060234100 Os06g0234100 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MDNHELASTSSPKRKPGRRPGRKPKPPPAPSPAAAPAPAAENGTHDPASGQKRKRGRKPKPPAAAAAAASSDGHHHPSSPLAAAVSASDSPDPASSPAPRGRGRKSRRGRPEPPSDAGAAPHAPPSPPRRGAKKGAAANAKKAAAEVPVVEPLRWEQVAKVMPSMDAVVKVFCVHTEPNFSLPWQRKRQYSSSSSGFIIGGHRVLTNAHSVEHYTQVKLKKRGSDTKYLATVLAIGTECDIAMLTVEDDEFWKGVSPLEFGSLPALQDAVTVVGYPIGGDTISVTSGVVSRIEILSYVHGSTELLGLQIDAAINSGNSGGPAFNDKGKCVGIAFQSLKHEDVENIGYVIPTPVINHFIQDYEKSGEYTGFPILGIEWQKMENPDLRKAMGMKSDQKGVRVRRVEPTAPESGCLQPSDIILSFDGIDIANDGTVPFRHGERIGFSYLISQKYTGEKAHVKILRNSKVLEFNIKLATHKRLIPAHIKGRPPSYYIVAGFVFMVVSVPYLRSEYGKDYEYDAPVKLLDKHLHAMAQSPDEQLVVVSQVLVADINIGYEEIVNIQVLSFNGKPVKNLKHLATMVEDCNEEYLKFDMDYDQLVVLEAKTAKAATQDILTTHCIPSAMSEDLRT q6l5b1_orysj OJ1206_C08.14 OJ1345_B12.2 protein protein orysj Oryza sativa subsp. japonica (Rice) Rice MPRRGRRGDEAQVGLSQEHAGCRILGVGRRRRGRRHAGELGREDHGAGRPLLCRAGLGIRRWLDRRHEQPIRTSHRGG mekk8_apk1-1 1500574 N/A 1500576 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500577 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk11-pep-1 1500574 N/A 1500578 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500579 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk11-ep2-1 1500574 N/A 1500580 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500579 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk11-grf-1 1500574 N/A 1500581 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500579 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk16-degp6-1 1500574 N/A 1500582 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500583 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk24-mekk24-1 1500574 N/A 1500584 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500584 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk24-fha1-1 1500574 N/A 1500585 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500584 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk24-fha2-1 1500574 N/A 1500586 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500584 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk24-ty3-1 1500574 N/A 1500587 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500584 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk55-degp10-1 1500574 N/A 1500588 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed N/A 1500589 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association false false false Table 1, Table S3, Fig.1 mekk11-pep-2 1500575 N/A 1500578 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYNE n-venus n-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1500579 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYCE c-venus c-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 1, Fig.1B mekk55-degp10-2 1500575 N/A 1500588 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYNE n-venus n-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1500589 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYCE c-venus c-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 1, Fig.1B mekk11-ep2-2 1500575 N/A 1500580 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYNE n-venus n-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1500579 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYCE c-venus c-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 1 mekk11-grf-2 1500575 N/A 1500581 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYNE n-venus n-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1500579 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYCE c-venus c-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 1 mekk24-fha1-2 1500575 N/A 1500585 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYNE n-venus n-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1500584 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYCE c-venus c-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 1 mekk24-fha2-2 1500575 N/A 1500586 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYNE n-venus n-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false N/A 1500584 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed VYCE c-venus c-venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Table 1