UniProt UniProt http://www.uniprot.org bajaj-2008-6 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. in vitro In vitro pull down pull down weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-4 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-1 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-2 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. human-lcl1 Homo sapiens LCL-1 lymphoblastoid cell line, in vitro transformed EBV-positive lcl1 LCL-1 lymphoblastoid cell line, in vitro transformed EBV-positive anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-3 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. human-lcl2 Homo sapiens LCL-2 lymphoblastoid cell line, in vitro transformed EBV-positive lcl2 LCL-2 lymphoblastoid cell line, in vitro transformed EBV-positive anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-5 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-7 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. human-u2-os Human U2-OS osteosarcoma cell line u2-os U2-OS osteocaroma cell line Not in CAPRI and no primary literature reference fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions bajaj-2008-8 Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein. human-bjab_e3c10 Homo sapiens human burkitt lymphoma cell line expressing EBNA3C bjab_e3c10 Burkitt lymphoma cell line expressing EBNA3C fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Bajaj B.G., Murakami M., Cai Q., Verma S.C., Lan K., Robertson E.S. Viral EBNA6/EBNA3C has been mapped to the UniProt Epstein-Barr virus reference proteome strain erle@mail.med.upenn.edu J. Virol. (0022-538X) 2008 imex curation Only protein-protein interactions ebna6_ebvb9 Epstein-Barr nuclear antigen 6 EBNA6 Epstein-Barr nuclear antigen 3C Epstein-Barr nuclear antigen 4B BERF3-BERF4 protein protein ebvb9 Epstein-Barr virus (strain B95-8) (HHV-4) Human herpesvirus 4 HHV-4 MESFEGQGDSRQSPDNERGDNVQTTGEHDQDPGPGPPSSGASERLVPEESYSRDQQPWGQSRGDENRGWMQRIRRRRRRRAALSGHLLDTEDNVPPWLPPHDITPYTARNIRDAACRAVKQSHLQALSNLILDSGLDTQHILCFVMAARQRLQDIRRGPLVAEGGVGWRHWLLTSPSQSWPMGYRTATLRTLTPVPNRVGADSIMLTATFGCQNAARTLNTFSATVWTPPHAGPREQERYAREAEVRFLRGKWQRRYRRIYDLIELCGSLHHIWQNLLQTEENLLDFVRFMGVMSSCNNPAVNYWFHKTIGNFKPYYPWNAPPNENPYHARRGIKEHVIQNAFRKAQIQGLSMLATGGEPRGDATSETSSDEDTGRQGSDVELESSDDELPYIDPNMEPVQQRPVMFVSRVPAKKPRKLPWPTPKTHPVKRTNVKTSDRSDKAEAQSTPERPGPSEQSSVTVEPAHPTPVEMPMVILHQPPPVPKPVPVKPTPPPSRRRRGACVVYDDDVIEVIDVETTEDSSSVSQPNKPHRKHQDGFQRSGRRQKRAAPPTVSPSDTGPPAVGPPAAGPPAAGPPAAGPPAAGPPAAGPPAAGPRILAPLSAGPPAAGPHIVTPPSARPRIMAPPVVRMFMRERQLPQSTGRKPQCFWEMRAGREITQMQQEPSSHLQSATQPTTPRPSWAPSVCALSVMDAGKAQPIESSHLSSMSPTQPISHEEQPRYEDPDAPLDLSLHPDVAAQPAPQAPYQGYQEPPAPQAPYQGYQEPPPPQAPYQGYQEPPAHGLQSSSYPGYAGPWTPRSQHPCYRHPWAPWSQDPVHGHTQGPWDPRAPHLPPQWDGSAGHGQDQVSQFPHLQSETGPPRLQLSLVPLVSSSAPSWSSPQPRAPIRPIPTRFPPPPMPLQDSMAVGCDSSGTACPSMPFASDYSQGAFTPLDINATTPKRPRVEESSHGPARCSQATAEAQEILSDNSEISVFPKDAKQTDYDASTESELD myc_human Myc proto-oncogene protein BHLHE39 Transcription factor p64 MYC Proto-oncogene c-Myc Class E basic helix-loop-helix protein 39 protein protein human Homo sapiens Human MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA myc-ebna6-6 1512801 n/a 1512809 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro n/a 1512810 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) physical association physical association false false false 2B ebna6-myc 1512801 n/a 1512810 unspecified role unspecified role prey prey in vitro translated in vitro translated protein in vitro translated region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro n/a 1512809 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) physical association physical association false false false 2C ebna6-myc-3 1512801 n/a 1512810 unspecified role unspecified role prey prey in vitro translated in vitro translated protein in vitro translated region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro n/a 1512809 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecoli Escherichia coli (strain K12) physical association physical association false false false 3E myc-ebna6-3 1512802 n/a 1512810 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) n/a 1512809 unspecified role unspecified role prey prey human-lcl2 Homo sapiens LCL-2 lymphoblastoid cell line, in vitro transformed EBV-positive lcl2 LCL-2 lymphoblastoid cell line, in vitro transformed EBV-positive physical association physical association false false false 1D myc-ebna6-4 1512802 n/a 1512809 unspecified role unspecified role prey prey human-bjab_e3c10 Homo sapiens human burkitt lymphoma cell line expressing EBNA3C bjab_e3c10 Burkitt lymphoma cell line expressing EBNA3C n/a 1512810 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecoli Escherichia coli (strain K12) physical association physical association false false false 1D myc-ebna6 1512803 n/a 1512810 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection c-terminus flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false n/a 1512809 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection physical association physical association false false false 1A, 3B-D myc-ebna6-1 1512804 n/a 1512809 unspecified role unspecified role prey prey n/a 1512810 unspecified role unspecified role bait bait physical association physical association false false false 1E myc-ebna6-2 1512805 n/a 1512809 unspecified role unspecified role prey prey n/a 1512810 unspecified role unspecified role bait bait physical association physical association false false false 1E myc-ebna6-5 1512806 n/a 1512809 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n/a 1512810 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection c-terminus flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false physical association physical association false false false 2A ebna6-myc-1 1512807 n/a 1512810 unspecified role unspecified role neutral component neutral component nucl transfection nucleic acid transfection nucl transfection n/a 1512809 unspecified role unspecified role neutral component neutral component nucl transfection nucleic acid transfection nucl transfection colocalization colocalization false false false 4A ebna6-myc-2 1512808 n/a 1512810 unspecified role unspecified role neutral component neutral component n/a 1512809 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 4A