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<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2013-06-19+01:00">
            <names>
                <shortLabel>HPIDb</shortLabel>
                <fullName>Host Pathogen Interaction database</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1335" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6598961" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.agbase.msstate.edu/hpi/main.html</attribute>
                <attribute name="postalAddress">http://www.agbase.msstate.edu/hpi/main.html</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1385304">
                <names>
                    <shortLabel>qi-1998-1</shortLabel>
                    <fullName>FK-binding protein is associated with the ryanodine receptor of skeletal muscle in vertebrate animals.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="9857007" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6656578" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9031">
                        <names>
                            <shortLabel>chick</shortLabel>
                            <fullName>Gallus gallus (Chicken)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Chicken</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>competition binding</shortLabel>
                        <fullName>competition binding</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0405" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608490" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>tag visualisation</shortLabel>
                        <fullName>tag visualisation</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0866" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1372415" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Qi Y., Ogunbunmi E.M., Freund E.A., Timerman A.P., Fleischer S.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">Sidney.Fleischer@vanderbilt.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1998</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1385305">
                <names>
                    <shortLabel>fkb1a_human</shortLabel>
                    <fullName>Peptidyl-prolyl cis-trans isomerase FKBP1A</fullName>
                    <alias typeAc="MI:0301" type="gene name">FKBP1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FK506-binding protein 1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rotamase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Immunophilin FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">12 kDa FK506-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Calstabin-1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P62942" version="SP_40" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1D7H" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKH" version="SP_182"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166208" version="SP_182"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000400137" version="SP_182" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173789" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005527" secondary="macrolide binding" version="SP_182"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29710N"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKI" version="SP_182"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKT" version="SP_182"/>
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                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000792.1"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKD" version="SP_182"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MDY" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032515" secondary="negative regulation of phosphoprotein phosphatase activity" version="SP_182"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I7Q" version="SP_182"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE</sequence>
            </interactor>
            <interactor id="1385306">
                <names>
                    <shortLabel>q90984_chick</shortLabel>
                    <alias typeAc="MI:0301" type="gene name">RyR1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q90984" version="TrEMBL_60" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008144" secondary="drug binding" version="TrEMBL_91"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009460"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015278" secondary="calcium-release channel activity" version="TrEMBL_91"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014808" secondary="release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="TrEMBL_91"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015643" secondary="toxic substance binding" version="TrEMBL_91"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014802" secondary="terminal cisterna" version="TrEMBL_91"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="TrEMBL_91"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219" secondary="ryanodine-sensitive calcium-release channel activity" version="TrEMBL_91"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6661884" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="TrEMBL_91"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="TrEMBL_91"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9031">
                    <names>
                        <shortLabel>chick</shortLabel>
                        <fullName>Gallus gallus (Chicken)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Chicken</alias>
                    </names>
                </organism>
                <sequence>KDVGHYRMAPPDAPGGLGDIGEPPGAEPPTPEGTPILRRKIGEDGKEVVEEPQKEEEAAAETEKADTENGEKGDGGAEGGPEVETPEKQQKAPPPRERKEPPPPEAFEFWTELEVQRVKFLNYLSRNFYNLRFLALFLAFAINFILLFYKVSERPPGMEEAEVEGSGMAAVLDGIGDFGDGGDGDGDGGEGAEEPSVVYYCLEESTGYMQPPARLAVAHTIVAFLCIIGYNCLKIPLVIFKREKEVARRLEFSGLYITEQPPDDDVKGQWDRLVLNAQSFPSNYWDKFVKRKVLEKYGDIYGRERIAELLGMELSSLEIGARGERKPPPDNSVLTWITSIDIRYQIWKFGVIFTDNSFLYLTWYMAMSLLGHYNNFFFAAHLLDIAMGVKNVRTILSSVTHNGKQLAMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEEPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFLCGIGSDYFDTTPHGFETHTLEEHNLANSMFFLMYLINKDDTEHTGQESYVWKMYQERCWDFFPAGDSFRKQYEDQLG</sequence>
            </interactor>
            <interactor id="1385307">
                <names>
                    <shortLabel>ryr1_rabit</shortLabel>
                    <fullName>Ryanodine receptor 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">RYR1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle calcium release channel</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle-type ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Type 1 ryanodine receptor</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P11716" version="SP_120" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I0Y" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAX" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013333" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9R" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I1E" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014821" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I8M" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UWE" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071277" secondary="cellular response to calcium ion" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4P9J" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB0" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" secondary="protein homotetramerization" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I2S" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAV" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UWA" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FG3" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GL1" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9N" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAM" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219" secondary="ryanodine-sensitive calcium-release channel activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097718" secondary="disordered domain specific binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GKY" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_185"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-41872N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071313" secondary="cellular response to caffeine" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HSM" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ETU" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035761" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB3" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015278" secondary="calcium-release channel activity" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I3N" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAT" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J8V" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005245" secondary="voltage-gated calcium channel activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C30" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008144" secondary="drug binding" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" secondary="calmodulin binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" secondary="calcium channel activity" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016093" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035910" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001870" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014808" secondary="release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAP" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB1" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAY" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WOT" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009460" version="SP_185"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6477441" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ILA" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003032" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I6I" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9S" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GL0" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAN" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000699" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043931" secondary="ossification involved in bone maturation" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I37" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003877" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BCX" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I96" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAW" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7CF9" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048741" secondary="skeletal muscle fiber development" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TA3" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAL" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013662" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GKZ" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014802" secondary="terminal cisterna" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ERT" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" secondary="outflow tract morphogenesis" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAU" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ETT" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9M" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I7I" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9V" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FOO" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ESU" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031301" secondary="integral component of organelle membrane" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035762" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T15" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAS" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB4" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M2W" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070588" secondary="calcium ion transmembrane transport" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAZ" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035381" secondary="ATP-gated ion channel activity" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036300" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015643" secondary="toxic substance binding" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035764" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043136" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XOA" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3J8H" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RQR" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAQ" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB2" version="SP_185"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001095188.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9986">
                    <names>
                        <shortLabel>rabit</shortLabel>
                        <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rabbit</alias>
                    </names>
                </organism>
                <sequence>MGDGGEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLDTAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPRGSGPPAGPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRWDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGGWGEAEGGKEGTAKEGTPGGTPQPGVEAQPVRAENEKDATTEKNKKRGFLFKAKKAAMMTQPPATPALPRLPHDVVPADNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRKGGNARRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEEEEEEEEEEEEEDEEEKEEDEEEEEKEDAEKEEEEAPEGEKEDLEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDEADEEDCPLPEDIRQDLQDFHQDLLAHCGIQLEGEEEEPEEETSLSSRLRSLLETVRLVKKKEEKPEEELPAEEKKPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGETKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEERTEKKKTRKISQTAQTYDPREGYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLDRLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMAKAGDAQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIMLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEAEEEEVEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPEGEPEADEDEGMGEAAAEGAEEGAAGAEGAAGTVAAGATARLAAAAARALRGLSYRSLRRRVRRLRRLTAREAATALAALLWAVVARAGAAGAGAAAGALRLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGAGEGEGEGDAAEGDGDEEVAGHEAGPGGAEGVVAVADGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVDGEEEELVPEPEPEPEPEPEKADEENGEKEEVPEAPPEPPKKAPPSPPAKKEEAGGAGMEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDLAGAGSGGGSGWGSGAGEEAEGDEDENMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNERKPDPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS</sequence>
            </interactor>
            <interactor id="1385308">
                <names>
                    <shortLabel>f7e4c0_xentr</shortLabel>
                    <alias typeAc="MI:0302" type="gene name synonym">dtwd1</alias>
                    <alias typeAc="MI:0301" type="gene name">ryr1</alias>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676479" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSXETT00000031675"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001870"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013662"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036300"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035762"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035910"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005623"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005790"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035761"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014821"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048763"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009460"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-XTR-2672351"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003877"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSXETP00000006174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042383"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-XTR-5578775"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000699"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016093"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035764"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013333"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003032"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSXETG00000008787"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030659"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="8364">
                    <names>
                        <shortLabel>xentr</shortLabel>
                        <fullName>Xenopus tropicalis (Western clawed frog)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Silurana tropicalis</alias>
                    </names>
                </organism>
                <sequence>QFMQEDVVVLQCSATIRKEQIKMCMGAEGFGNRLCFLESTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEMGNESSQGGGHRTLLYGHAILLRHCHSDMYLCCLTTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPITSGCELAEGYVTGGHVLRLFHGHMDECLTIASTDQGEEQRRIPHYEGGAVCSHARSLWRLEPLRISWSGSHMKWGQSFRVRHVTTGRYLARDDEKGLVVLDAERANTKATAFCFRASKEKLDVAPKRDVEGMGIAEIKYGESMCFVQHVSSGLWLTYGALDAKVVRLGPLKRKAILHQEGHMDDALCLSRSQREESQASRMIYSTSGLFNLFIKGLDSLSGKNKPSKPVTLPIDMVILTLQDLIGYFQHPEDELQHEEKQTKLRSLKNRQNLFQEEGIISLVLDCIDRLNVYSTAAHFSEFAGEEAAESWKEIVNLLYELLAALIRGNRSNCALFSSNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIKENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQNLITENLLPRRDLLLQTRLVNYVTSMRPNVFLGTCEGSTQYKKWYYEMVVDHVEPFVTAEATHLRVGWAMTEGYSPYPGAGEGWGANGVGDDLYSFGFDGLHLWSGRVCRPVTSHNQHLLAADDVVSCCLDLTVPSISFRFNGHPVQGMFENFNLDGLFFPVVSFSAGINIRFLLGGRHGDFKFLPPPGYAPVYEALLPRDRMRIEPIKEYKHDFENIRNLLGPTKSLSHTSFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGTVVRDDNKRLHPCLLDFHNLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEENLKKIKLPKTYVMSNGYKPAPLDLSHVKLTPAQNTLVDKLAENGHNVWARDRVLQGWTYSIIQDIKNKRNPRLVPYSLLDEKTKKTNRDSLCEAVRTLIGYGYNIEPPDQESTAQGIIKARAERMRIFRAEKSYAVKSGKWYFEFEAVTTGEMRVGWVRPEVRPDVELGADELAYVFNGCRGQRWHIGSEPFGRNWLPGDVVGCMIDLTEMNIMFTLNGEMLISDSGSELAFKDIEIGDGFIPVCSLGMSQVGRLNLGQDVSSLRYFTICGLQEGFEPFAINMKRDITTWFSKSLPQFVNVPTDHAHIEVGRIDGTVDNPPCLKVTHKTFGSQNSNNDMQFFRLSMPVEFHETFKCTPGATPLTRTLTIPEDDVQEVDMDSEFEMLKKAVSRKEAEATNEKETAKEPPKEQIKPENEKDTASEKVKTKRGFLFKARKPAFISPPPVVPTMPRLMKDVVPDDRDDPEIIMNTTTYYYSVRIFAGQEPTGVWIGWVTPDYHLYDMNFDLSKVRVATITMGDDKGNIFNSIKRSNCYMVWGGEFGNNTQQARVRKEDLVIGCLIDLATGLMTFTANGKEVNTFFQVEPNTKLFPAVFASPQSQNMFQFELGKLKNIMPISAAMFRSENKNPVPQCPPRLEVQMLTPVVWSRMPNDFLNVESERISERQGWMVECSEPLMMMALHIPEESRCIDVLELSERLNMLKFHYHTLKLYCSVCALGNNRVAHALCSHVDESQLLYTIESNHLSGLLRSGYYDLLISIHLESEKRARLTMNNEFIVPMTEETKSITLFPNDNKKHGLPGVGMSTCLKPDLHFSHTCFVSTSTELYQLSPFIPLDVLKIKAINMLTEAVLDGGQHTRDPVGGSVEFQFVPVLKLISTLLIMGVFEDDDVRHILKMIEPNVFNEPESGLLQMKLPESVKLQMCNLLQYFCDRELQHRVEAIIAFSERHMESLQTNQRQRYKELMQAFTMTAAETARRTREFRSPPQEQINMLLNFRNLSEDDCPIPEDIRDELSEFHTDLLSHCGVQMEGEEEEEHEDTSLHKRLLNLVEKLKHFRKKEEPEPEPEEKEEPKPSTLQELISHTMVHWAQESFIQSPELVRVMFSLLHRQYDGLGELIRALPKAYTINAVSVEDTMNLLESLGQIRSLLIVQMGPEEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGDSKEIRFPKMVTNCCRFLCYFCRISRQNQRAMFDHLSYLLQNSGIGLGMRGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLSKGYPDIGWNPVGGERYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAIEEAIKISEDPARDGPTVKKDRRRELYGGEEVHEENRVHLGNAIMSFYSALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLPLQIPAFGKDGNPIEPKMSASFVPDHKAPMVLFLDRVYGIENQDFLLQVLEVGFLPDMRAAASLDTAAFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTIYRLSRGRSLTKAQRDVIEECLMALCRYLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPTGWANYGVTSEEELHLTRKLFWGIFESLAHKRFDAELYKIAMPCLCAIAGAIPPDYVDASYSSKTEKKASVDAEGNFDPKPIETLNVIIPEKLDGFINKYAEYTHDKWAFEKIQNNWSYGEAVDEEAKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGEDDKIEKKTKSRKISQSAQQTYDPTVQTFSPTPMDLTGITLSRELQSMAEQLAENYHNTWGRKKKQELESKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQINGYAVTRGLKDMELDTSSIEKRFAYGFLQKLLKLMDTAQEFIAHLEAVVSSGRVEKSPHEREIKFFAKILLPLINQYFKNHCLYFLSTPAKVLGSGGHASNKEKEMIASLFCKMAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFEGASEDIEKMVENLKLGKVSQSRTQVKGVAQNINYTTVALLPVLTSLFEHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKSPYVEKQRPALGECLARLAAAMPVAFLEPSLNEYNIYSVYTTKSPRERAILGLPNSVEEMCPDIPDLETLMKDISMLAESGARYTEMPHVIEVTLPMLCNYLPRWWERGPENIPDDSSPCCTSVTSEHLNTLLGNILRIVVNNLGIDEASWMKRLAVFAQPIVSKAKPELLRSHFIPTMEKLKKRAGKVVAEEEQLRMEAKSESEDSESLIRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNLDAEELFRMVGEVFIFWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMSKSGDSQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCSPTDQELITLAKTRYSLKDTDEEVREFLQNNLHLQGKCDNSSMRWQMALYNKMSGKAEDSNNPEKIVKRVQEVSAVLFHLELTEHPFKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPRHRACNMFLEGYKQAWIMSEAHDFEDRMIDDLSNFKYLHYIDSNESKEPDPLHQLILHFSRTALTEKSKLDEDYLYMAYADIMAKSCHMEDESEEAAEDEEEVELTFEEKEMEKQKLLYQQSRLHNRGAAEMVLQMISACKGEPGSMVSSTLKLGISILNGGNSDVQQKMLDYLKEKREVGFFQSVQALMQTCSVLDLNAFERQNKAEGLGMVTEDGTIINREQGEKVMADDQFTQDLFRLLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDIIDDQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIGLLKELLDLQKDMVVMLLSLLEGNIVNGTIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKAMDSQKQYTTSEIQFLLSCSEADENEMINFEEFADRFQEPAKDIGFNLAVLLTNLSEHVPNDTRLQNFLELADCIINYFKPYLGKIEIMGAGKRIERIYFEISEANKTQWEMPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQIASQISEPEEEKAEDDEDDVVEGSGEGEEAENGSSPQEASSAFGEFLNNVMNFFKMFTYKNLRRQYRKVKKMSFKEIILAIVSFLWTVFLGILHFVYSVCKGIFLLIWHTLFGGSLVEGAQKLTVTELLASMPDPTQDEVHSDGPAVAVSDEEPEAGDVTDFVDISKEEVQEEGTDIFGIDLKKEGGHYRASAPDAPGGLGDMGDTTPVEPPTPEGSPILKRKLADEETSGEEHDVVPEEEPAPEPEPEKADLENGEKTAEVQEETAPEPEEPEQPEVAPKKKSPARDKKPEAEEGGFEFWNELEIQRIKFLNYLSRNFYNLRFLALFLAFAINFILLFYKVSDSPLGEDDFEGSGIEDEISGMDDGGGDEDEEEEGPVYFVLEESTGYMQPTLYMLSVIHTLIAFLCIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQPEDDDIKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLASLEISSQNGKKQEPDKSLLSWFTSIDIKYQIWNFGVVFTDNSFLYLVWYMVMSLLGHYNNFFYAAHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFENHTLEEHNLANYMFFLMYLINKDDTEHTGQESYVWKMYQERCWDFFPAGDCFRKTYEDQLG</sequence>
                <attributeList>
                    <attribute name="no-uniprot-update">no candidate replacement found</attribute>
                </attributeList>
            </interactor>
            <interactor id="1385309">
                <names>
                    <shortLabel>ryr1_oncmy_protein</shortLabel>
                    <fullName>Ryanodine receptor 1</fullName>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6692507" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="8022">
                    <names>
                        <shortLabel>oncmy</shortLabel>
                        <fullName>Oncorhynchus mykiss (Rainbow trout)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Salmo gairdneri</alias>
                    </names>
                </organism>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">Similar to O13054</attribute>
                </attributeList>
            </interactor>
            <interactor id="1385310">
                <names>
                    <shortLabel>fkb1b_human</shortLabel>
                    <fullName>Peptidyl-prolyl cis-trans isomerase FKBP1B</fullName>
                    <alias typeAc="MI:0301" type="gene name">FKBP1B</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP12.6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP1L</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP9</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">OTK4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">12.6 kDa FK506-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FK506-binding protein 1B</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Immunophilin FKBP12.6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rotamase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">h-FKBP-12</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P68106" version="SP_95" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033197" secondary="response to vitamin E" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JMH" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0086064" secondary="cell communication by electrical coupling involved in cardiac conduction" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JIY" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAT" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB3" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051284" secondary="positive regulation of sequestering of calcium ion" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JRR" version="SP_167"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004107.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006458" secondary="'de novo' protein folding" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M2W" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HKG" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019855" secondary="calcium channel inhibitor activity" version="SP_167"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000119782" version="SP_167" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9S" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030551" secondary="cyclic nucleotide binding" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAP" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB1" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010459" secondary="negative regulation of heart rate" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAY" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WOT" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JMJ" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IQC" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9R" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061179" secondary="negative regulation of insulin secretion involved in cellular response to glucose stimulus" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PV6" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAX" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030073" secondary="insulin secretion" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6X34" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB0" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JI8" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WOV" version="SP_167"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16645" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003755" secondary="peptidyl-prolyl cis-trans isomerase activity" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4C02" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JHN" version="SP_167"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13664" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051280" secondary="negative regulation of release of sequestered calcium ion into cytosol" version="SP_167"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000370373" version="SP_167" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019227" secondary="neuronal action potential propagation" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6X36" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAV" version="SP_167"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53TM2" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022417" secondary="protein maturation by protein folding" version="SP_167"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5578775" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9N" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAM" version="SP_167"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000380986" version="SP_167" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JMF" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1C9H" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9M" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JRS" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAS" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB4" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051480" secondary="regulation of cytosolic calcium ion concentration" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JMG" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9V" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JI0" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010880" secondary="regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000413" secondary="protein peptidyl-prolyl isomerization" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042098" secondary="T cell proliferation" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T15" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAQ" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB2" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAZ" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JH6" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032515" secondary="negative regulation of phosphoprotein phosphatase activity" version="SP_167"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_473374.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JMI" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009749" secondary="response to glucose" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061077" secondary="chaperone-mediated protein folding" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051775" secondary="response to redox state" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6X32" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048680" secondary="positive regulation of axon regeneration" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035584" secondary="calcium-mediated signaling using intracellular calcium source" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IQ2" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010881" secondary="regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAN" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6X33" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005528" secondary="FK506 binding" version="SP_167"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48796N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WOU" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042026" secondary="protein refolding" version="SP_167"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2672351" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704" secondary="calcium channel complex" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6W1N" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042542" secondary="response to hydrogen peroxide" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006939" secondary="smooth muscle contraction" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JIU" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6X35" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JII" version="SP_167"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BQ40" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001179" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAW" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAL" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7CF9" version="SP_167"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6693977" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5L1D" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060315" secondary="negative regulation of ryanodine-sensitive calcium-release channel activity" version="SP_167"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAU" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JGZ" version="SP_167"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TA3" version="SP_167"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE</sequence>
            </interactor>
            <interactor id="1385311">
                <names>
                    <shortLabel>ryanodine</shortLabel>
                    <fullName>Ryanodine</fullName>
                </names>
                <xref>
                    <primaryRef db="chebi" dbAc="MI:0474" id="CHEBI:8925" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6857858" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>small molecule</shortLabel>
                        <fullName>small molecule</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0328" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619656" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="-2">
                    <names>
                        <shortLabel>chemical synthesis</shortLabel>
                        <fullName>Chemical synthesis (Chemical synthesis)</fullName>
                    </names>
                </organism>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-26050-1" id="1385312">
                <names>
                    <shortLabel>ryr1_fkbp12_1-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6656585" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385313">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6661929" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385305</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385314">
                                <names>
                                    <shortLabel>fkbp12_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6661931" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385315">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6661895" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385306</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9031">
                                <names>
                                    <shortLabel>chick</shortLabel>
                                    <fullName>Gallus gallus (Chicken)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Chicken</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-5" id="1385316">
                <names>
                    <shortLabel>ryr1_fkbp12_1-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662027" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-5" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385317">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662035" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385307</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9986">
                                <names>
                                    <shortLabel>rabit</shortLabel>
                                    <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rabbit</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385318">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662032" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385305</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385319">
                                <names>
                                    <shortLabel>fkbp12_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662042" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-9" id="1385320">
                <names>
                    <shortLabel>ryr1_fkbp12_1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676451" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-9" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385321">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676456" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385305</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385322">
                                <names>
                                    <shortLabel>fkbp12_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676464" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385323">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676454" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385308</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8355">
                                <names>
                                    <shortLabel>xenla</shortLabel>
                                    <fullName>Xenopus laevis (African clawed frog)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-11" id="1385324">
                <names>
                    <shortLabel>fkbp12-ryr1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838589" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-11" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385325">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838594" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385305</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385326">
                                <names>
                                    <shortLabel>fkbp12_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838597" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 5.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385327">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838592" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385309</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8022">
                                <names>
                                    <shortLabel>oncmy</shortLabel>
                                    <fullName>Oncorhynchus mykiss (Rainbow trout)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Salmo gairdneri</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 5.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-15" id="1385328">
                <names>
                    <shortLabel>ryr1_fkbp12.6_1-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6661996" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-15" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385329">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662007" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385306</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9031">
                                <names>
                                    <shortLabel>chick</shortLabel>
                                    <fullName>Gallus gallus (Chicken)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Chicken</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385330">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12.6</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662002" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385310</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385331">
                                <names>
                                    <shortLabel>fkbp12.6_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662004" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12.6</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-3" id="1385332">
                <names>
                    <shortLabel>ryr1_fkbp12.6_1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662024" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385333">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12.6</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662037" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385310</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385334">
                                <names>
                                    <shortLabel>fkbp12.6_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662040" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 3.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385335">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6662030" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385307</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9986">
                                <names>
                                    <shortLabel>rabit</shortLabel>
                                    <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Rabbit</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 3.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12.6</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-7" id="1385336">
                <names>
                    <shortLabel>ryr1_fkbp12.6_1-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676448" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-7" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385337">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676462" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385308</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8355">
                                <names>
                                    <shortLabel>xenla</shortLabel>
                                    <fullName>Xenopus laevis (African clawed frog)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">African clawed frog</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385338">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12.6</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676459" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385310</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385339">
                                <names>
                                    <shortLabel>fkbp12.6_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6676466" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12.6</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-13" id="1385340">
                <names>
                    <shortLabel>fkbp12_6-ryr1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838609" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-13" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385341">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FKBP12.6</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838614" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" refType="process" refTypeAc="MI:0359"/>
                        </xref>
                        <interactorRef>1385310</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1385342">
                                <names>
                                    <shortLabel>fkbp12.6_tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838617" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>radiolabelled</shortLabel>
                                        <fullName>radiolabel</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">radiolabeled</alias>
                                        <alias typeAc="MI:1041" type="synonym">radiolabelled</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0517" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608949" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>western blot</shortLabel>
                                        <fullName>western blot</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456832" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="1385343">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR1</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6838612" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385309</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="8022">
                                <names>
                                    <shortLabel>oncmy</shortLabel>
                                    <fullName>Oncorhynchus mykiss (Rainbow trout)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Salmo gairdneri</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Table 2, 3 and 4. Figure 4</attribute>
                    <attribute name="comment" nameAc="MI:0612">Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle

RYR1 contains 4 binding sites for FKBP12.6</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-16" id="1385344">
                <names>
                    <shortLabel>ryr-ryanodine-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857854" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-16" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385345">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857873" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385307</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1385346">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ryanodine</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857863" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385311</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1385347">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857865" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385306</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2 and table 2,3 and 4</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-18" id="1385348">
                <names>
                    <shortLabel>ryanodine-ryr-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857867" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-18" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385349">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ryanodine</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857869" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385311</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1385350">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857871" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385309</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2 and table 2,3 and 4</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-20" id="1385351">
                <names>
                    <shortLabel>ryanodine- ryr-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857875" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-20" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385352">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857881" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385307</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1385353">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ryanodine</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857879" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385311</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1385354">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857877" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385307</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2 and table 2,3 and 4</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26050-22" id="1385355">
                <names>
                    <shortLabel>ryanodine-ryr1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857883" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26050-22" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1385304</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1385356">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Ryanodine</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857887" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385311</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1385357">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RyR</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6857885" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1385308</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2 and table 2,3 and 4</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
