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    <entry>
        <source releaseDate="2013-03-27Z">
            <names>
                <shortLabel>UniProt</shortLabel>
                <fullName>UniProt</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0486" refType="identity" refTypeAc="MI:0356"/>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1371711">
                <names>
                    <shortLabel>lima-1997-1</shortLabel>
                    <fullName>MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="9261067" refType="primary-reference" refTypeAc="MI:0358"/>
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                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6551659" refType="identity" refTypeAc="MI:0356"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Lima C.D., D'Amico K.L., Naday I., Rosenbaum G., Westbrook E.M., Hendrickson W.A.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">hendw@convex.hhmi.columbia.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Structure (0969-2126)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1997</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1371712">
                <names>
                    <shortLabel>fhit_human</shortLabel>
                    <fullName>Bis(5'-adenosyl)-triphosphatase</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Diadenosine 5',5'''-P1,P3-triphosphate hydrolase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Dinucleosidetriphosphatase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">AP3A hydrolase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fragile histidine triad protein</alias>
                    <alias typeAc="MI:0301" type="gene name">FHIT</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Adenosine 5'-monophosphoramidase FHIT</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Adenylylsulfatase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Adenylylsulfate-ammonia adenylyltransferase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P49789" version="SP_77" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000189283" version="SP_190" refType="gene"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K1A9" version="SP_138" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000418582" version="SP_190" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006163" secondary="purine nucleotide metabolic process" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015964" secondary="diadenosine triphosphate catabolic process" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002003.1"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_190"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29947N"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FIT" version="SP_190"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYFQ</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-18697-1" id="1371713">
                <names>
                    <shortLabel>fhit-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="pdbe" dbAc="MI:0472" id="2fit" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pdbe" dbAc="MI:0472" id="3fit" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="pdbe" dbAc="MI:0472" id="1fit" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-18697-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1371711</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1371714">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6551669" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1371712</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 2.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="3d-resolution" nameAc="MI:0632">1.85 A for 1FIT
1.90 A for 2FIT
2.40 A for 3FIT</attribute>
                    <attribute name="3d-r-factors" nameAc="MI:0631">R-factor: 0.202 R-free: 0.225 for 1FIT; R-factor: 0.222 R-free: 0.249 for 2FIT; R-factor: 0.201 R-free: 0.249 for 3FIT</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">Table 1</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
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