UniProt UniProt http://www.uniprot.org pasdeloup-2013-3 Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. chlae-vero Chlorocebus (Cercopithecus) aethiops kidney cells Grivet vero Chlorocebus (Cercopithecus) aethiops kidney cells similar to cos-7 cells but these are not trasnformed anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Pasdeloup D., McElwee M., Beilstein F., Labetoulle M., Rixon F.J. Dystonin binding site coordinates are indicated in the publication according to a mouse isoform a (fig. 1a) which corresponds to UniProt IsoId=Q91ZU6-2 for mouse dystonin isoform 1/BPAG1-a. These coordinates have been adapted for the rat sequence. pasdeloup@vms.cnrs-gif.fr cDNA from PC2 cells (rat neuronal cell line) J. Virol. (0022-538X) 2013 Only protein-protein interactions imex curation pasdeloup-2013-1 Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Pasdeloup D., McElwee M., Beilstein F., Labetoulle M., Rixon F.J. Dystonin binding site coordinates are indicated in the publication according to a mouse isoform a (fig. 1a) which corresponds to UniProt IsoId=Q91ZU6-2 for mouse dystonin isoform 1/BPAG1-a. These coordinates have been adapted for the rat sequence. pasdeloup@vms.cnrs-gif.fr cDNA from PC2 cells (rat neuronal cell line) J. Virol. (0022-538X) 2013 Only protein-protein interactions imex curation pasdeloup-2013-2 Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Pasdeloup D., McElwee M., Beilstein F., Labetoulle M., Rixon F.J. Dystonin binding site coordinates are indicated in the publication according to a mouse isoform a (fig. 1a) which corresponds to UniProt IsoId=Q91ZU6-2 for mouse dystonin isoform 1/BPAG1-a. These coordinates have been adapted for the rat sequence. pasdeloup@vms.cnrs-gif.fr J. Virol. (0022-538X) 2013 Only protein-protein interactions imex curation f1m118_rat Dst protein protein rat Rattus norvegicus (Rat) Rat DERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVEVKWIEYQNMVNYLIQWIRHHVVTMSERTFPNNPLELKALYNQYLQFKEKEIPPKETEKSKIKRLYKLLEIWIEFGRIKLLQGYHPNDIEKEWGKLIIAMLEREKALRPEVERLDMLQQIATRVQRDSVSCEDKLMLARNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHVIDVQILLDGKYYQAEQLVQRVAKLRDEILALRNECSAVYSKGRMLTTEQTKLMISGITQSLNSGFAQTLHPSLNSGLTQSLTPSLTSSSVTSGLSSGMTSRLTPSVTPAYTPGFPSVVAPNFSVGVEPNSLQTLKLMQIRKPLLKSSLLDQNLTEEEVNMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTAPLKLSYTDKLHRLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNSNVARKKGYHAELMRELEQKEESIKAVQEIAEQLLLESHPARLTIEAYKAAMQTQWSWILQLCQCVEQHIQENTAYFEFFNDAKEATDYLRNLKDAIQRKYVCDRSSSIRKLEDLVQESMEKEELLQYRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQIEITIYKDDECVLANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHESHVNMKSIVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQESQIFSGSDITQLEKEVNVCRKYYQELLKSAEREEQEESVYNLYVSEVRNIRLRLESCEDRLIRQIRTPLERDDLHESMLRITEQEKLKKELERLKDDLEAITNKCEEFFSQAADSPSVPALRSELSVVLQSMSQIYSMSATYVEKLKTVNLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLMSTLKQWRSEVDEKREVFHALEDELQKAKAISDEMFKTHKERDLDFDWHKEKADQLVERWQSVHVQIDNRLRDLEGIGKSLKHYRDSYHPLDDWIQQIETTQRKIQENQPENSKALAVQLNQQKMLVSEIEVKQSKMDECQKYSEQYSAAVKDYELQTMTYRAMVDSQQKSPMKRRRIQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEKSLDEEKKQHVEKAKELQKWVSNISETLGDGERAGKPHFSKQQISSKEISAKKEQFSEALQNTQIFLAKHGDKLTEEDRSDLEKQVKTLQEGYNLLFSESLKQQELQPSGEAKVKVEEKPDKVIAGTINQTTGEVLSVFQAVLRGLIDYETGIRLLEAQLVISGLISPELRKCFDLKDAERHGLVDEQILGQLKELNEAKQIISTASPTMIPVLDSLDRGVISESVAIRVLEILLSTDSLVVPATGEHLTLQKAFQQNLISSALFSKVLERQAACKDLIDPCTSEKVSLTDMVQRSILQENTRMWLLPVRPQEAGRITLKCGRSVSILRAAHEGIIDRETMFRLLGAQLLSGGLVDCNSGQKMTVEEALAEGVIDRDTASSILTYQVRTGGILHSNPAKRLTVDEAVQCELITSSSALLVLEAQRGYVGLIWPHSGEIFPTASSLEQELITNELACKILNGRQKIAALYFPETSQVIDLDAARRLGIIDNNTASVLKHVTLPDKMPDLGDLEACKNARKWLSFCKFQPSTAHHYTQEEDGSDGDEPVAAQSSEQTKKLFLSYLMVNSYMDANTGRRLLLHDGDLEEAVGMLLESCGAELGAGTAVRESLSVLPVPDASPDCASSREKHGSGSDKCHYRHPGHKGPLENAKWDLNGELCEMGNNEDSGELPRLENLTDTTVAQKAGGPSSVRVPKPTSYSTQPELKNQSELDTEASPDEGIHSGVCTSETSRLCDASETEDEDHIQKGPSVFDYSPRLSALLSHDLLRHSQGSFSDTPKNTGYLCEASTLSSGDQSVLADQSTGEKLQDQFLGIAAISVSLQGAPCGQTPVDNGCSNCQVHYSSDEYMSDASAESGTTRQTSETEKTGSEVEDDSCTMIPGDGSCNANPSACRPLSLKGAIDAGDYETSLLAGQQSDTATDSDSDDYFYDTPLFEDEDHDSLILQGDDHDCLQPEDYDTLQEENDKTPPPDDIFYDVLKENENPESSPGGMDESLSAGGKVHFPQGFLVGTKRPELYVVDQKQFNLGDSDKMRERLAEPVPESETPSDLEHSESDSLTDGEITGRKESLGTSVTPGGRWRGDREECDTSQESQSDTDGVGFVQSIESSRLYMSDGSDRDEEDNGTYSSEDDDDRGGGGQEVAGENGEPSDPASHNQLYTATVKESGAETQSVRDTILLDRMHGYSPLEKQQRGRVLQPESAGKRGRDTERSNHPELTTEADEEDRASVSTHMATTGVSLSNAQGTASENVELVQGPGSTDILKDEDEYLENGSPKNGQPSNKIVCSEAGLGGGPSEESHLSFTVSNRGQRGTGRGQVKGRDGKNSQGVGEMSIQETGFREDGGLMSSPEEGEEERCLNPFPNGIATGSPNTGESLFTPLLTHTEELRHRGDPNTATMTLDCEAKDGQTGLRESPVLLETLAEIFDTSASKETHADPTSALRSSGVKSQVKEDSLTGGSEKETGPFTSPERCDKCVNVDVLESNKHTPSCAFIASPPMKDDLPTVTNAEEKPVIPQGDWPSGAKIQPSGACVKGSMSEGKAGIPHFTPEHSDTTLSLLPQKSVAECGGNTDFVQAQLHMNGVRNTSDNTLDVGCPRLESSREKERTEKQPHGERTSSPRPQERVHTPEFGEDGGTLKSGLDKVQMNLQDVGDPSACTGTTISIQNLIKRAILSELPNETSNVPSPGVSPINNSSEEKAENRGDPLCIASLLEILKQDQHTQETPGTSELIKVLTQTACNPEERGLVSGLFPPQLKNVFCKLLLDGYSAEREQAEALKQTPGAAPEMVEEKPCDCSDLKSKEGNHYTPNPQTVREAGVEHSGVHTAALPRDEEFGELCSEPPDHSECTSGSKEISSDDNTKEKCSNGLQQCLQHTEKMHEYLALLQDMKPPLDNQAAMENSLEALKNQLKQLETFELGLAPMAVFLRKDLKLAEEFLKSFPSDLPGRHHEELSKSHERLQNAFESLSSVSSQRMKLITLAIDTETSKLAVRHEDFLHRLTSYSDWVSEKSRSVADIQTVNVQDTELVKNSVKFLKARNVLTDLSHTKVQLETTAFDIQSFISDYAQDLSPNQSRQLLRLLNTTQKCFLDVQELVTSEVVRLETLLQLEQELGHQKVVAERQQEYKEKLQGLCDLLTQTENRLISHQETFVIGDGTVELKKYQSKQEELQRDMQGSTQALAEIVRNTEIFLKESGDELSQEDKALIEQKLNEAKVKCEQLNLKAEQSTKELDKVVTAALKEETEKVAAARQLEESKTKIENLLNWLSNVEKDSEGSGRLHTQPLEQNGTHLHEGDGTSEAGEEDEVNGNLLETDAEGHGGMTEGNLNQQYEKVKAQHEKIVAQHQAVIMATQSAQALLEKQGHHLSPEEKEKLQANVQELKAHYETVLAECEKKVKLTHSLQEELEKFDADCGEFEHWLQQSEQELENLEAGADDLSGLTDKLARQKSFSEDVISHKGDLRYITISGNRVMEAAKSCSKRDGDRIGKDSLETSATHREVQTKLDQVTDRFRCLYSKCSVLGNNLKDLVDKYQHYEDASCGLLSGLQACEAKASRHLLEPIALDPKNLQRQLEETKALQGQISSQQAAVEKLKKTAEVLLDAKGSLLPAKNDIQKTLDDIVGRYDDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGSVESSLVKQGQVPLNSTALQDLISKNIMLDQDITGRQSSINAMNEKVKTFIETTDPSTASSLQAKMKDLSARFSEASQKHKEKLAKMVELKSKVEEFEKLSDKLQTFLETQSQALTEVDMPGKDVPELSQHMQESTTKFLEHRKDLEALHSLLKEISSHGLPGDKALVFEKTNNLSKKFKELEDTIQEKKEALSSCQEQLSAFHDLAQSLKTWIKETTKQVPIVKPSFGTEDLEKSLEETKKLQEKWSLKTPEIHKANNSGVSLCNLLSALISPAKAIAAARSGGVILNGEGTDTNTQDFLANKGLTSIKTDMTDISHSYEDLGLLLKDKIVELNTKLSKLQKAQEESSAMMQWLQKMNKTASRWRQTPTPADSESVKIQVEQNKSFEAELKQNVNKVQELKDKLAELLKENPEAPEAPSWKQTMAEMDTKWQELNQLTIDRQQKLEESSNNLSQFQTTEAQLKQWLVEKELMVSVLGPLSTDPNMLNTQKQQAQILLQEFDTRKPQYEQLTAAGQGILSRPGEDPSLHGIVKEQLAAVTQKWDNLTGQLRDRCDWIDQAIVKSTQYQSLLRSLSGTLTELDEKLSSSLISGTLPDAVNQQLEAAQKLKQEIEQQTPKIKEAQTLCEDLSALVKEEYLRAELSRQLEGVLKSFKDIEQKTENHVQHLQSACASSHQFQQMSKDFQAWLDAKKEEQRNSPPISAKLDVLESLLKAQKDFGKTFTEQSNIYEKTVAEGENLLSKTQGAEKAALQLQLNTIKTDWDRFRKQVKEREEKLKESLEKALRYREQVDTLQPWVDKCQHSLESVKLSLDPADTERSITELKTLQKEMDHHFGTLELLNNSANSLLSVCEVDKEVVTEGNKSLIQKVNVVTEQLQSKKVSLENMAQKFKEFQEVSKDAKRQLQDTKEQLEVYQSLGPQACSNKHLTMLQAQQKSLQTLKHQVDSARRLAQDLVMEATDPKGTSDVLSQAETLAEEHRGLSQQVDEKCSFLETKLQGLGHFQNTIREMFSQFTEFDDELDSMAPVGRDVETLQKQKASMQTFLKKLEALITSNDSANRTCKMMLATEETSPDLIGVKRDLEALSKQCNKLLDRAKTREEQVSGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPVGTETDAINQQLDVFKIFQKEEIEPLQAKQQDVNWLGQGLIQSAAANTCTQGLEHDLDSINARWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEAIKREGEKIAASAEPADRVKLSRQLSLLDSRWEMLLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGTQAPKLEEQIAQHKALQEDILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEHALQLAGQLQSKHKELCNWLDRVEVELLSYETQGLKGEAASQVQERQKELKNEVRNNKALLDSLNEVSSALLELVPWRAREGLEKTVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETQKKLMSLGCIRLEQDQTSAQLQAQKAFTMDILRHKDIIDELVTSGHKIMTTSSEEEKQSMKKKLDKVLKKYDAICQINSERHLQLERAQSLVSQFWETYEELWPWLMETQQIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPKEGVHIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERIAERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIARSEGTEKDISAKAVQDKLDQMVFIWGSIHTLVEDREAKLLDVMELAEKFWCDHMSLVVTTKDTQDFIRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWKDRIDRLGEAMQAAVQYQDGLQAIFDWVDIAGNKLATMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEVDKHTVQDPLMELKLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSEGEEASNLQYKLRILNQRWQDILEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAREQLNAHMEVCTAFAIKEETYKNLMLRGQQMLARCPRSVETNIDQDITNLKEKWESVKSKLNEKKTKLEEALHLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEARKRAKQFHEAWSKLMEWLEDSEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSVYDTTNRTGRSLKEKTSLADDTLKLENMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKRSARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTLLEWLAEAEQTLRFHGALPDDEDALRTLIEQHKEFMKKLEEKRAELNKATGMGDALLTACHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLENLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPPSLQSHIPVLDKGRAGRKRFPASGLYPSGSQTQIETKNPRANLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRVSKEKQFFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSASSHACQAASPQVPAAASTPKILHPLTRNYGKPWLANSKMSTPCKAAECPDFPVSSAEGTPIQGSKLRLPGYLSGKGFHSGEDNALITTAASRVRTQFAESRKTPSRPGSRAGSKAGSRASSRRGSDASDFDISEIQSVCSDVETVPQTHRPAPRAGSRPSTAKPSKIPTPQRKSPASKLDKSSKR The sequence has been withdrawn from uniprot. itp_hhv11 Inner tegument protein UL37 Viral deamidase UL37 protein protein hhv11 Human herpesvirus 1 (strain 17) (HHV-1) Human herpes simplex virus 1 HHV-1 MADRGLPSEAPVVTTSPAGPPSDGPMQRLLASLAGLRQPPTPTAETANGADDPAFLATAKLRAAMAAFLLSGTAIAPADARDCWRPLLEHLCALHRAHGLPETALLAENLPGLLVHRLVVALPEAPDQAFREMEVIKDTILAVTGSDTSHALDSAGLRTAAALGPVRVRQCAVEWIDRWQTVTKSCLAMSPRTSIEALGETSLKMAPVPLGQPSANLTTPAYSLLFPAPFVQEGLRFLALVSNRVTLFSAHLQRIDDATLTPLTRALFTLALVDEYLTTPERGAVVPPPLLAQFQHTVREIDPAIMIPPLEANKMVRSREEVRVSTALSRVSPRSACAPPGTLMARVRTDVAVFDPDVPFLSSSALAVFQPAVSSLLQLGEQPSAGAQQRLLALLQQTWTLIQNTNSPSVVINTLIDAGFTPSHCTHYLSALEGFLAAGVPARTPTGHGLGEVQQLFGCIALAGSNVFGLAREYGYYANYVKTFRRVQGASEHTHGRLCEAVGLSGGVLSQTLARIMGPAVPTEHLASLRRALVGEFETAERRFSSGQPSLLRETALIWIDVYGQTHWDITPTTPATPLSALLPVGQPSHAPSVHLAAATQIRFPALEGIHPNVLADPGFVPYVLALVVGDALRATCSAAYLPRPVEFALRVLAWARDFGLGYLPTVEGHRTKLGALITLLEPAARGGLGPTMQMADNIEQLLRELYVISRGAVEQLRPLVQLQPPPPPEVGTSLLLISMYALAARGVLQDLAERADPLIRQLEDAIVLLRLHMRTLSAFFECRFESDGRRLYAVVGDTPDRLGPWPPEAMGDAVSQYCSMYHDAKRALVASLASLRSVITETTAHLGVCDELAAQVSHEDNVLAVVRREIHGFLSVVSGIHARASKLLSGDQVPGFCFMGQFLARWRRLSACYQAARAAAGPEPVAEFVQELHDTWKGLQTERAVVVAPLVSSADQRAAAIREVMAHAPEDAPPQSPAADRVVLTSRRDLGAWGDYSLGPLGQTTAVPDSVDLSRQGLAVTLSMDWLLMNELLRVTDGVFRASAFRPLAGPESPRDLEVRDAGNSLPAPMPMDAQKPEAYGHGPRQADREGAPHSNTPVEDDEMIPEDTVAPPTDLPLTSYQ ul37-dst-4 1424993 n/a 1424996 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection n-terminal myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false the binding site corresponds to mouse aa 526-851 common to most isoforms (displayed in fig 1B is mouse isoform a/1 corresponding to UniProt Ac Q91ZU6-2); the rat seq used here is a fragment n/a 1424997 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection n-terminal ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false physical association physical association false false false 1C dst-ul37 1424993 n/a 1424997 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection n-terminal ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false n/a 1424996 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false the binding site corresponds to mouse aa 526-851 common to most isoforms (displayed in fig 1B is mouse isoform a/1 corresponding to UniProt Ac Q91ZU6-2); the rat seq used here is a fragment physical association physical association false false false 1D ul37-dst-3 1424994 n/a 1424996 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false the binding site corresponds to mouse aa 526-851 common to most isoforms (displayed in fig 1B is mouse isoform a/1 corresponding to UniProt Ac Q91ZU6-2); the rat seq used here is a fragment n/a 1424997 unspecified role unspecified role bait bait physical association physical association false false false no figure ul37-dst-2 1424995 n/a 1424997 unspecified role unspecified role bait bait region required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false n/a 1424996 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false the binding site corresponds to mouse aa 526-851 common to most isoforms (displayed in fig 1B is mouse isoform a/1 corresponding to UniProt Ac Q91ZU6-2); the rat seq used here is a fragment physical association physical association false false false 1B A construct spanning aminoacids 517-899 did not bind to f1m118, although the shorter 578-899 fragment did.