UniProt UniProt http://www.uniprot.org ch_vez-2012-2 Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation. mouse-testis Mus musculus testis testis anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Chávez J.C., Hernández-González E.O., Wertheimer E., Visconti P.E., Darszon A., Treviño C.L. ctrevino@ibt.unam.mx Biol. Reprod. (0006-3363) 2012 Only protein-protein interactions imex curation ch_vez-2012-1 Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation. mouse-testis Mus musculus testis testis confocal microscopy confocal microscopy immunostaining immunostaining Chávez J.C., Hernández-González E.O., Wertheimer E., Visconti P.E., Darszon A., Treviño C.L. ctrevino@ibt.unam.mx Biol. Reprod. (0006-3363) 2012 Only protein-protein interactions imex curation s26a6_mouse Solute carrier family 26 member 6 Slc26a6 Anion exchange transporter Cfex Chloride-formate exchanger Pat1 Pendrin-L1 Pendrin-like protein 1 Putative anion transporter-1 protein protein mouse Mus musculus Mouse MGLPDGSDQGTHQTQALLSAAQEMELQRRDYHVERPLLNQEQLEDLGHWGPAAKTHQWRTWFRCSRARAHSLLLQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLTADKAFVQGLNATADDARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLSSHSGPLSVIYTVLEVCAQLPETVPGTVVTAIVAGVALVLVKLLNEKLHRRLPLPIPGELLTLIGATGISYGVKLNDRFKVDVVGNITTGLIPPVAPKTELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVVRMQLPHYSVLGQVPDTDIYRDVAEYSGAKEVPGVKVFRSSATLYFANAELYSDSLKEKCGVDVDRLITQKKKRIKKQEMKLKRMKKAKKSQKQDASSKISSVSVNVNTNLEDVKSNDVEGSEAKVHQGEELQDVVSSNQEDAKAPTMTSLKSLGLPQPGFHSLILDLSTLSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPVVAQLEAGHFFDESITKQHVFASVHDAVTFALSHRKSVPKSPVLATKL s26a3_mouse Chloride anion exchanger Slc26a3 Dra Down-regulated in adenoma Solute carrier family 26 member 3 protein protein mouse Mus musculus Mouse MIEAIGNQYVVARPVYSTKTFGEEFKKTHRHHKTFLDHLKGCCSCSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVVSDPNASSELSSSSTENDSFIEEKVMVAASVTVLSGIIQLLLGVLQVGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLPVPAYSDPFSIFKVLESVFTQIQKTNIADLVTSVIILVVVFVFKEINQRYRSKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLGFQPPITPSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYAEVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHILMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF nhrf1_mouse Na(+)/H(+) exchange regulatory cofactor NHE-RF1 Slc9a3r1 Nherf Nherf1 Ezrin-radixin-moesin-binding phosphoprotein 50 Regulatory cofactor of Na(+)/H(+) exchanger Sodium-hydrogen exchanger regulatory factor 1 Solute carrier family 9 isoform A3 regulatory factor 1 protein protein mouse Mus musculus Mouse MSADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREELLRPQEKSEQAEPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFFKKCKVIPSQEHLDGPLPEPFSNGEIQKESSREALVEPASESPRPALARSASSDTSEELNSQDSPKRQVSTEPSSTSSSSSDPILDLNISLAVAKERAHQKRSSKRAPQMDWSKKNELFSNL cftr_mouse Cystic fibrosis transmembrane conductance regulator Cftr Abcc7 ATP-binding cassette sub-family C member 7 Channel conductance-controlling ATPase cAMP-dependent chloride channel protein protein mouse Mus musculus Mouse MQKSPLEKASFISKLFFSWTTPILRKGYRHHLELSDIYQAPSADSADHLSEKLEREWDREQASKKNPQLIHALRRCFFWRFLFYGILLYLGEVTKAVQPVLLGRIIASYDPENKVERSIAIYLGIGLCLLFIVRTLLLHPAIFGLHRIGMQMRTAMFSLIYKKTLKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFIWIAPLQVTLLMGLLWDLLQFSAFCGLGLLIILVIFQAILGKMMVKYRDQRAAKINERLVITSEIIDNIYSVKAYCWESAMEKMIENLREVELKMTRKAAYMRFFTSSAFFFSGFFVVFLSVLPYTVINGIVLRKIFTTISFCIVLRMSVTRQFPTAVQIWYDSFGMIRKIQDFLQKQEYKVLEYNLMTTGIIMENVTAFWEEGFGELLEKVQQSNGDRKHSSDENNVSFSHLCLVGNPVLKNINLNIEKGEMLAITGSTGSGKTSLLMLILGELEASEGIIKHSGRVSFCSQFSWIMPGTIKENIIFGVSYDEYRYKSVVKACQLQQDITKFAEQDNTVLGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEEQVFESCVCKLMANKTRILVTSKMEHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSKLMGYDTFDQFTEERRSSILTETLRRFSVDDSSAPWSKPKQSFRQTGEVGEKRKNSILNSFSSVRKISIVQKTPLCIDGESDDLQEKRLSLVPDSEQGEAALPRSNMIATGPTFPGRRRQSVLDLMTFTPNSGSSNLQRTRTSIRKISLVPQISLNEVDVYSRRLSQDSTLNITEEINEEDLKECFLDDVIKIPPVTTWNTYLRYFTLHKGLLLVLIWCVLVFLVEVAASLFVLWLLKNNPVNSGNNGTKISNSSYVVIITSTSFYYIFYIYVGVADTLLALSLFRGLPLVHTLITASKILHRKMLHSILHAPMSTISKLKAGGILNRFSKDIAILDDFLPLTIFDFIQLVFIVIGAIIVVSALQPYIFLATVPGLVVFILLRAYFLHTAQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFRRQTYFETLFHKALNLHTANWFMYLATLRWFQMRIDMIFVLFFIVVTFISILTTGEGEGTAGIILTLAMNIMSTLQWAVNSSIDTDSLMRSVSRVFKFIDIQTEESMYTQIIKELPREGSSDVLVIKNEHVKKSDIWPSGGEMVVKDLTVKYMDDGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRMLNIKGDIEIDGVSWNSVTLQEWRKAFGVITQKVFIFSGTFRQNLDPNGKWKDEEIWKVADEVGLKSVIEQFPGQLNFTLVDGGYVLSHGHKQLMCLARSVLSKAKIILLDEPSAHLDPITYQVIRRVLKQAFAGCTVILCEHRIEAMLDCQRFLVIEESNVWQYDSLQALLSEKSIFQQAISSSEKMRFFQGRHSSKHKPRTQITALKEETEEEVQETRL slc26a3-slc26a6 1426802 n/a 1426804 unspecified role unspecified role bait bait n/a 1426805 unspecified role unspecified role prey prey physical association physical association false false false 3A slc26a6-slc9a3r1 1426802 n/a 1426805 unspecified role unspecified role prey prey n/a 1426806 unspecified role unspecified role bait bait physical association physical association false false false 3A cftr-slc9a3r1-3 1426802 n/a 1426805 unspecified role unspecified role prey prey n/a 1426807 unspecified role unspecified role bait bait physical association physical association false false false 3A slc26a3-slc26a6-1 1426802 n/a 1426805 unspecified role unspecified role bait bait n/a 1426804 unspecified role unspecified role prey prey physical association physical association false false false 3B slc26a3-slc9a3r1 1426802 n/a 1426804 unspecified role unspecified role prey prey n/a 1426806 unspecified role unspecified role bait bait physical association physical association false false false 3B cftr-slc9a3r1-4 1426802 n/a 1426804 unspecified role unspecified role prey prey n/a 1426807 unspecified role unspecified role bait bait physical association physical association false false false 3B cftr-slc26a6-1 1426802 n/a 1426807 unspecified role unspecified role bait bait n/a 1426806 unspecified role unspecified role prey prey physical association physical association false false false 3C cftr-slc26a6-2 1426802 n/a 1426804 unspecified role unspecified role bait bait n/a 1426806 unspecified role unspecified role prey prey physical association physical association false false false 3C slc26a3-slc26a6-2 1426802 n/a 1426806 unspecified role unspecified role prey prey n/a 1426805 unspecified role unspecified role bait bait physical association physical association false false false 3C slc26a3-cftr 1426802 n/a 1426805 unspecified role unspecified role bait bait n/a 1426807 unspecified role unspecified role prey prey physical association physical association false false false 3D slc26a3-slc26a6-3 1426802 n/a 1426804 unspecified role unspecified role bait bait n/a 1426807 unspecified role unspecified role prey prey physical association physical association false false false 3D slc26a6-slc9a3r1-1 1426802 n/a 1426807 unspecified role unspecified role prey prey n/a 1426806 unspecified role unspecified role bait bait physical association physical association false false false 3D cftr-slc9a3r1-2 1426803 n/a 1426807 unspecified role unspecified role neutral component neutral component n/a 1426806 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2C cftr-slc26a6 1426803 n/a 1426807 unspecified role unspecified role neutral component neutral component n/a 1426804 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2B cftr-slc26a3 1426803 n/a 1426805 unspecified role unspecified role neutral component neutral component n/a 1426807 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2A