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    <entry>
        <source releaseDate="2012-06-15+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
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                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
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                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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        </source>
        <experimentList>
            <experimentDescription id="1286216">
                <names>
                    <shortLabel>wang-2010h-2</shortLabel>
                    <fullName>The role of ezrin-associated protein network in human sperm capacitation.</fullName>
                </names>
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                        <primaryRef db="pubmed" dbAc="MI:0446" id="20711218" refType="primary-reference" refTypeAc="MI:0358"/>
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                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-sperm</shortLabel>
                            <fullName>Homo sapiens - sperm</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>sperm</shortLabel>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:1011" refType="identity" refTypeAc="MI:0356"/>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang L., Chen W., Zhao C., Huo R., Guo X.J., Lin M., Huang X.Y., Mao Y.D., Zhou Z.M., Sha J.H.</attribute>
                    <attribute name="comment" nameAc="MI:0612">The interaction between Ezrin and Actin has not been annotated as the type of Actin is not specified.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">drmaoyd@yahoo.com.cn, zhouzm@njm.edu.cn</attribute>
                    <attribute name="journal" nameAc="MI:0885">Asian J. Androl. (1008-682X)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
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                </attributeList>
            </experimentDescription>
            <experimentDescription id="1286217">
                <names>
                    <shortLabel>wang-2010h-1</shortLabel>
                    <fullName>The role of ezrin-associated protein network in human sperm capacitation.</fullName>
                </names>
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                    <xref>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-sperm</shortLabel>
                            <fullName>Homo sapiens - sperm</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>sperm</shortLabel>
                            </names>
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                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>fluorescence imaging</shortLabel>
                        <fullName>fluorescence microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">fluorescence imaging</alias>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>immunostaining</shortLabel>
                        <fullName>immunostaining</fullName>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang L., Chen W., Zhao C., Huo R., Guo X.J., Lin M., Huang X.Y., Mao Y.D., Zhou Z.M., Sha J.H.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">drmaoyd@yahoo.com.cn, zhouzm@njm.edu.cn</attribute>
                    <attribute name="journal" nameAc="MI:0885">Asian J. Androl. (1008-682X)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1286218">
                <names>
                    <shortLabel>ezri_human</shortLabel>
                    <fullName>Ezrin</fullName>
                    <alias typeAc="MI:0301" type="gene name">EZR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">VIL2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p81</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cytovillin</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Villin-2</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051117" secondary="ATPase binding" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072659" secondary="protein localization to plasma membrane" version="SP_233"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010737" secondary="protein kinase A signaling" version="SP_233"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000338934" version="SP_233" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045296" secondary="cadherin binding" version="SP_233"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL</sequence>
            </interactor>
            <interactor id="1286219">
                <names>
                    <shortLabel>gdir1_human</shortLabel>
                    <fullName>Rho GDP-dissociation inhibitor 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Rho-GDI alpha</alias>
                    <alias typeAc="MI:0301" type="gene name">ARHGDIA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">GDIA1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P52565" version="SP_72" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FST" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N80" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BXW" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071407" secondary="cellular response to organic cyclic compound" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288172.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHZ" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013404" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000580685" version="SP_202" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000269321" version="SP_202" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHO" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024792" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001172007.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288169.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DUV9" version="SP_134" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000406" version="SP_202"/>
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                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8MXW0" version="SP_134" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-718039" refType="intact-secondary"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1QVY" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JI0" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHX" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035023" secondary="regulation of Rho protein signal transduction" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" secondary="cellular response to mechanical stimulus" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000141522" version="SP_202" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005856" secondary="cytoskeleton" version="SP_202"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHY" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000441348" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071526" secondary="semaphorin-plexin signaling pathway" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288170.1"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P52565" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-193634" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014756" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHV" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005096" secondary="GTPase activator activity" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013408" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FSO" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FT0" version="SP_202"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6IBM5" version="SP_103" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030336" secondary="negative regulation of cell migration" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001772" secondary="immunological synapse" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000541078" version="SP_202" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005504" secondary="fatty acid binding" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHW" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000269321" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8980692" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005094" secondary="Rho GDP-dissociation inhibitor activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008360" secondary="regulation of cell shape" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CC0" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071461" secondary="cellular response to redox state" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000464205" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288171.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007266" secondary="Rho protein signal transduction" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FT3" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHT" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHS" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013148" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004300.1"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-712693" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007162" secondary="negative regulation of cell adhesion" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032880" secondary="regulation of protein localization" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JHU" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001172006.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013149" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013407" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1HH4" version="SP_202"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2R5X1" version="SP_103" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051879" secondary="Hsp90 protein binding" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013106" version="SP_202"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2840752" refType="intact-secondary"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1KMT" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-209563" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031267" secondary="small GTPase binding" version="SP_202"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEEAPKGMLARGSYSIKSRFTDDDKTDHLSWEWNLTIKKDWKD</sequence>
            </interactor>
            <interactor id="1286220">
                <names>
                    <shortLabel>rhoa_human</shortLabel>
                    <fullName>Transforming protein RhoA</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Rho cDNA clone 12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ARHA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RHO12</alias>
                    <alias typeAc="MI:0301" type="gene name">RHOA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ARH12</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P61586" version="SP_51" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007519" secondary="skeletal muscle tissue development" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6KX3" version="SP_202"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000503282" version="SP_202" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019003" secondary="GDP binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060193" secondary="positive regulation of lipase activity" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IRC" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050773" secondary="regulation of dendrite development" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009612" secondary="response to mechanical stimulus" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043296" secondary="apical junction complex" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3KZ1" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030307" secondary="positive regulation of cell growth" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4D0N" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021795" secondary="cerebral cortex cell migration" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T06" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904695" secondary="positive regulation of vascular associated smooth muscle contraction" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032154" secondary="cleavage furrow" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045471" secondary="response to ethanol" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005856" secondary="cytoskeleton" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001822" secondary="kidney development" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051924" secondary="regulation of calcium ion transport" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043931" secondary="ossification involved in bone maturation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003924" secondary="GTPase activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905274" secondary="regulation of modification of postsynaptic actin cytoskeleton" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051384" secondary="response to glucocorticoid" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HPY" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045666" secondary="positive regulation of neuron differentiation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043149" secondary="stress fiber assembly" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BCA" version="SP_202"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005225" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5666185" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097498" secondary="endothelial tube lumen extension" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JHH" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043525" secondary="positive regulation of neuron apoptotic process" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007015" secondary="actin filament organization" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V6U" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903427" secondary="negative regulation of reactive oxygen species biosynthetic process" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4XSH" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030496" secondary="midbody" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042476" secondary="odontogenesis" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051893" secondary="regulation of focal adhesion assembly" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5625900" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RGN" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_202"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001655.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5U024" version="SP_51" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" secondary="positive regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003925" secondary="G protein activity" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045727" secondary="positive regulation of translation" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0101003" secondary="ficolin-1-rich granule membrane" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904706" secondary="negative regulation of vascular associated smooth muscle cell proliferation" version="SP_202"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LWN" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6KX2" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031098" secondary="stress-activated protein kinase signaling cascade" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031234" secondary="extrinsic component of cytoplasmic side of plasma membrane" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060071" secondary="Wnt signaling pathway, planar cell polarity pathway" version="SP_202"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_202"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53HM4" version="SP_84" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5A0F" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002363" secondary="alpha-beta T cell lineage commitment" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5625970" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071803" secondary="positive regulation of podosome assembly" version="SP_202"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29642N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904753" secondary="negative regulation of vascular associated smooth muscle cell migration" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005525" secondary="GTP binding" version="SP_202"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785631" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098978" secondary="glutamatergic synapse" version="SP_202"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990869" secondary="cellular response to chemokine" version="SP_202"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CXZ" version="SP_202"/>
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                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
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                    <alias typeAc="MI:0302" type="gene name synonym">CDw44</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Phagocytic glycoprotein I</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Extracellular matrix receptor III</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HUTCH-I</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Phagocytic glycoprotein 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">GP90 lymphocyte homing/adhesion receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Hermes antigen</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Hyaluronate receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Heparan sulfate proteoglycan</alias>
                    <alias typeAc="MI:0301" type="gene name">CD44</alias>
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                    <alias typeAc="MI:0302" type="gene name synonym">MDU2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MDU3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MIC4</alias>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031258" secondary="lamellipodium membrane" version="SP_245"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000428726" version="SP_245" refType="transcript"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B6EAT9" version="SP_159" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC30" version="SP_127" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UCB0" version="SP_130" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_245"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000538" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034116" secondary="positive regulation of heterotypic cell-cell adhesion" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC29" version="SP_127" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16208" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005540" secondary="hyaluronic acid binding" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033138" secondary="positive regulation of peptidyl-serine phosphorylation" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UJ36" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016186" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007155" secondary="cell adhesion" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005518" secondary="collagen binding" version="SP_245"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PZ4" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q04858" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13968" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044319" secondary="wound healing, spreading of cells" version="SP_245"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2I83" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86T72" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_245"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-490245" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044344" secondary="cellular response to fibroblast growth factor stimulus" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13961" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050731" secondary="positive regulation of peptidyl-tyrosine phosphorylation" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13419" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1POZ" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13958" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16064" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000398632" version="SP_245" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13980" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005925" secondary="focal adhesion" version="SP_245"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UUH" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8N694" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A5YRN9" version="SP_124" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070487" secondary="monocyte aggregation" version="SP_245"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-1121N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035692" secondary="macrophage migration inhibitory factor receptor complex" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_245"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H5A5" version="SP_122" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_245"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001001392.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042995" secondary="cell projection" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86Z27" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000601.3"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_245"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2160916" version="SP_245"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001231" version="SP_245"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O95370" version="SP_160" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030214" secondary="hyaluronan catabolic process" version="SP_245"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-20562-2" id="1286222">
                <names>
                    <shortLabel>ezr-arhgdia</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6095995" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20562-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1286216</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1286223">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096000" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286218</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1286224">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6095999" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-20562-3" id="1286225">
                <names>
                    <shortLabel>rhoa-arhgdia</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096001" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20562-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1286216</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1286226">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096003" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1286227">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096004" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286220</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-20562-4" id="1286228">
                <names>
                    <shortLabel>ezr-arhgdia-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096006" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20562-4" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1286216</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1286229">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096009" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286221</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1286230">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6096008" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286218</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 3E</attribute>
                    <attribute name="comment" nameAc="MI:0612">Ezrin interacts with the glycosylated and native forms of cd44 after capacitation.</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-20562-1" id="1286231">
                <names>
                    <shortLabel>arhgdia-ezr</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6095981" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001669" secondary="acrosomal vesicle" refType="component" refTypeAc="MI:0354"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036126" secondary="sperm flagellum" refType="component" refTypeAc="MI:0354"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20562-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1286217</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1286232">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6095984" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286219</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1286233">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6095983" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1286218</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 1C</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
