IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ ruprecht-2009-1 Structure of Escherichia coli succinate:quinone oxidoreductase with an occupied and empty quinone-binding site. ecoli Escherichia coli (strain K12) x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ruprecht J., Yankovskaya V., Maklashina E., Iwata S., Cecchini G. s.iwata@imperial.ac.uk, gary.cecchini@ucsf.edu J. Biol. Chem. (0021-9258) 2009 Only protein-protein interactions imex curation sdha_ecoli Succinate dehydrogenase flavoprotein subunit sdhA b0723 JW0713 protein protein ecoli Escherichia coli (strain K12) MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY dhsc_ecoli Succinate dehydrogenase cytochrome b556 subunit sdhC cybA b0721 JW0711 protein protein ecoli Escherichia coli (strain K12) MIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW sdhb_ecoli Succinate dehydrogenase iron-sulfur subunit sdhB b0724 JW0714 protein protein ecoli Escherichia coli (strain K12) MRLEFSIYRYNPDVDDAPRMQDYTLEADEGRDMMLLDALIQLKEKDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRDLVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCPSFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPKGLNPTRAIGHIKSMLLQRNA dhsd_ecoli Succinate dehydrogenase hydrophobic membrane anchor subunit sdhD b0722 JW0712 protein protein ecoli Escherichia coli (strain K12) MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV carboxin 2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) pcp pentachlorophenol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) dhsabcd complex empty q-site 1330712 n/a 1330713 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330714 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330715 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330716 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 physical association physical association false false false Fig. 1, 4 3.2 A Rworking = 0.21 Rfree = 0.23 carboxin-sdha 1330712 n/a 1330714 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330713 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330716 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330715 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330717 unspecified role unspecified role neutral component neutral component physical association physical association false false false Fig. 1, 4 2.4 A Rworking = 0.17 Rfree = 0.2 pcp-sdha 1330712 n/a 1330718 unspecified role unspecified role neutral component neutral component n/a 1330714 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330713 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330716 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 n/a 1330715 unspecified role unspecified role neutral component neutral component Stoichiometry: 3.0 physical association physical association false false false Fig. 1, 4 3.2 A Rworking = 0.2 Rfree = 0.23